Outcomes of infants* born in 2021 to persons with hepatitis B and managed by the CDC Perinatal Hepatitis B Prevention Program through the end of 2022 — 64 US Jurisdictions
Hepatitis B vaccine administration | Post-vaccination serologic testing | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Jurisdiction | All infants managed* | HBIG & vaccine at birth | Complete series by 12 months of age | Complete series after 12 months of age | Total with complete series | Received† | HBsAg positive | Immune§ | |||||||
No. | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % ¶ | |
All jurisdictions | 7,102 | 6,718 | 95% | 6,267 | 88% | 97 | 1% | 6,364 | 90% | 4,631 | 65% | 17 | 0% | 4,412 | 95% |
State | |||||||||||||||
Alabama | 95 | 12 | 13% | 11 | 12% | 1 | 1% | 12 | 13% | 8 | 8% | 0 | 0% | 7 | 88% |
Alaska | 28 | 28 | 100% | 18 | 64% | 0 | 0% | 18 | 64% | 6 | 21% | 0 | 0% | 6 | 100% |
Arizona | 117 | 101 | 86% | 88 | 75% | 6 | 5% | 94 | 80% | 65 | 56% | 0 | 0% | 63 | 97% |
Arkansas | 43 | 43 | 100% | 41 | 95% | 2 | 5% | 43 | 100% | 30 | 70% | 0 | 0% | 24 | 80% |
California | 1,070 | 1,039 | 97% | 991 | 93% | 7 | 1% | 998 | 93% | 667 | 62% | 2 | 0% | 629 | 94% |
Colorado | 97 | 93 | 96% | 88 | 91% | 2 | 2% | 90 | 93% | 69 | 71% | 0 | 0% | 63 | 91% |
Connecticut | 54 | 47 | 87% | 53 | 98% | 0 | 0% | 53 | 98% | 16 | 30% | 0 | 0% | 8 | 50% |
Delaware | 38 | 37 | 97% | 16 | 42% | 7 | 18% | 23 | 61% | 22 | 58% | 0 | 0% | 21 | 95% |
Florida | 238 | 208 | 87% | 179 | 75% | 4 | 2% | 183 | 77% | 53 | 22% | 0 | 0% | 48 | 91% |
Georgia | 232 | 225 | 97% | 219 | 94% | 2 | 1% | 221 | 95% | 200 | 86% | 0 | 0% | 195 | 98% |
Hawaii | 88 | 88 | 100% | 85 | 97% | 0 | 0% | 85 | 97% | 80 | 91% | 0 | 0% | 79 | 99% |
Idaho | 12 | 10 | 83% | 7 | 58% | 1 | 8% | 8 | 67% | 7 | 58% | 0 | 0% | 6 | 86% |
Illinois | 127 | 124 | 98% | 126 | 99% | 0 | 0% | 126 | 99% | 86 | 68% | 0 | 0% | 84 | 98% |
Indiana | 92 | 92 | 100% | 88 | 96% | 0 | 0% | 88 | 96% | 84 | 91% | 0 | 0% | 84 | 100% |
Iowa | 88 | 87 | 99% | 84 | 95% | 0 | 0% | 84 | 95% | 69 | 78% | 0 | 0% | 67 | 97% |
Kansas | 49 | 48 | 98% | 48 | 98% | 0 | 0% | 48 | 98% | 31 | 63% | 0 | 0% | 26 | 84% |
Kentucky | 84 | 82 | 98% | 69 | 82% | 6 | 7% | 75 | 89% | 22 | 26% | 0 | 0% | 21 | 95% |
Louisiana | 63 | 41 | 65% | 44 | 70% | 3 | 5% | 47 | 75% | 43 | 68% | 0 | 0% | 40 | 93% |
Maine | 10 | 10 | 100% | 9 | 90% | 0 | 0% | 9 | 90% | 7 | 70% | 0 | 0% | 7 | 100% |
Maryland | 167 | 159 | 95% | 117 | 70% | 20 | 12% | 137 | 82% | 135 | 81% | 0 | 0% | 135 | 100% |
Massachusetts | 204 | 202 | 99% | 194 | 95% | 0 | 0% | 194 | 95% | 172 | 84% | 1 | 1% | 165 | 96% |
Michigan | 111 | 111 | 100% | 110 | 99% | 0 | 0% | 110 | 99% | 101 | 91% | 0 | 0% | 101 | 100% |
Minnesota | 327 | 326 | 100% | 314 | 96% | 4 | 1% | 318 | 97% | 243 | 74% | 2 | 1% | 231 | 95% |
Mississippi | 50 | 49 | 98% | 39 | 78% | 2 | 4% | 41 | 82% | 27 | 54% | 0 | 0% | 26 | 96% |
Missouri | 78 | 75 | 96% | 73 | 94% | 1 | 1% | 74 | 95% | 47 | 60% | 0 | 0% | 46 | 98% |
Montana | 3 | 3 | 100% | 3 | 100% | 0 | 0% | 3 | 100% | 3 | 100% | 0 | 0% | 3 | 100% |
Nebraska | 38 | 38 | 100% | 33 | 87% | 0 | 0% | 33 | 87% | 32 | 84% | 0 | 0% | 32 | 100% |
Nevada | 53 | 51 | 96% | 50 | 94% | 1 | 2% | 51 | 96% | 28 | 53% | 0 | 0% | 26 | 93% |
New Hampshire | 18 | 18 | 100% | 17 | 94% | 1 | 6% | 18 | 100% | 5 | 28% | 0 | 0% | 5 | 100% |
New Jersey | 186 | 158 | 85% | 93 | 50% | 1 | 1% | 94 | 51% | 63 | 34% | 0 | 0% | 43 | 68% |
New Mexico | 14 | 13 | 93% | 14 | 100% | 0 | 0% | 14 | 100% | 10 | 71% | 0 | 0% | 9 | 90% |
New York | 232 | 226 | 97% | 226 | 97% | 2 | 1% | 228 | 98% | 194 | 84% | 0 | 0% | 190 | 98% |
North Carolina | 135 | 131 | 97% | 124 | 92% | 5 | 4% | 129 | 96% | 104 | 77% | 1 | 1% | 100 | 96% |
North Dakota | 36 | 36 | 100% | 36 | 100% | 0 | 0% | 36 | 100% | 15 | 42% | 0 | 0% | 15 | 100% |
Ohio | 200 | 181 | 90% | 183 | 92% | 1 | 0% | 184 | 92% | 88 | 44% | 0 | 0% | 83 | 94% |
Oklahoma | 77 | 73 | 95% | 63 | 82% | 0 | 0% | 63 | 82% | 33 | 43% | 0 | 0% | 22 | 67% |
Oregon | 49 | 41 | 84% | 39 | 80% | 3 | 6% | 42 | 86% | 32 | 65% | 1 | 3% | 29 | 91% |
Pennsylvania | 163 | 159 | 98% | 163 | 100% | 0 | 0% | 163 | 100% | 142 | 87% | 0 | 0% | 138 | 97% |
Rhode Island | 23 | 23 | 100% | 23 | 100% | 0 | 0% | 23 | 100% | 23 | 100% | 0 | 0% | 23 | 100% |
South Carolina | 54 | 53 | 98% | 49 | 91% | 0 | 0% | 49 | 91% | 32 | 59% | 0 | 0% | 32 | 100% |
South Dakota | 16 | 16 | 100% | 12 | 75% | 0 | 0% | 12 | 75% | 7 | 44% | 0 | 0% | 7 | 100% |
Tennessee | 98 | 93 | 95% | 95 | 97% | 1 | 1% | 96 | 98% | 68 | 69% | 1 | 1% | 64 | 94% |
Texas | 550 | 512 | 93% | 425 | 77% | 1 | 0% | 426 | 77% | 276 | 50% | 0 | 0% | 264 | 96% |
Utah | 63 | 63 | 100% | 57 | 90% | 0 | 0% | 57 | 90% | 39 | 62% | 1 | 3% | 37 | 95% |
Vermont | 9 | 5 | 56% | 7 | 78% | 0 | 0% | 7 | 78% | 0 | 0% | 0 | 0 | ||
Virginia | 189 | 184 | 97% | 177 | 94% | 2 | 1% | 179 | 95% | 119 | 63% | 0 | 0% | 118 | 99% |
Washington | 215 | 210 | 98% | 195 | 91% | 4 | 2% | 199 | 93% | 132 | 61% | 0 | 0% | 126 | 95% |
West Virginia | 11 | 10 | 91% | 11 | 100% | 0 | 0% | 11 | 100% | 11 | 100% | 0 | 0% | 11 | 100% |
Wisconsin | 86 | 85 | 99% | 81 | 94% | 3 | 3% | 84 | 98% | 55 | 64% | 1 | 2% | 53 | 96% |
Wyoming | 1 | 1 | 100% | 1 | 100% | 0 | 0% | 1 | 100% | 1 | 100% | 0 | 0% | 1 | 100% |
Cities** | |||||||||||||||
Chicago | 55 | 55 | 100% | 52 | 95% | 0 | 0% | 52 | 95% | 36 | 65% | 1 | 3% | 34 | 94% |
District of Columbia | 18 | 17 | 94% | 18 | 100% | 0 | 0% | 18 | 100% | 15 | 83% | 0 | 0% | 13 | 87% |
Houston | 88 | 82 | 93% | 86 | 98% | 0 | 0% | 86 | 98% | 56 | 64% | 0 | 0% | 53 | 95% |
New York City | 663 | 660 | 100% | 644 | 97% | 1 | 0% | 645 | 97% | 606 | 91% | 2 | 0% | 591 | 98% |
Philadelphia | 101 | 97 | 96% | 98 | 97% | 0 | 0% | 98 | 97% | 87 | 86% | 0 | 0% | 85 | 98% |
San Antonio | 35 | 30 | 86% | 31 | 89% | 1 | 3% | 32 | 91% | 19 | 54% | 0 | 0% | 17 | 89% |
Territories | |||||||||||||||
American Samoa | 2 | 2 | 100% | 1 | 50% | 1 | 50% | 2 | 100% | 0 | 0% | 0 | 0% | 0 | 0% |
Guam | 7 | 7 | 100% | 2 | 29% | 1 | 14% | 3 | 43% | 0 | 0% | 0 | 0% | 0 | 0% |
N. Mariana Islands | 7 | 6 | 86% | 6 | 86% | 0 | 0% | 6 | 86% | 6 | 86% | 0 | 0% | 6 | 100% |
Puerto Rico | 1 | 1 | 100% | 1 | 100% | 0 | 0% | 1 | 100% | 0 | 0% | 0 | 0% | 0 | 0% |
Virgin Islands | 2 | 2 | 100% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% |
Freely associated states | |||||||||||||||
Republic of the Marshall Islands | 12 | 12 | 100% | 12 | 100% | 0 | 0% | 12 | 100% | 0 | 0% | 0 | 0% | 0 | 0% |
The Federated States of Micronesia | 19 | 16 | 84% | 17 | 89% | 0 | 0% | 17 | 89% | 0 | 0% | 0 | 0% | 0 | 0% |
Republic of Palau | 11 | 11 | 100% | 11 | 100% | 0 | 0% | 11 | 100% | 4 | 36% | 4 | 100% | 0 | 0% |
Source: National Perinatal Hepatitis B Prevention Program (PHBPP), Immunization Services Division, CDC.
* These data only include infants followed by the CDC Perinatal Hepatitis B Prevention Program. National and jurisdictional level HepB vaccination coverage rates are available via annual The Morbidity and Mortality Weekly Report (MMWR) publications of National Immunization Survey data and via VaxView.
† Post-vaccination serologic testing (PVST) includes a test for HBsAg, anti-HBs, or both. Results from PVST may be reported as HBsAg positive, HBsAg negative and immune or not immune, or indeterminate.
§ Anti-HBs ≥10 mIU/mL.
¶ Percentage is among infants that completed the vaccine series and received PVST.
** City data are mutually exclusive from state data.
HBIG: Hepatitis B immune globulin.
HepB: Hepatitis B vaccine.
HBsAg: Hepatitis B surface antigen.
anti-HBs: Antibody to hepatitis B surface antigen.
This table summarizes outcome data on infants born to persons with hepatitis B from the CDC Perinatal Hepatitis B Prevention Program (PHBPP). The 2021 birth cohort includes infants born in 2021 and followed through December 31, 2022.
Among the 7,102 infants whose care was managed by the PHBPP, 95% received recommended prophylaxis at birth, 90% completed the vaccine series (regardless of prophylaxis), and 65% received recommended post-vaccination serologic testing.
Among infants who received post-vaccination testing (n = 4,631), there were 17 (0.4%) cases of perinatal hepatitis B transmission.