TB Clusters by Size: 2022–2024

About

This table reports the number of cases of tuberculosis (TB) disease and whole-genome multilocus sequence type (wgMLSType) clusters by cluster size during 2022-2024.

Key Highlights

  • During 2022–2024, there were 1,268 TB clusters involving 3,794 cases.
  • Clusters of 2 or 3 cases comprised 85% of all clusters.
  • There were 33 large clusters (≥10 cases) that represented 3% of all clusters and contained 599 cases (16% of all clustered cases).

Data Table

Tuberculosis Cases and wgMLSType Clusters by Cluster Size:1 United States, 2022–2024

CDC reports the number of cases and clusters of TB disease in the United States during 2022-2024.
Cluster size Clusters Cases2
No. (%)3 No. (%)4
Total 1,268 (100.0) 3,794 (100.0)
2 case cluster 874 (68.9) 1,748 (46.1)
3 case cluster 210 (16.6) 630 (16.6)
4 case cluster 62 (4.9) 248 (6.5)
5 case cluster 32 (2.5) 160 (4.2)
6 case cluster 21 (1.7) 126 (3.3)
7 case cluster 13 (1.0) 91 (2.4)
8 case cluster 15 (1.2) 120 (3.2)
9 case cluster 8 (0.6) 72 (1.9)
≥10 case cluster5 33 (2.6) 599 (15.8)

1Clusters have two or more cases with matching whole-genome multilocus sequence type (wgMLSType).

2Cases with matching wgMLSType are members of a cluster within a county during the specified 3-year time period.

3Percentages calculated based on the total number of clusters.

4Percentages calculated based on the total number of cases.

Notes

Data for all years are updated through July 10, 2025.