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Isophorone diisocyanate

Synonyms & Trade Names
IPDI, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl-isocyanate, Isophorone diamine diisocyanate
CAS No.
4098-71-9
RTECS No.
DOT ID & Guide
2290 156
Formula
C₁₂H₁₈N₂O₂
Conversion
1 ppm = 9.09 mg/m3
IDLH
N.D.
See: IDLH INDEX
Exposure Limits
NIOSH REL
TWA 0.005 ppm (0.045 mg/m3) ST 0.02 ppm (0.180 mg/m3) [skin]
OSHA PEL
none See Appendix G
Measurement Methods
NIOSH 5525;
OSHA PV2034
See: NMAM or OSHA Methods
Physical Description
Colorless to slightly yellow liquid with a pungent odor.
Molecular Weight
222.3
Boiling Point
?
Freezing Point
-76°F
Solubility
Decomposes
Vapor Pressure
0.0003 mmHg
Ionization Potential
?
Specific Gravity
1.06
Flash Point
311°F
Upper Explosive Limit
?
Lower Explosive Limit
?
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities
Water, alcohols, phenols, amines, mercaptans, amides, urethanes, ureas [Note: Reacts with water to form carbon dioxide.]
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, respiratory system; chest tightness, dyspnea (breathing difficulty), cough, sore throat; bronchitis, wheezing, pulmonary edema; possible resp sensitization, asthma
Target Organs
Eyes, skin, respiratory system
Personal Protection/Sanitation
(See protection codes)
Skin:Prevent skin contact
Eyes:Prevent eye contact
Wash skin:When contaminated
Remove:When wet or contaminated
Change:Daily
Provide:Quick drench
First Aid
(See procedures)
Eye:Irrigate immediately
Skin:Water flush immediately
Breathing:Respiratory support
Swallow:Medical attention immediately
Respirator Recommendations

NIOSH

Up to 0.05 ppm:
(APF = 10) Any supplied-air respirator*

Up to 0.125 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*

Up to 0.25 ppm:
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Up to 1 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also
INTRODUCTION   ICSC CARD: 0499
Page last reviewed: October 30, 2019