Key points
- Most people who get hepatitis A have a mild, short-term illness.
- Adults are more likely than children to have symptomatic HAV infection.
- Clinicians should conduct serologic testing on patients if they have signs or symptoms consistent with HAV infection.
- CDC does not recommend routine hepatitis A screening.
Disease presentation
Older children and adults with HAV infection will typically experience symptoms.
Most (70%) of infections in children younger than age 6 are not accompanied by symptoms. When symptoms are present, young children typically do not have jaundice; most (>70%) older children and adults with HAV infection have jaundice. 12
Among symptomatic patients, 10%–15% might experience prolonged or relapsing symptoms up to 6 months after they become infected.13456
Incubation period
The average incubation period for HAV is 28 days (range: 15–50 days).345
Virus survival
Depending on the environmental conditions, the virus can live outside the body for months.6
For the public
Common symptoms
Hepatitis A symptoms, which usually last less than 2 months, occur abruptly, and can include:
- Abdominal pain, nausea, and/or vomiting
- Dark urine or clay-colored stools
- Diarrhea
- Fatigue
- Fever
- Jaundice
- Joint pain
- Loss of appetite
For detailed guidance on clinical care and treatment for hepatitis A, keep reading.
- Wasley A, Fiore A, Bell BP. Hepatitis A in the era of vaccination. Epidemiol Rev 2006;28:101–11. Epub 2006 Jun 14. Review.
- Schiff ER. Atypical clinical manifestations of hepatitis A. Vaccine 1992;10 Suppl 1:S18.
- Halliday ML, Kang LY, Zhou TK, et al. An epidemic of hepatitis A attributable to the ingestion of raw clams in Shanghai, China. J Infect Dis 1991;164(5):852–9.
- Neefe JR, Gellis SS, Stokes J Jr. Homologous serum hepatitis and infectious (epidemic) hepatitis: studies in volunteers bearing on immunological and other characteristics of the etiological agents. Am J Med 1946;1:3–22.
- Krugman S, Giles JP, Hammond J. Infectious hepatitis: Evidence for two distinctive clinical, epidemiological, and immunological types of infection. JAMA 1967;200(5):365–73.
- Abad FX, Pinto RM, Bosch A. Survival of enteric viruses on environmental fomites. Appl Environ Microbiol 1994;60(10):3704–10.