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MDRO & CDI
Multidrug-Resistant Organism & Clostridioides difficile (MDRO/CDI) Infection Surveillance and LabID Event Reporting Module
- Chapter 12: MDRO & CDI Module Protocol – January 2024 [PDF – 1 MB]
- 2024 Patient Safety Component Summary of Updates [PDF – 248 KB]
Supporting Chapters
- Chapter 1: NHSN Overview – January 2024 [PDF – 350 KB]
- Chapter 3: Patient Safety Monthly Reporting Plan – January 2024 [PDF – 300 KB]
- Chapter 15: CDC Location Labels and Location Descriptions – January 2024 [PDF – 1 MB]
- Chapter 16: NHSN Key Terms – January 2024 [PDF – 300 KB]
- Chapter 17: CDC/NHSN Surveillance Definitions for Specific Types of Infections – January 2024 [PDF – 1 MB]
All Data Collection Forms are Print-only
MDRO/CDI Events
- Laboratory-identified MDRO or CDI Event (57.128) [PDF – 100 KB]
- MDRO or CDI Infection Event (57.126) [PDF – 100 KB]
Denominator Form
Supporting Forms
- Analysis Resources
- Analysis Quick Reference Guides
- How to see “Create” and “Modify” dates within NHSN [PDF – 400 KB]
- Troubleshooting MRSA and CDI LabID Event SIR [PDF – 220 KB]
- NHSN’s Guide to the SIR (2022 Baseline) [PDF – 901 KB] – A comprehensive guide to NHSN’s SIR, including risk factors used in the SIR calculations under the 2022 baseline.
- NHSN’s Guide to the SIR (2015 Baseline) [PDF – 50 Pages]– A comprehensive guide to NHSN’s SIR, including risk factors used in the SIR calculations under the 2015 baseline.
- PSC – Data Dictionary [XLS – 1 MB]
The resources below can be used by all facility types and will assist in the analysis of MDRO/CDI Module data.
General Analysis Resources
- Analysis Resources
- Analysis Quick Reference Guides
- Variable Reference List [PDF – 3 MB]
- Data Dictionary [XLS – 862 KB]
- Keys to Success with NHSN Data
- How to see “Create” and “Modify” dates within NHSN [PDF – 400 KB]
SIRs on the 2015 Baseline
- Troubleshooting MRSA and CDI LabID Event SIR [PDF – 220 KB]
- NHSN’s Guide to the SIR – March 2019 [PDF – 2 MB]
SIRs on the 2010 – 2011 Original Baseline
- Risk Adjustment for Healthcare Facility-Onset C. difficile and MRSA Bacteremia Laboratory-identified Event Reporting in NHSN March 2013 [PDF – 406 KB]
This report describes the risk modeling that CDC applied to LabID event CDI and MRSA bacteremia data submitted to NHSN, the results of which have been incorporated into the analysis options in the NHSN application
MDRO & CDI Training
Educational Roadmap
CMS Requirements
MDRO & CDI LabID Event Calculator
MDRO & CDI LabId Event Calculator
(must have javascript enabled)
Operates based upon the currently posted LabID Event protocols in the NHSN MDRO & CDI Module.
Resources to Help Prevent HAIs
- CDC Vital Signs: Making Healthcare Safer
- SHEA-IDSA Guideline Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2018 Update by SHEA and IDSA
- CDC Infection Control Guidance Library
- Guideline for Hand Hygiene in Healthcare Settings [PDF – 500 KB]
- Diseases and Organisms in Healthcare Settings, Including Resources for Patients and Healthcare Providers
- HHS Action Plan to Prevent Healthcare-associated Infections
- Management of Multidrug-Resistant Organisms In Healthcare Settings, 2006 [PDF – 600 KB]
- Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings, 2007
- Guideline for Environmental Infection Control in Healthcare Facilities, 2003
- C. difficile Excerpt
