Table 2.8. Number and rates* of deaths with hepatitis B virus infections listed as a cause of death among residents, by demographic characteristics — United States, 2015–2019

Table 2.8. Number and rates* of deaths with hepatitis B virus infections listed as a cause of death† among residents, by demographic characteristics — United States, 2015–2019
Table 2.8.
Characteristic 2015 No. 2015 Rate*
(95% CI)
2016 No. 2016 Rate*
(95% CI)
2017 No. 2017 Rate*
(95% CI)
2018 No. 2018 Rate*
(95% CI)
2019 No. 2019 Rate*
(95% CI)
Total 1,707 0.46
(0.44-0.49)
1,690 0.45
(0.43-0.48)
1,727 0.46
(0.44-0.49)
1,649 0.43
(0.41-0.45)
1,662 0.42
(0.40-0.44)
Age group (years)
0-34 30 0.02
(0.01- 0.03)
39 0.03
(0.02-0.04)
29 0.02
(0.01-0.03)
32 0.02
(0.01-0.03)
45 0.03
(0.02-0.04)
35-44 118 0.29
(0.24-0.34)
116 0.29
(0.23-0.34)
106 0.26
(0.21-0.31)
122 0.30
(0.24-0.35)
110 0.26
(0.21-0.31)
44-54 330 0.76
(0.68-0.85)
324 0.76
(0.67-0.84)
323 0.76
(0.68-0.85)
283 0.68
(0.60-0.76)
255 0.62
(0.55-0.70)
55-64 610 1.49
(1.37-1.61)
576 1.39
(1.28-1.50)
548 1.30
(1.20-1.41)
520 1.23
(1.12-1.34)
502 1.18
(1.08-1.29)
65-74 382 1.39
(1.25-1.53)
383 1.34
(1.20-1.47)
417 1.40
(1.27-1.54)
422 1.38
(1.25-1.52)
484 1.54
(1.40-1.67)
≥75 236 1.17
(1.02-1.32)
252 1.22
(1.07-1.37)
303 1.43
(1.27-1.59)
270 1.23
(1.08-1.38)
266 1.18
(1.04-1.32)
Sex
Male 1,270 0.70
(0.66-0.74)
1,231 0.67
(0.64-0.71)
1,275 0.70
(0.66-0.74)
1,191 0.65
(0.61-0.69)
1,248 0.66
(0.62-0.70)
Female 437 0.21
(0.19-0.23)
459 0.22
(0.20-0.24)
452 0.23
(0.20-0.25)
458 0.22
(0.20-0.24)
414 0.21
(0.19-0.24)
Race/ethnicity
White, non-Hispanic 805 0.28
(0.26-0.30)
767 0.29
(0.27-0.31)
776 0.28
(0.26-0.30)
760 0.27
(0.25-0.29)
761 0.28
(0.26-0.30)
Black, non-Hispanic 318 0.75
(0.67-0.84)
315 0.73
(0.65-0.81)
320 0.74
(0.66-0.83)
304 0.70
(0.62-0.79)
291 0.64
(0.56-0.71)
Hispanic 136 0.32
(0.27-0.38)
128 0.30
(0.25-0.36)
109 0.26
(0.21-0.32)
122 0.28
(0.23-0.33)
117 0.27
(0.21-0.32)
Asian/Pacific Islander 419 2.23
(2.01-2.45)
454 2.38
(2.16-2.60)
492 2.45
(2.23-2.67)
439 2.10
(1.90-2.30)
463 2.10
(1.90-2.29)
American Indian/Alaska Native 13 UR§ 16 UR§ 17 UR§ 6 UR§ 20 0.76
(0.46-1.18)
HHS Region: Regional Office ¶
Region 1: Boston 81 0.43
(0.34-0.54)
56 0.28
(0.21-0.37)
60 0.35
(0.27-0.46)
64 0.34
(0.26-0.45)
43 0.22
(0.16-0.30)
Region 2: New York 163 0.48
(0.41-0.56)
177 0.51
(0.43-0.59)
166 0.47
(0.39-0.54)
156 0.44
(0.36-0.51)
147 0.42
(0.35-0.49)
Region 3: Philadelphia 126 0.35
(0.28-0.41)
118 0.32
(0.26-0.38)
128 0.32
(0.27-0.38)
130 0.35
(0.29-0.41)
126 0.32
(0.26-0.38)
Region 4: Atlanta 328 0.43
(0.38-0.48)
345 0.44
(0.39-0.49)
365 0.45
(0.41-0.50)
346 0.45
(0.40-0.50)
348 0.42
(0.38-0.47)
Region 5: Chicago 193 0.32
(0.27-0.36)
181 0.29
(0.25-0.33)
184 0.29
(0.24-0.33)
174 0.28
(0.24-0.33)
173 0.27
(0.23-0.31)
Region 6: Dallas 220 0.50
(0.43-0.56)
230 0.51
(0.44-0.57)
247 0.55
(0.48-0.62)
230 0.47
(0.41-0.53)
230 0.48
(0.42-0.55)
Region 7: Kansas City 44 0.26
(0.19-0.36)
52 0.33
(0.24-0.44)
50 0.29
(0.22-0.39)
65 0.38
(0.29-0.48)
51 0.30
(0.22-0.40)
Region 8: Denver 42 0.35
(0.25-0.47)
35 0.27
(0.19-0.38)
48 0.37
(0.27-0.49)
34 0.25
(0.17-0.35)
47 0.32
(0.23-0.43)
Region 9: San Francisco 416 0.72
(0.65-0.79)
415 0.73
(0.66-0.80)
393 0.69
(0.62-0.76)
369 0.62
(0.56-0.69)
394 0.64
(0.57-0.70)
Region 10: Seattle 94 0.56
(0.45-0.69)
81 0.51
(0.40-0.63)
86 0.52
(0.41-0.64)
81 0.47
(0.37-0.59)
103 0.58
(0.47-0.70)
Source: CDC, National Center for Health Statistics, Multiple Cause of Death 1999–2019 on CDC WONDER Online Database. Data are from the 2015–2019 Multiple Cause of Death files and are based on information from all death certificates filed in the vital records offices of the 50 states and the District of Columbia through the Vital Statistics Cooperative Program. Deaths of nonresidents (e.g., nonresident aliens, nationals living abroad, residents of Puerto Rico, Guam, the Virgin Islands, and other US territories) and fetal deaths are excluded. Numbers are slightly lower than previously reported for 2015–2016 because of NCHS standards that restrict displayed data to US residents. Accessed at http://wonder.cdc.gov/mcd-icd10.html on January 8, 2021. CDC WONDER data set documentation and technical methods can be accessed at https://wonder.cdc.gov/wonder/help/mcd.html#.
* Rates for race/ethnicity, sex, HHS region, and the overall total are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): <1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and ≥85. For age-adjusted death rates, the age-specific death rate is rounded to 1 decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths. Missing data are not included.
† Cause of death is defined as 1 of the multiple causes of death and is based on the International Classification of Diseases, 10th Rev (ICD-10) codes B16, B17.0, B18.0, B18.1 (hepatitis B).
UR§ Unreliable rate: Rates where death counts were <20 were not displayed because of the instability associated with those rates.
¶ US Department of Health and Human Services (HHS) regions were categorized according to the grouping of states and US territories assigned under each of the 10 HHS regional offices (https://www.hhs.gov/about/agencies/iea/regional-offices/index.html). For the purposes of this report, regions with US territories (Regions 2 and 9) contain data from states only.
For the purposes of this report, regions with US territories (Regions 2 and 9) contain data from states only.

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This table summarizes the characteristics of hepatitis B-associated deaths among residents in the United States. During 2019, a total of 1,662 hepatitis B-associated deaths among US residents were reported in the US Multiple Cause of Death data from the National Center for Health Statistics, which corresponds to an age-adjusted death rate of 0.42 cases per 100,000 population. This US age-adjusted death rates have been relatively consistent during 2015–2019. The mortality rate was highest among Asian/Pacific Islander persons (2.10 deaths per 100,000 population), approximately 7.5 times the rate among non-Hispanic White persons. The hepatitis B-associated mortality rates were also higher than the national rate among adults aged ≥45 years, males, and in Health and Human Services Regions 9 (Arizona, California, Hawaii, and Nevada) and 10 (Alaska, Idaho, Oregon, and Washington).

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