Table of Contents

About

  • This ACIP GRADE handbook provides guidance to the ACIP workgroups on how to use the GRADE approach for assessing the certainty of evidence.

Index

Chapter 1: Introduction
Learn more about the history and purpose of the U.S. Advisory Committee on Immunization Practices (A...
Chapter 2: Creating Trustworthy Guidelines
To learn more about how to create more trusting guidelines using the eight steps outlined.
Chapter 3: Overview of the Guideline Development Process
Learn more about ACIP's overview of the guideline development process.
Chapter 4: Formulating PICO Questions
To learn more about how to formulate Population, Intervention, Comparator, Outcomes questions.
Chapter 5: Choosing and Ranking Outcomes
To learn more about developing PICO questions by choosing and ranking outcomes.
Chapter 6: Systematic Review Overview
To learn more about ACIP's systematic review process.
Chapter 7: GRADE Criteria Determining Certainty of Evidence
Learn more about the GRADE criteria and how to determine certainty of evidence.
Chapter 8: Domains Decreasing Certainty in the Evidence
To learn more about the domains decreasing certainty in the evidence in ACIP recommendations.
Chapter 9: Domains Increasing One’s Certainty in the Evidence
Learn more about the domains in increasing one's certainty in evidence.
Chapter 10: Overall Certainty of Evidence
To learn more about the overall certainty of evidence.
Chapter 11: Communicating Findings from the GRADE Certainty Assessment
To learn more about how to communicate findings from the GRADE certainty assessment.
Chapter 12: Integrating Randomized and Non-randomized Studies in Evidence Synthesis
To learn more about integrating randomized and non-randomized studies in evidence synthesis.
Print
Content Source:
National Center for Immunization and Respiratory Diseases (NCIRD)