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Variant Influenza: Information for Health Professionals and Laboratorians

What to know

CDC has guidance available on variant influenza viruses for clinicians, laboratorians, and epidemiologists. Links to these guidance documents are included below.

Guidance and recommendations

Interim Guidance for Clinicians on Human Infections with Variant Influenza Viruses

Specimen collection

Interim Guidance on Specimen Collection, Processing, and Testing for Patients with Suspect Influenza A (H3N2)v Virus Infection

Infection prevention and control

Interim Guidance for Infection Control Within Healthcare Settings When Caring for Confirmed Cases, Probable Cases, and Cases Under Investigation for Infection with Novel Influenza A Viruses Associated with Severe Disease
Novel influenza A guidance for infection prevention and control in healthcare settings.
Infection prevention and control measures for patients with confirmed or suspected novel influenza A virus infections, including variant influenza A virus infections, not known to be associated with severe disease and high mortality in infected humans
Prevention Strategies for Seasonal Influenza in Healthcare Settings - CDC

Case definitions

Interim Guidance on Case Definitions for Investigations of Influenza A (H3N2)v Virus Cases

Resources

CDC Expert Commentary on Medscape–CDC's James Kile, DVM, MPH details guidance for swine influenza virus infection in humans in this Medscape Expert Commentary.
MMWR, October 26, 2018: Influenza A(H3N2) Variant Virus Outbreak at Three Fairs — Maryland, 2017
MMWR. Morbidity and Mortality Weekly Report / Vol. 67 / No. 42 / P. 1169–1173
MMWR, September 27, 2012: Influenza A (H3N2) Variant Virus-Related Hospitalizations – Ohio, 2012.
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MMWR, August 17, 2012: Evaluation of Rapid Influenza Diagnostic Tests for Influenza A (H3N2)v Virus and Updated Case Count — United States, 2012.
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Balish A, Garten R, Klimov A, Villanueva J. Analytical detection of influenza A(H3N2)v and other A variant viruses from the USA by rapid influenza diagnostic tests. Influenza Other Respi Viruses. 2012 Sep 18. doi: 10.1111/irv.12017. [Epub ahead of print]
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Content Source:
National Center for Immunization and Respiratory Diseases (NCIRD)