Voluntary Medical Male Circumcisions for HIV Prevention — 13 Countries in Eastern and Southern Africa, 2017–2021

Weekly / March 10, 2023 / 72(10);256–260

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Megan E. Peck, PhD1; Katherine S. Ong, PhD1; Todd Lucas, MD1; Pauline Harvey, PhD2; Phenyo Lekone, PhD2; Mpho Letebele, MD2; Vasavi T. Thomas, PhD2; Vusi Maziya, MPH3; Mandzisi Mkhontfo, MSPH4; Teruwork Gultie, MSW5; Dejene Mulatu, MPH6; Mesfin Shimelis, MD7; Tiruneh Zegeye, MD7; Ambrose W. Juma, MPH8; Elijah Odoyo-June, PhD9; Paul K. Musingila, MSc9; John Njenga, PhD9; Andrew Auld, MD10; Martin Kapito11; Alice Maida, MD10; Wezi Msungama, MPH10; Marcos Canda, MS12; Jotamo Come, MD13; Inacio Malimane, PhD12; Mekondjo Aupokolo14; Brigitte Zemburuka15; Ida Kankindi, MD16; Samuel Malamba, PhD16; Eric Remera, MSc17; Emmanuel Tubane18; Richard Machava, PhD19; Nandi Maphothi, MSc19; Peter Vranken, MBA19; Mbaraka Amuri, MD20; Kokuhumbya J. Kazaura, DDS20; Daimon Simbeye, MPH20; Stella Alamo, MD21; Geoffrey Kabuye, MD21; Omega Chituwo, MSc22; Royd Kamboyi, MPH23; Joseph Masiye, DCM22; John Mandisarisa, PhD24; Sinokuthemba Xaba, MSc25; Carlos Toledo, PhD1 (View author affiliations)

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Summary

What is already known about this topic?

Voluntary medical male circumcision (VMMC) is associated with an approximately 60% reduction in the risk for female-to-male transmission of HIV. The U.S. President’s Emergency Plan for AIDS Relief, through CDC and other organizations, has supported VMMC for HIV prevention in eastern and southern Africa. During 2010–2016, CDC supported 5,880,372 VMMCs performed in 12 countries.

What is added by this report?

During 2017–2021, CDC supported an additional 8,497,297 VMMCs performed in 13 countries in eastern and southern Africa. Compliance with postoperative follow-up visits within 14 days of VMMC was high, and use of device-based circumcisions remains low.

What are the implications for public health practice?

CDC’s continued support of the VMMC program is a critical component to ending the AIDS epidemic and reaching the Joint United Nations Programme on HIV/AIDS 2025 target of 90% of eligible males having access to VMMC in prioritized countries.

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In 2007, voluntary medical male circumcision (VMMC) was endorsed by the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS after it was found to be associated with approximately a 60% reduction in the risk for female-to-male transmission of HIV (1). As a result of this endorsement, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), through partnerships with U.S. government agencies, including CDC, the U.S. Department of Defense, and the U.S. Agency for International Development, started supporting VMMCs performed in prioritized countries in southern and eastern Africa. During 2010–2016, CDC supported 5,880,372 VMMCs in 12 countries (2,3). During 2017–2021, CDC supported 8,497,297 VMMCs performed in 13 countries. In 2020, the number of VMMCs performed declined 31.8% compared with the number in 2019, primarily because of COVID-19–related disruptions to VMMC service delivery. PEPFAR 2017–2021 Monitoring, Evaluation, and Reporting data were used to provide an update and describe CDC’s contribution to the scale-up of the VMMC program, which is important to meeting the 2025 Joint United Nations Programme on HIV/AIDS (UNAIDS) target of 90% of males aged 15–59 years having access to VMMC services in prioritized countries to help end the AIDS epidemic by 2030 (4).

VMMC programs are incorporated into national HIV prevention portfolios. Services include voluntary HIV testing, HIV risk reduction education, screening and treatment of sexually transmitted infections, and linkage to care and treatment for clients who receive a positive HIV test result. During 2017–2021, CDC supported VMMC programs in 13 countries: Botswana, Eswatini, Ethiopia, Kenya, Malawi, Mozambique, Namibia, Rwanda, South Africa, Tanzania, Uganda, Zambia, and Zimbabwe. Not all of these countries were supported by CDC during the entire 5-year period.*

VMMC programs report indicators to the PEPFAR Monitoring, Evaluation, and Reporting database every quarter in accordance with the U.S. government fiscal year† (5). This analysis includes the annual number of CDC-supported VMMCs performed, as well as the following indicators: client age group, HIV test results among males who underwent testing at VMMC sites, attendance at postoperative follow-up visits within 14 days, and type of circumcision method (use of a WHO pre-qualified circumcision device as method of circumcision or traditional surgical technique). Age was categorized as <15 years, 15–29 years, and ≥30 years. The prevalence of HIV-positivity was calculated by dividing the number of males who received a positive test result for HIV by the number of males who underwent HIV testing at VMMC sites. All statistical analyses were performed using Stata software (version 16; StataCorp). This activity was reviewed by CDC and was conducted consistent with applicable federal law and CDC policy.§

During 2017–2021, CDC supported 8,497,297 VMMCs in 13 countries (Table) (Figure). During 2017–2019, the number of CDC-supported VMMCs increased annually, with a mean annual increase of 13.5%. During 2020, at the start of the COVID-19 pandemic, the number of VMMCs declined 31.8%, from 2,120,797 in 2019 to 1,447,147, with further reductions during 2021. During 2017–2019, 43.8% of all VMMCs were performed in clients aged 10–14 years and 45.7% in clients aged 15–29 years; the proportion performed in clients aged 15–29 years increased to 61.0% during 2020 and to 86.6% during 2021. Most (74.2%) VMMC clients participated in HIV testing services at VMMC sites; this proportion declined from 86.4% in 2017 to 48.7% in 2021. Among the 5,595,239 males who underwent testing for HIV at VMMC sites, 44,745 (0.8%) received a positive result. HIV-positivity ranged from 0.4% in 2020 to 1.2% in 2021.

Among all VMMC clients during 2017–2021, 90.8% returned for a follow-up visit within 14 days. Postoperative follow-up visits increased among all countries from, 86.2% in 2017 to 96.7% in 2021. Two percent (166,475) of all circumcisions were performed using a device; this proportion was highest (3.8%) in 2017, declined annually until 2020, then increased from 1.1% in 2020 to 2.2% in 2021.

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Discussion

Overall, substantial progress has been made in scaling up CDC-supported VMMC programs, with 8,497,297 VMMCs performed during 2017–2021. Increased programmatic experience in VMMC scale-up and the continued prioritization of VMMC by ministries of health and global stakeholders have contributed to this progress. The decreased number of VMMCs performed during 2020 was largely related to mitigation measures implemented to prevent the spread of COVID-19. In addition, in 2020, based on 2015–2018 data showing that certain severe adverse events associated with VMMC, while very rare, were higher among clients aged 10–14 years (2.9 per 100,000 procedures) than among clients aged ≥15 years (1.6 per 100,000 procedures), PEPFAR increased the age eligibility for VMMC to ≥15 years (6). This change in age eligibility likely contributed to the increase in the proportion of VMMCs performed in persons aged 15–29 years during 2020 and 2021.

During 2017–2021, a total of 44,745 males who underwent testing at a VMMC site received a positive HIV test result. VMMC sites serve as an important entry point for HIV testing; without this opportunity, many cases of HIV infection among males might go undiagnosed. The decrease in HIV testing at VMMC sites in 2020 and 2021 was likely due to changes in testing approaches after the 2019 PEPFAR recommendations to provide targeted testing including screening for clients at higher risk for HIV (7). VMMC postoperative follow-up visits increased in all countries during 2017–2021. The percentage of males who returned for a postoperative follow-up visit within 14 days exceeded the recommended 80%, which helped to facilitate timely detection of an adverse event. To reduce the transmission of COVID-19, many countries conducted virtual follow-up visits during 2020. In 2021, PEPFAR supported this approach based on evidence from the scientific literature and programmatic success (8).

VMMC programs can use WHO-prequalified male circumcision devices which typically includes application of a device for removal of the foreskin, as an alternative to traditional surgical circumcision techniques. The overwhelming majority of VMMCs are still performed through conventional surgical methods; the decision to introduce a circumcision device is country-specific, with many programs still piloting use of the devices. Device-based circumcisions declined from 3.8% during 2017 to 1.1% during 2019 and 2020; one factor contributing to the decline might be the lack of programmatic experience to scale up use of the ShangRing device (Wuhu Snnda Medical Treatment Appliance Technology) when practitioners started to phase out the PrePex device (Circ MedTech, Ltd.) during 2016–2018 after reports of tetanus in patients who received VMMC with this device (9). During 2021, more programs scaled up device-based circumcisions, and their use increased to 2.2% from 1.1% during 2020.

The findings in this report are subject to at least three limitations. First, only CDC-supported VMMC results are reported, so the actual number of VMMCs performed might be higher than that reported here. Second, Monitoring, Evaluation, and Reporting data are subject to reporting and data entry errors. Finally, the data used for this analysis cannot be used to directly assess progress towards reaching the goal of 90% of eligible males having access to VMMC services.

Modeling analyses have estimated that the 26.8 million PEPFAR-supported VMMCs performed during 2008–2019 in prioritized countries have helped prevent 340,000 new HIV infections; this estimate is projected to increase to 1.8 million by 2030, given that VMMC provides a lifelong reduction in HIV risk (10). CDC’s continued support of the VMMC program is a critical component of ending the AIDS epidemic and reaching the UNAIDS 2025 target of 90% of eligible males having access to VMMC in prioritized countries (4). Prioritization of uncircumcised males living in areas of high HIV incidence and those at highest risk for HIV can maximize VMMC’s contribution to HIV epidemic control.

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Corresponding author: Megan E. Peck, okv4@cdc.gov.

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1Divison of Global HIV and Tuberculosis, Center for Global Health, CDC; 2Division of Global HIV and Tuberculosis, CDC Botswana; 3Ministry of Health, Mbabane, Eswatini; 4Division of Global HIV and Tuberculosis, CDC Eswatini; 5ICAP, Addis Ababa, Ethiopia; 6Ministry of Health, Addis Ababa, Ethiopia; 7Division of Global HIV and Tuberculosis, CDC Ethiopia; 8National STD/AIDS Control Program, Ministry of Health, Nairobi, Kenya; 9Division of Global HIV and Tuberculosis, CDC Kenya; 10Division of Global HIV and Tuberculosis, CDC Malawi; 11Ministry of Health, Lilongwe, Malawi; 12Division of Global HIV and Tuberculosis, CDC Mozambique; 13Ministry of Health, Maputo, Mozambique; 14Ministry of Health and Social Services, Windhoek, Namibia; 15Division of Global HIV and Tuberculosis, CDC Namibia; 16Division of Global HIV and Tuberculosis, CDC Rwanda; 17Rwanda Biomedical Centre, Kigali, Rwanda; 18Ministry of Health, Kigali, Rwanda; 19Division of Global HIV and Tuberculosis, CDC South Africa; 20Division of Global HIV and Tuberculosis, CDC Tanzania; 21Division of Global HIV and Tuberculosis, CDC Uganda; 22Division of Global HIV and Tuberculosis, CDC Zambia; 23Ministry of Health, Lusaka, Zambia; 24Division of Global HIV and Tuberculosis, CDC Zimbabwe; 25Ministry of Health and Child Care, Harare, Zimbabwe.

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All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

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* Eswatini started receiving CDC support in 2019, and in 2020 Namibia shifted PEFPAR support from CDC to another U.S. government agency.

† Years in VMMC program data refer to U.S. government fiscal years (October 1–September 30).

§ 45 C.F.R. part 46, 21 C.F.R. part 56; 42 U.S.C. Sect. 241(d); 5 U.S.C. Sect. 552a; 44 U.S.C. Sect. 3501 et seq.

Rwanda and Tanzania stopped reporting HIV testing rates in fiscal year 2020 because of a change in funding and testing practices at VMMC sites.

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References

  1. World Health Organization. New data on male circumcision and HIV prevention: policy and programme implications. Geneva, Switzerland: World Health Organization; 2007. https://www.who.int/publications/i/item/9789241595988
  2. Hines JZ, Ntsuape OC, Malaba K, et al. Scale-up of voluntary medical male circumcision services for HIV prevention—12 countries in southern and eastern Africa, 2013–2016. MMWR Morb Mortal Wkly Rep 2017;66:1285–90 . https://doi.org/10.15585/mmwr.mm6647a2 PMID:29190263
  3. CDC. Voluntary medical male circumcision—southern and eastern Africa, 2010–2012. MMWR Morb Mortal Wkly Rep 2013;62:953–7. PMID:24280914
  4. Joint United Nations Programme on HIV/AIDS. Prevailing against pandemics by putting people at the centre—World AIDS Day report 2020. Geneva, Switzerland: Joint United Nations Programme on HIV/AIDS; 2020. https://www.unaids.org/en/resources/documents/2020/prevailing-against-pandemics
  5. Davis SM, Hines JZ, Habel M, et al. Progress in voluntary medical male circumcision for HIV prevention supported by the US President’s Emergency Plan for AIDS Relief through 2017: longitudinal and recent cross-sectional programme data. BMJ Open 2018;8:e021835 . https://doi.org/10.1136/bmjopen-2018-021835 PMID:30173159
  6. US President’s Emergency Plan for AIDS Relief. PEPFAR 2020 country operational plan guidance for all PEPFAR countries. Washington, DC: US President’s Emergency Plan for AIDS Relief; 2020. https://www.state.gov/wp-content/uploads/2020/01/COP20-Guidance.pdf
  7. US President’s Emergency Plan for AIDS Relief. PEFPAR 2019 country operational plan guidance for all PEPFAR countries. Washington, DC: US President’s Emergency Plan for AIDS Relief; 2019. https://www.state.gov/wp-content/uploads/2019/08/PEPFAR-Fiscal-Year-2019-Country-Operational-Plan-Guidance.pdf
  8. US President’s Emergency Plan for AIDS Relief. PEPFAR 2022 country and regional operational plan (COP/ROP) guidance for all PEPFAR-supported countries. Washington, DC: US President’s Emergency Plan for AIDS Relief; 2021. https://www.state.gov/wp-content/uploads/2022/01/COP22-Guidance-Final_508-Compliant.pdf
  9. Grund JM, Toledo C, Davis SM, et al. Notes from the field: tetanus cases after voluntary medical male circumcision for HIV prevention—eastern and southern Africa, 2012–2015. MMWR Morb Mortal Wkly Rep 2016;65:36–7 . https://doi.org/10.15585/mmwr.mm6502a5 PMID:26797167
  10. Joint United Nations Programme on HIV/AIDS. Voluntary medical male circumcision. Geneva, Switzerland: Joint United Nations Programme on HIV/AIDS; 2021. https://hivpreventioncoalition.unaids.org/wp-content/uploads/2021/04/JC3022_VMMC_4-pager_En_v3.pdf

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TABLE. CDC-supported voluntary medical male circumcisions — 13 countries in eastern and southern Africa, 2017–2021Return to your place in the text
Country Fiscal year* No. of VMMCs performed Annual target achieved, % Client age group, yrs, no. (%) No. (%)
<15 15–29 ≥30 VMMCs performed using a device† Clients who received HIV testing at a VMMC site Clients with a positive HIV test result§ Clients with postoperative follow-up within 14 days of VMMC
Botswana 2017 17,870 117.0 11,205 (62.7) 4,814 (26.9) 1,851 (10.4) 287 (1.6) 9,311 (52.1) 14 (0.2) 10,968 (61.4)
2018 15,874 76.0 9,386 (59.1) 4,701 (29.6) 1,787 (11.3) 0 (—) 7,730 (48.7) 29 (0.4) 14,674 (92.4)
2019 16,461 78.4 7,710 (46.8) 6,127 (37.2) 2,624 (15.9) 0 (—) 9,436 (57.3) 11 (0.1) 16,155 (98.1)
2020 5,845 28.0 2,313 (39.7) 2,252 (38.6) 1,265 (21.7) 0 (—) 3,913 (66.9) 20 (0.5) 5,514 (94.3)
2021 2,748 31.0 0 (—)** 1,539 (35.9) 2,748 (64.1) 0 (—) 1,437 (52.3) 25 (1.7) 2,720 (99.0)
Total 58,798 67.4 30,614 (50.8) 19,433 (32.2) 10,275 (17.0) 287 (0.5) 31,827 (54.1) 99 (0.3) 50,031 (85.1)
Eswatini 2017†† 0 0 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—)
2018†† 0 0 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—)
2019 761 20.0 298 (39.2) 410 (53.9) 53 (7.0) 0 (—) 707 (92.9) 7 (1.0) 761 (100.0)
2020 4,626 24.0 1,923 (41.6) 2,197 (47.5) 506 (10.9) 0 (—) 4,245 (91.8) 56 (1.3) 4,322 (93.4)
2021 3,269 79.2 3 (0.1)** 2,561 (78.3) 705 (21.6) 0 (—) 2,984 (91.3) 6 (0.2) 3,259 (99.7)
Total 8,656 31.5 2,224 (25.7) 5,168 (59.7) 1,264 (14.6) 0 (—) 7,936 (91.7) 69 (0.9) 8,342 (96.4)
Ethiopia 2017 10,910 96.2 5,290 (48.5) 4,610 (42.3) 1,010 (9.3) 0 (—) 8,149 (74.7) 3 (0.0) 10,905 (99.9)
2018 20,302 112.0 9,023 (44.4) 9,312 (45.9) 1,967 (9.7) 0 (—) 13,941 (68.7) 43 (0.3) 19,874 (97.9)
2019 23,776 98.3 10,024 (42.2) 11,768 (49.5) 1,984 (8.3) 0 (—) 21,907 (92.1) 7 (0.0) 23,169 (97.4)
2020 33,483 82.1 3,198 (9.6) 25,681 (76.7) 4,604 (13.8) 0 (—) 31,189 (93.1) 30 (0.1) 32,540 (97.2)
2021 45,499 101.1 0 (—)** 39,148 (86.0) 6,351 (14.0) 0 (—) 23,417 (51.5) 14 (0.1) 44,636 (98.1)
Total 133,970 96.1 27,535 (20.6) 90,519 (67.6) 15,916 (11.9) 0 (—) 98,603 (73.6) 97 (0.1) 131,124 (97.9)
Kenya 2017 149,286 90.7 106,754 (71.5) 38,858 (26.0) 3,674 (2.5) 1,446 (1.0) 146,157 (97.9) 285 (0.2) 121,855 (81.6)
2018 191,111 96.5 158,642 (83.0) 29,540 (15.5) 2,929 (1.5) 2,140 (1.1) 82,772 (43.3) 281 (0.3) 159,537 (83.5)
2019 185,145 93.9 161,990 (87.5) 20,405 (11.0) 2,750 (1.5) 2,820 (1.5) 24,346 (13.1) 64 (0.3) 170,353 (92.0)
2020 68,173 48.8 45,030 (66.1) 21,366 (31.4) 1,708 (2.5) 1,750 (2.6) 14,823 (21.7) 25 (0.2) 60,432 (88.6)
2021 25,351 115.6 1 (0)** 22,803 (89.9) 2,547 (10.0) 2,789 (11.0) 7,671 (30.3) 16 (0.2) 24,683 (97.4)
Total 619,066 85.8 472,417 (79.2) 110,169 (18.5) 13,608 (2.3) 10,945 (1.8) 275,769 (44.5) 671 (0.2) 536,860 (86.7)
Malawi 2017 30,136 86.1 5,612 (18.6) 21,455 (71.2) 3,069 (10.2) 0 (—) 30,063 (99.8) 104 (0.3) 24,219 (80.4)
2018 46,004 92.0 4,199 (9.1) 37,562 (81.6) 4,243 (9.2) 109 (0.2) 45,780 (99.5) 520 (1.1) 37,216 (80.9)
2019 52,062 104.1 3,205 (6.2) 45,015 (86.5) 3,842 (7.4) 824 (1.6) 51,791 (99.5) 434 (0.8) 52,041 (99.9)
2020 34,239 38.9 4,423 (12.9) 27,677 (80.8) 2,139 (6.2) 371 (1.1) 28,482 (83.2) 14 (0.0) 34,239 (99.9)
2021 70,178 97.5 0 (—)** 65,226 (92.9) 4,952 (7.1) 5,667 (8.1) 23,429 (33.4) 25 (0.1) 69,961 (99.7)
Total 232,619 78.8 17,439 (8.1) 196,935 (91.9) 18,245 (8.5) 6,971 (3.0) 179,545 (77.2) 1,097 (0.6) 217,676 (93.6)
Mozambique 2017 189,225 62.5 96,218 (50.8) 83,211 (44.0) 9,796 (5.2) 0 (—) 178,615 (94.4) 4,350 (2.4) 144,708 (76.5)
2018 233,069 90.9 131,881 (56.6) 90,365 (38.8) 10,823 (4.6) 0 (—) 219,906 (94.4) 4,530 (2.1) 200,060 (85.8)
2019 222,887 83.1 130,731 (58.7) 82,253 (36.9) 9,903 (4.4) 0 (—) 206,983 (92.9) 4,736 (2.3) 193,267 (86.7)
2020 120,464 42.9 59,232 (49.2) 54,596 (45.3) 6,636 (5.5) 0 (—) 57,490 (47.7) 1,109 (1.9) 98,738 (82.0)
2021 46,292 84.3 0 (—)** 37,873 (81.8) 8,419 (18.2) 0 (—) 31,419 (67.9) 3,183 (10.1) 39,549 (85.4)
Total 811,937 69.8 418,062 (51.5) 348,298 (42.9) 45,577 (5.6) 0 (—) 694,413 (85.5) 17,908 (2.6) 676,322 (83.3)
Namibia 2017 15,579 70.1 5,037 (33.0) 7,937 (51.9) 2,305 (15.0) 0 (—) 9,377 (60.2) 63 (0.7) 15,106 (97.0))
2018 19,384 82.7 8,807 (46.0) 8,393 (43.8) 1,957 (10.2) 0 (—) 9,752 (50.3) 36 (0.4) 18,857 (97.3)
2019 17,059 73.3 7,480 (45.5) 7,235 (44.0) 1,711 (10.4) 546 (3.2) 8,829 (51.8) 44 (0.5) 15,614 (91.5)
2020¶,†† 0 0 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—)
2021†† 0 0 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—) 0 (—)
Total 52,022 75.4 21,324 (41.9) 23,565 (46.3) 5,973 (11.7) 546 (1.0) 27,958 (53.7) 143 (0.5) 49,577 (95.3)
Rwanda 2017 91,689 191.2 25,123 (27.4) 63,301 (69.1) 3,245 (3.5) 53,351 (58.2) 90,564 (98.8) 281 (0.3) 91,662 (99.9)
2018 75,338 222.2 28,866 (38.3) 43,323 (57.5) 3,149 (4.2) 30,178 (40.1) 68,384 (90.8) 22 (0.0) 75,201 (99.8)
2019 79,622 152.6 23,933 (30.1) 52,202 (65.6) 3,487 (4.4) 15,167 (19.0) 44,729 (56.2) 14 (0.0) 79,420 (99.7)
2020 140,984 143.2 35,383 (25.1) 100,287 (71.1) 5,314 (3.8) 7,615 (5.4) 0 (—)§§ 0 (—)§§ 140,784 (99.9)
2021 181,539 156.4 14 (0)** 163,800 (90.2) 17,725 (9.8) 2,016 (1.1) 0 (—)§§ 0 (—)§§ 179,435 (98.9)
Total 569,172 163.3 113,319 (19.9) 422,916 (74.3) 32,920 (5.8) 108,327 (19.0) 203,677 (35.8) 317 (0.2) 566,502 (99.5)
South Africa 2017 232,198 94.3 91,312 (39.3) 114,436 (49.3) 26,450 (11.4) 886 (0.4) 140,960 (60.7) 4,390 (3.1) 169,955 (73.2)
2018 284,202 81.7 144,208 (50.8) 107,826 (38.0) 32,037 (11.3) 0 (—) 260,025 (91.5) 4,524 (1.7) 189,787 (66.8)
2019 332,096 109.1 125,598 (38.0) 175,228 (53.0) 30,055 (9.1) 0 (—) 285,267 (85.9) 1,795 (0.6) 247,819 (74.6)
2020 144,622 46.4 34,347 (23.7) 89,195 (61.7) 21,080 (14.6) 0 (—) 134,101 (92.7) 412 (0.3) 131,951 (91.2)
2021 164,995 52.4 0 (—)** 113,625 (68.9) 51,369 (31.1) 0 (—) 142,756 (86.5) 1,068 (0.7) 152,267 (92.3)
Total 1,158,113 75.9 395,465 (34.2) 600,310 (51.9) 160,991 (13.9) 886 (0.1) 1,022,493 (88.3) 14,189 (1.4) 891,779 (77.0)
Tanzania 2017 290,041 91.7 131,039 (45.2) 136,000 (46.9) 23,002 (7.9) 0 (—) 222,693 (76.8) 547 (0.2) 258,342 (89.1)
2018 451,073 92.8 206,288 (45.7) 209,371 (46.4) 35,414 (7.9) 0 (—) 450,318 (99.8) 674 (0.1) 390,295 (86.5)
2019 453,764 110.4 193,883 (42.7) 223,742 (49.3) 36,139 (8.0) 1,517 (0.3) 59,909 (13.2) 105 (0.2) 438,954 (96.7)
2020 299,967 104.4 140,485 (46.8) 140,580 (46.9) 18,902 (6.3) 817 (0.3) 0 (—)§§ 0 (—)§§ 296,017 (98.7)
2021 337,989 95.9 0 (—)** 304,264 (90.0) 33,725 (10.0) 0 (—) 0 (—)§§ 0 (—)§§ 334,933 (99.1)
Total 1,832,834 98.9 671,695 (39.3) 891,557 (52.1) 147,182 (8.6) 2,334 (0.1) 732,920 (40.0) 1,326 (0.2) 1,718,541 (93.8)
Uganda 2017 334,515 71.5 68,104 (33.2) 119,705 (58.4) 17,175 (8.4) 1,590 (0.5) 310,211 (92.7) 1,324 (0.4) 296,092 (88.5)
2018 340,168 100.1 144,585 (49.4) 128,088 (43.8) 20,029 (6.8) 134 (0.0) 319,255 (93.9) 5,422 (1.7) 321,776 (94.6)
2019 336,947 98.1 140,769 (41.8) 168,459 (50.0) 27,603 (8.2) 399 (0.1) 283,062 (84.0) 612 (0.2) 321,085 (95.3)
2020 291,955 73.2 65,981 (22.6) 193,944 (66.4) 32,030 (11.0) 925 (0.3) 227,315 (77.9) 497 (0.2) 284,636 (97.5)
2021 153,534 103.0 544 (0.4) 132,983 (86.6) 20,007 (13.0) 7,627 (5.0) 89,554 (58.3) 284 (0.3) 143,644 (93.6)
Total 1,457,119 85.8 419,983 (31.0) 743,179 (54.9) 116,844 (8.6) 10,675 (0.7) 1,229,397 (84.4) 8,139 (0.7) 1,367,233 (93.8)
Zambia 2017 181,767 171.4 68,397 (37.6) 97,113 (53.4) 16,237 (8.9) 477 (0.3) 173,555 (95.5) 824 (0.5) 175,361 (96.5)
2018 173,425 128.2 48,704 (28.1) 109,385 (63.1) 15,328 (8.8) 391 (0.2) 170,722 (98.4) 482 (0.3) 162,355 (94.0)
2019 271,099 167.7 67,514 (24.9) 176,690 (65.2) 26,852 (9.9) 2,371 (0.9) 226,737 (83.6) 570 (0.3) 259,892 (95.9)
2020 240,857 126.9 31,032 (12.9) 188,853 (78.4) 20,972 (8.7) 4,738 (2.0) 66,969 (27.8) 91 (0.1) 233,739 (97.0)
2021 282,259 139.0 0 (—)** 258,048 (91.4) 24,211 (8.6) 12,217 (4.3) 39,859 (14.1) 71 (0.2) 276,061 (97.8)
Total 1,149,407 144.4 215,647 (18.8) 830,089 (72.2) 103,600 (9.0) 20,194 (1.8) 677,842 (59.0) 2,038 (0.3) 1,107,408 (96.3)
Zimbabwe 2017 103,677 103.7 43,383 (41.9) 51,357 (49.5) 8,914 (8.6) 5,037 (4.9) 103,546 (99.9) 270 (0.3) 99,821 (96.3)
2018 70,494 66.7 24,026 (34.1) 39,383 (55.9) 7,083 (10.0) 0 (—) 70,454 (99.9) 111 (0.2) 64,721 (91.8)
2019 129,118 102.7 42,994 (33.3) 72,084 (55.9) 13,966 (10.8) 52 (0.0) 129,044 (99.9) 119 (0.1) 124,692 (96.6)
2020 61,932 48.0 20,059 (32.4) 35,674 (57.6) 6,199 (10.0) 0 (—) 61,880 (99.9) 86 (0.1) 59,796 (96.6)
2021 48,363 37.1 0 (—)** 39,042 (80.7) 9,321 (19.3) 221 (0.5) 47,935 (99.1) 73 (0.2) 45,513 (94.1)
Total 413,584 70.0 130,462 (31.6) 237,540 (57.4) 45,483 (11.0) 5,310 (1.3) 412,859 (99.8) 659 (0.2) 394,543 (95.4)
All countries 2017 1,646,893 89.7 657,474 (43.3) 742,797 (49.0) 116,728 (7.7) 63,074 (3.8) 1,423,201 (86.4) 12,455 (0.9) 1,418,994 (86.2)
2018 1,920,444 95.3 918,615 (49.1) 817,249 (43.6) 136,746 (7.3) 32,952 (1.7) 1,719,039 (89.5) 16,674 (1.0) 1,654,353 (86.1)
2019 2,120,797 106.8 916,129 (43.2) 1,041,618 (49.2) 160,969 (7.6) 23,696 (1.1) 1,352,040 (63.8) 8,511 (0.6) 1,942,461 (91.6)
2020 1,447,147 72.2 443,406 (30.6) 882,302 (61.0) 121,355 (8.4) 16,216 (1.1) 630,407 (62.7)§§ 2,340 (0.4) 1,382,708 (95.5)
2021 1,362,016 92.5 562 (0) 1,180,912 (86.6) 182,080 (13.4) 30,537 (2.2) 410,461 (48.7)§§ 4,765 (1.2) 1,316,661 (96.7)
Total 8,497,297 91.2 2,936,186 (35.3) 4,664,878 (56.1) 717,082 (8.6) 166,475 (2.0) 5,595,239 (74.2) §§ 44,745 (0.8) 7,715,177 (90.8)

Abbreviations: PEPFAR = U.S. President’s Emergency Plan for AIDS Relief; VMMC = voluntary medical male circumcision.
* October 1–September 30.
† VMMCs performed using a device refers to use of World Health Organization–prequalified circumcision device as method of circumcision instead of traditional surgical technique.
§ HIV prevalence was calculated by dividing the number of males who received positive HIV test results by the number undergoing HIV testing services at VMMC sites.
COVID-19 was declared a pandemic in 2020.
** In 2021 most countries reported zero or a small number of VMMCs conducted in clients aged <15 years because of a change in VMMC age eligibility to 15 years with the exception of the ShangRing device (Wuhu Snnda Medical Treatment Appliance Technology).
†† Eswatini in 2017 and 2018 and Namibia in 2020 and 2021 did not have a CDC-supported VMMC program.
§§ Rwanda and Tanzania stopped conducting PEPFAR-supported HIV testing at VMMC sites in 2020 and 2021. These countries were excluded from the combined country estimates.

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Return to your place in the textFIGURE. CDC-supported voluntary medical male circumcisions, by year — 13 eastern and southern African countries, 2017–2021*
The figure is a stacked bar chart showing CDC-supported voluntary medical male circumcisions, by year, in 13 eastern and southern African countries during 2017–2021.

* COVID-19 was declared a pandemic in 2020.

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Suggested citation for this article: Peck ME, Ong KS, Lucas T, et al. Voluntary Medical Male Circumcisions for HIV Prevention — 13 Countries in Eastern and Southern Africa, 2017–2021. MMWR Morb Mortal Wkly Rep 2023;72:256–260. DOI: http://dx.doi.org/10.15585/mmwr.mm7210a2.

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