Key points
This web page contains the latest national information about vaccine supplies and provides guidance to healthcare providers who are facing vaccine shortages or delays.
Background
*Note: Only those vaccines included on the recommended childhood, adolescent, and adult immunization schedules for routine vaccination are included in this update.
Chart of Vaccines* in Delay or Shortage
National Vaccine Supply Shortages
| Vaccine | Shortage | Temporary Change From Routine Recommendation |
|---|---|---|
| Diphtheria, Tetanus, & Pertussis (DTaP) | No1 | |
| Haemophilus influenzae type B (Hib) | No | |
| Hepatitis A | No | |
| Hepatitis B | No | |
| Human Papillomavirus (HPV) | No | |
| Inactivated Polio (IPV) | No | |
| Influenza | No | |
| Measles, Mumps, & Rubella (MMR) | No | |
| Meningococcal Conjugated (MCV4) | No | |
| Pneumococcal Conjugated (PCV) | No | |
| Pneumococcal Polysaccharide (PPV) | No | |
| Respiratory syncytial virus (RSV) | No | |
| Rotavirus | No | |
| Serogroup B Meningococcal (MenB) | No | |
| Td and Tdap | Yes2 | Get more information on Constrained U.S. Td supply, 2024 |
| Varicella | No | |
| Zoster | No |
1Sanofi Pasteur has decided to discontinue production and distribution of Diphtheria and Tetanus Toxoids Adsorbed® (DT) and is withdrawing its licenses in all countries. The last lot was manufactured in October 2020 with an expiry date of April 2023. Sanofi expects to exhaust available supply by the end of 2022.
2MassBiologics has discontinued production of their Td vaccine, TdVax.TM Grifols, who is the exclusive distributor for TdVaxTM expects to have product available through approximately June 2024. Sanofi, who manufacturers Tenivac,® is taking steps to augment their available supply of Td for the US. However, it is anticipated that the supply of Td vaccine in the US market will be constrained during 2024. Temporary ordering controls have been put into place in the public and private sectors to help manage the gap in supply. Tdap vaccine is available from both US-licensed manufacturers without supply constraints at this time.
Why are there vaccine shortages?
In the United States shortages of many vaccines in the recommended childhood immunization schedule occurred in the past. Some of these shortages were widespread while others were localized. Reasons for these shortages were multi-factorial and included companies leaving the vaccine market, manufacturing or production problems, and insufficient stockpiles. Consequently, some shortages were only specific to one manufacturer.
Shortages of several of these vaccines necessitated temporary changes in recommendations for their use. During that period, summary information about the shortages including projected duration and recommendations for temporary changes in the childhood immunization schedule were provided.
Who can I contact to answer my questions?
- Questions including those dealing with changes in child care and school requirements necessitated by vaccine supply problems when they occur can be answered by State Health Department immunization programs.
- General immunization questions can be answered by CDC-INFO at 1-800-CDC-INFO
(1-800-232-4636) English and Español.
Acronyms and Abbreviations
Those acronyms and abbrevations not already spelled out above include
- AAFP – American Academy of Family Physicians
- AAP – American Academy of Pediatrics
- ACIP – Advisory Committee on Immunization Practices
- CDC – Centers for Disease Control and Prevention
- FDA – Food and Drug Administration
- GAO – United States General Accounting Office
- GSK – GlaxoSmithKline
- MMRV – Measles, Mumps, Rubella, and Varicella combination vaccine
- MMWR – Morbidity and Mortality Weekly Report
- NCIRD – National Center for Immunization and Respiratory Diseases
- TTY – teletypewriter
- Other acronyms