NIOSH logo and tagline

4,4'-Methylenedianiline

Related Pages
Synonyms & Trade Names
4,4'-Diaminodiphenylmethane, para, para'-Diaminodiphenyl-methane, Dianilinomethane, 4,4'-Diphenylmethanediamine, MDA
CAS No.
101-77-9
RTECS No.
BY5425000
DOT ID & Guide
Formula
CH₂(C₆H₄NH₂)₂
Conversion
IDLH
Ca [N.D.]
See: IDLH INDEX
Exposure Limits
NIOSH REL
Ca See Appendix A
OSHA PEL
[1910.1050] TWA 0.010 ppm ST 0.100 ppm
Measurement Methods
NIOSH 5029
See: NMAM or OSHA Methods
Physical Description
Pale-brown, crystalline solid with a faint, amine-like odor.
Molecular Weight
198.3
Boiling Point
748°F
Melting Point
198°F
Solubility
0.1%
Vapor Pressure
(77°F): 0.0000002 mmHg
Ionization Potential
10.70 eV
Specific Gravity
1.06 (Liquid at 212°F)
Flash Point
374°F
Upper Explosive Limit
?
Lower Explosive Limit
?
Combustible Solid
Incompatibilities & Reactivities
Strong oxidizers
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes; jaundice, hepatitis; myocardial damage; In Animals: heart, liver, spleen damage; [potential occupational carcinogen]
Target Organs
Eyes, liver, cardiovascular system, spleen
Cancer Site
[in animals: bladder cancer]
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated/Daily
Remove:When wet or contaminated
Change:Daily
Provide:Eyewash, Quick drench
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Soap wash immediately
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

(See Appendix E)

NIOSH

At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter.
Click here for information on selection of N, R, or P filters.
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 1111   MEDICAL TESTS: 0250
Page last reviewed: October 30, 2019
Content source: National Institute for Occupational Safety and Health