Vaccine-Preventable Adult Diseases

In the United States

• CDC estimates that since 2010, flu-related hospitalizations in the United States have ranged from 140,000 to 710,000 and flu related deaths have ranged from 12,000 to 56,000.
• About 320,000 people get pneumococcal pneumonia every year, leading to over 150,000 hospitalizations and 5,000 deaths, mostly among the elderly.
• About 880,000 people have chronic hepatitis B, which can cause serious health problems, including liver damage, cirrhosis, liver cancer, and even death.
• HPV causes over 27,000 cancers in women and men each year. About 4,000 women die each year from cervical cancer.

Learn About Serious Diseases that Can Be Prevented by Vaccines

Chickenpox (Varicella)

What it is

Chickenpox is a disease caused by the varicella zoster virus.

How it can affect you

Chickenpox causes an itchy rash with blisters, tiredness, headache and fever. Chickenpox is usually mild, but it can lead to severe skin infections, pneumonia, encephalitis (brain swelling), or even death.

Vaccine for Protection

Varicella

See the Varicella (Chickenpox) Vaccination page for more information.

Diptheria

What it is

Diphtheria is a very contagious bacterial disease that affects the respiratory system, including the lungs.

How it can affect you

Diphtheria produces a toxin (poison) in the body that can cause weakness, sore throat, low-grade fever, and swollen glands in the neck. Effects from this toxin can also lead to swelling of the heart muscle and, in some cases, heart failure. In severe cases, the illness can cause coma, paralysis, and even death.

Vaccine for Protection

Tdap, Td

See the Diphtheria Vaccination page for more information.

Flu (Influenza)

What it is

Influenza is a contagious viral infection of the nose, throat, and lungs. Older adults and those with certain health conditions are at high risk for serious complications.

How it can affect you

Influenza virus can cause a sudden high fever, chills, a dry cough, headache, runny nose, sore throat, and muscle and joint pain. Extreme fatigue can last from several days to weeks. Influenza may lead to hospitalization or even death.

Vaccine for Protection

Annual Flu

See the Seasonal Influenza (Flu) Vaccination page for more information.

Hepatitis A

What it is

Hepatitis A is an infection in the liver caused by hepatitis A virus. This disease is often spread through contaminated food.

How it can affect you

Hepatitis A can cause fever, tiredness, loss of appetite, nausea, abdominal discomfort, dark urine, and jaundice (yellowing of the skin and eyes). An infected person may have no symptoms, may have mild illness for a week or two, or may have severe illness for several months that requires hospitalization.

Vaccine for Protection

HepatitisA

See the Hepatitis A Vaccination page for more information.

Hepatitis B

What it is

Hepatitis B is an infection of the liver caused by hepatitis B virus. This is a blood-borne disease and can be very serious.

How it can affect you

Hepatitis B causes a flu-like illness with loss of appetite, nausea, vomiting, rashes, joint pain, and jaundice. The virus stays in the liver of some people for the rest of their lives and can result in severe liver diseases, including fatal cancer.

Vaccine for Protection

Hepatitis B vaccine is available for all age groups. The hepatitis B vaccine is recommended for all infants, all children or adolescents younger than 19 years of age who have not been vaccinated, all adults age 19 through 59 years, and adults age 60 years or older with risk factors for hepatitis B infection. Adults who are 60 years or older without known risk factors for hepatitis B may also receive hepatitis B vaccine.

Adults who are at risk for hepatitis B infection include healthcare workers, adults who have certain chronic health conditions like diabetes, renal disease, chronic liver disease, or HIV infection, and adults who are at risk of sexually transmitted infections.

All recommended age groups should get a 2-dose or 3-dose vaccine series (depending on the manufacturer) for protection from hepatitis B virus infection. There is also a 3-dose combination vaccine series available for people age 18 years or older; the combination vaccine can also be administered before travel on a 4-dose accelerated schedule.

See the Hepatitis B Vaccination page for more information.

Human Papillomavirus (HPV)

What it is

Human papillomavirus is a common virus, especially among people in their teens and early 20s. Many people don't know they have this for years until cancer appears.

How it can affect you

HPV is the major cause of cervical cancer in women, as well as anal cancer and genital warts in both women and men. Some types of HPV can cause cancers of the penis, anus, or oropharynx (back of the throat, including base of the tongue and tonsils).

Vaccine for Protection

HPV

See the HPV Vaccination page for more information.

Measles

What it is

Measles is respiratory disease caused by a very contagious virus. More and more cases are coming into the US, usually from international travelers.

How it can affect you

Measles can cause persistent fever, rash lasting up to a week, and coughing that can last about 10 days. Measles can also cause pneumonia, seizures, brain damage, or death.

Vaccine for Protection

MMR

See the Measles Vaccination page for more information.

Meningococcal Disease

What it is

Meningococcal disease is caused by bacteria and is a leading cause of bacterial meningitis (infection around the brain and spinal cord).

How it can affect you

Meningococcal disease can cause nausea, vomiting, sensitivity to light, confusion and sleepiness. Meningococcal disease also causes blood infections. About one out of every ten people who get the disease dies from it. Survivors of meningococcal disease may lose their arms or legs, become deaf, have problems with their nervous systems, become developmentally disabled, or suffer seizures or strokes.

Vaccines for Protection

MenACWY, MenB

See the Meningococcal Vaccination page for more information.

Mumps

What it is

Mumps is an infectious disease caused by the mumps virus.

How it can affect you

The mumps virus causes fever, headaches, painful swelling of the salivary glands under the jaw, fever, muscle aches, tiredness, and loss of appetite. Severe complications can include meningitis (infection of the covering of the brain and spinal cord), encephalitis (inflammation of the brain), permanent hearing loss, or swelling of the testes, which can lead to sterility in men in rare cases.

Vaccine for Protection

MMR

See the Mumps Vaccination page for more information.

Pneumococcal Disease

What it is

Pneumococcal disease is caused by bacteria and can range from ear and sinus infections to more serious lung and blood infections.

How it can affect you

When pneumococcal bacteria spread from the nose and throat to ears or sinuses, it generally causes mild infections. When the bacteria spread into other parts of the body, it leads to severe health problems, such as infections of the lungs (pneumonia), blood (bacteremia), and the lining of the brain and spinal cord (meningitis). In some cases pneumococcal disease can be life-threatening or result in long-term problems, like brain damage, hearing loss, or loss of arms or legs.

Vaccine for Protection

PCV13, PPSV23

See the Pneumococcal Vaccination page for more information.

Respiratory Syncytial Virus

What it is

Respiratory syncytial (sin-SISH-uhl) virus, or RSV, is a common respiratory virus of the nose, throat, and lungs that usually causes mild, cold-like symptoms. While most people recover in a week or two, RSV can be serious, especially for infants and older adults.

How it can affect you

RSV can cause fever, coughing, wheezing, sneezing, runny nose, and a decrease in appetite in both children and adults. Adults who get infected with RSV usually have mild or no symptoms. However, RSV can be dangerous for some people. Older adults and adults with certain chronic medical conditions are at highest risk of more severe disease with symptoms like trouble breathing and low oxygen levels. Severe RSV disease can lead to hospitalization or death.

Vaccine for Protection

• RSVPreF3 (Arexvy)
• RSVpreF (Abrysvo)

See the RSV Vaccination page for more information.

Rubella

What it is

Rubella is a viral disease that causes fever and rash.

How it can affect you

Rubella usually causes a mild illness with fever, swollen glands, and a rash that lasts about 3 days. In some cases, it can lead to encephalitis (brain infection) in adults. If a pregnant woman is infected with rubella, it can result in miscarriage or serious birth defects such as mental retardation, heart defects, and loss of hearing and eye sight.

Vaccine for Protection

MMR

See the Rubella (German Measles) Vaccination page for more information.

Shingles (Zoster)

What it is

Shingles is a painful skin rash that is caused by the varicella zoster virus, the same virus that causes chickenpox.

How it can affect you

Shingles causes a painful rash on one side of the face or body, which blisters and then typically scabs over in 7-10 days and clears up within 2-4 weeks. Other symptoms of shingles can include fever, headache, chills, and upset stomach. Shingles can affect the eye and cause loss of vision.

Vaccine for Protection

Zoster

See the Shingles (Herpes Zoster) Vaccination page for more information.

Tetanus

What it is

Tetanus is a serious bacterial disease that causes painful tightening of muscles. You can get this from a cut or wound, even a needle prick.

How it can affect you

The bacteria causing Tetanus produce a toxin (poison) in the body that causes serious, painful spasms and stiffness of all muscles in the body. This can lead to "locking" of the jaw so a person cannot open his or her mouth, swallow, or breathe. Three out of ten people who get tetanus die from the disease.

Vaccine for Protection

Tdap, Td

See the Tetanus (Lockjaw) Vaccination page for more information.

Whooping Cough (Pertussis)

What it is

Whooping cough is a highly contagious respiratory tract infection caused by bacteria. Since the 1980s, there has been an increase in the number of reported cases of pertussis in the United States. Babies too young to get vaccinated are most at risk of severe illness.

How it can affect you

Whooping cough can cause prolonged cold symptoms, leading to spells of violent coughing and choking, making it hard to breathe, drink, or eat. This cough can last for weeks. Whooping cough is most severe for babies, leading to hospitalization and sometimes death. Babies often get the disease from a parent, caregiver, or relative.

Vaccine for Protection

Tdap

See the Pertussis (Whooping Cough) Vaccination page for more information.