Adult Immunization Schedule by Age

Recommendations for Ages 19 Years or Older, United States, 2025

Purpose

Guide health care providers in determining recommended vaccines for each age group.

How to use the schedule

To make vaccination recommendations, healthcare providers should:

  1. Determine recommended vaccine by age (Table 1 - By Age)
  2. Assess need for additional recommended vaccinations by medical condition or other indication (Table 2 - By Medical Condition)
  3. Review vaccine types, dosing frequencies and intervals, and considerations for special situations (Notes)
  4. Review contraindications and precautions for vaccine types (Appendix)
  5. Review new or updated ACIP guidance (Addendum)

Ages 19 Years or Older

Legend

Recommended vaccination for adults who meet age requirement, lack documentation of vaccination, or lack evidence of immunity Recommended vaccination for adults with an additional risk factor or another indication Recommended vaccination based on shared clinical decision-making No Guidance/Not Applicable
Vaccine 19-26 years 27-49 years 50-64 years ≥65 years
COVID-19 more info icon. 1 or more doses of 2024–2025 vaccine (See Notes) 2 or more doses of 2024-2025 vaccine
(See Notes)
Influenza inactivated (IIV3, ccIIV3)
Influenza recombinant (RIV3) more info icon.
1 dose annually 1 dose annually
(HD–IIV3, RIV3, or aIIV3 preferred)
Influenza inactivated
(aIIV3; HD–IIV3)
Influenza recombinant (RIV3) more info icon.
Solid organ transplant (See Notes)
Influenza live, attenuated (LAIV3) more info icon. 1 dose annually
Respiratory Syncytial Virus
(RSV) more info icon.
Seasonal administration during pregnancy.

(See Notes)

60 through 74 years
(See Notes)
≥75 years
Tetanus, diphtheria, pertussis
(Tdap or Td) more info icon.
1 dose Tdap each pregnancy; 1 dose Td/Tdap for wound management (See Notes)
1 dose Tdap, then Td or Tdap booster every 10 years
Measles, mumps, rubella
(MMR) more info icon.
1 or 2 doses depending on indication
(if born in 1957 or later)
For health care personnel,
(See Notes)
Varicella
(VAR) more info icon.
2 doses (if born in 1980 or later)
2 doses
Zoster recombinant
(RZV) more info icon.
2 doses for immunocompromising conditions
(See Notes)
2 doses
Human papillomavirus
(HPV) more info icon.
2 or 3 doses depending on age at initial vaccination or condition 27 through 45 years
Pneumococcal
(PCV15, PCV20,PCV21, PPSV23) more info icon.
See Notes
See Notes
Hepatitis A
(HepA) more info icon.
2, 3, or 4 doses depending on vaccine
Hepatitis B
(HepB) more info icon.
2, 3, or 4 doses depending on vaccine or condition
Meningococcal A, C, W, Y
(MenACWY) more info icon.
1 or 2 doses depending on indication (See Notes for booster recommendations)
Meningococcal B
(MenB) more info icon.
2 or 3 doses depending on vaccine and indication (See Notes for booster recommendations)
19 through 23 years
Haemophilus influenzae type b
(Hib) more info icon.
1 or 3 doses depending on indication
Mpoxmore info icon. 2 doses
Inactivated poliovirus
(IPV) more info icon.
Complete 3-dose series if incompletely vaccinated. Self–report of previous doses acceptable (See Notes)

To make vaccination recommendations, healthcare providers should:

  1. Determine recommended vaccine by age (Table 1 - By Age)
  2. Assess need for additional recommended vaccinations by medical condition or other indication (Table 2 - By Medical Condition)
  3. Review vaccine types, dosing frequencies and intervals, and considerations for special situations (Notes)
  4. Review contraindications and precautions for vaccine types (Appendix)
  5. Review new or updated ACIP guidance (Addendum)

Additional Information

This schedule is recommended by the Advisory Committee on Immunization Practices  (ACIP) and approved by the Centers for Disease
Control and Prevention (CDC), American College of Physicians (ACP), American Academy of Family Physicians (AAFP), American College of Obstetricians and Gynecologists (ACOG), American College of Nurse-Midwives (ACNM), American Academy of Physician Associates (AAPA), American Pharmacists Association (APhA), and Society for Healthcare Epidemiology of America (SHEA).

Report

  • Suspected cases of reportable vaccine-preventable diseases or outbreaks to your state or local health department
  • Clinically significant adverse events to the Vaccine Adverse Event Reporting System (VAERS) at www.vaers.hhs.gov or (800-822-7967)

Questions or comments
Contact www.cdc.gov/cdc-info or 800-CDC-INFO (800-232-4636), in English or Spanish, 8 a.m.–8 p.m. ET, Monday through Friday, excluding holidays.

Helpful information