Table 13. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by Age Group and Sex, United States

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The table below is from Sexually Transmitted Infections Surveillance, 2023.

2019-2023

Year Age Group Cases Rates per 100,000 Population*
Total Male Female Unknown Sex Total Male Female
2019 0-4 5 4 1 0 0.0 0.0 0.0
5-9 2 1 1 0 0.0 0.0 0.0
10-14 22 9 13 0 0.1 0.1 0.1
15-19 1,708 1,202 502 4 8.1 11.2 4.9
20-24 6,325 5,064 1,234 27 29.2 45.8 11.7
25-29 8,308 6,924 1,361 23 35.3 57.7 11.8
30-34 6,829 5,725 1,085 19 30.4 50.4 9.8
35-39 4,837 3,987 839 11 22.3 36.6 7.7
40-44 3,276 2,689 579 8 16.4 27.1 5.8
45-54 4,749 4,099 646 4 11.6 20.3 3.1
55-64 2,412 2,210 201 1 5.7 10.8 0.9
65+ 515 485 30 0 1.0 2.0 0.1
Unknown Age 4 3 1 0
TOTAL 38,992 32,402 6,493 97 11.9 20.0 3.9
2020 0-4 1 1 0 0 0.0 0.0 0.0
5-9 2 2 0 0 0.0 0.0 0.0
10-14 24 8 16 0 0.1 0.1 0.2
15-19 1,782 1,166 612 4 8.3 10.6 5.8
20-24 6,351 4,817 1,512 22 29.6 44.0 14.4
25-29 8,659 6,975 1,651 33 37.8 60.0 14.6
30-34 7,779 6,319 1,439 21 34.1 54.7 12.8
35-39 5,284 4,289 983 12 23.8 38.2 8.9
40-44 3,693 2,963 727 3 18.0 28.7 7.1
45-54 4,936 4,227 702 7 12.0 20.5 3.4
55-64 2,544 2,333 208 3 5.9 11.1 0.9
65+ 548 505 40 3 1.0 2.1 0.1
Unknown Age 52 41 11 0
TOTAL 41,655 33,646 7,901 108 12.6 20.5 4.7
2021 0-4 6 4 2 0 0.0 0.0 0.0
5-9 2 0 2 0 0.0 0.0 0.0
10-14 24 4 20 0 0.1 0.0 0.2
15-19 2,122 1,327 790 5 9.8 12.0 7.5
20-24 7,695 5,614 2,057 24 35.8 51.2 19.5
25-29 10,235 7,746 2,456 33 45.7 68.1 22.3
30-34 10,090 7,904 2,156 30 43.7 67.7 18.9
35-39 7,640 5,776 1,841 23 34.3 51.3 16.7
40-44 5,223 3,927 1,279 17 24.7 37.1 12.2
45-54 6,226 5,028 1,183 15 15.3 24.8 5.8
55-64 3,483 3,105 372 6 8.1 14.8 1.7
65+ 835 782 53 0 1.5 3.1 0.2
Unknown Age 186 132 54 0
TOTAL 53,767 41,349 12,265 153 16.2 25.2 7.3
2022 0-4 6 3 2 1 0.0 0.0 0.0
5-9 6 3 3 0 0.0 0.0 0.0
10-14 39 12 27 0 0.2 0.1 0.3
15-19 2,274 1,377 893 4 10.5 12.4 8.5
20-24 8,235 5,811 2,415 9 36.3 50.1 21.7
25-29 10,317 7,693 2,612 12 46.5 67.8 24.1
30-34 11,116 8,346 2,762 8 47.7 70.5 24.1
35-39 8,524 6,297 2,217 10 38.3 55.7 20.2
40-44 6,130 4,474 1,652 4 28.6 41.4 15.6
45-54 7,203 5,710 1,489 4 17.8 28.2 7.4
55-64 4,102 3,614 485 3 9.7 17.5 2.3
65+ 1,058 965 93 0 1.8 3.7 0.3
Unknown Age 6 4 2 0
TOTAL 59,016 44,309 14,652 55 17.7 26.8 8.7
2023 0-4 5 3 2 0 0.0 0.0 0.0
5-9 4 0 4 0 0.0 0.0 0.0
10-14 49 18 31 0 0.2 0.2 0.3
15-19 2,124 1,226 896 2 9.6 10.9 8.3
20-24 7,104 4,948 2,147 9 32.6 44.5 20.1
25-29 9,032 6,557 2,463 12 41.0 58.7 22.7
30-34 9,891 7,373 2,506 12 42.0 62.0 21.5
35-39 7,734 5,629 2,098 7 34.4 49.5 18.8
40-44 5,700 4,148 1,546 6 26.0 37.7 14.2
45-54 6,526 5,011 1,512 3 16.1 24.8 7.4
55-64 3,815 3,326 485 4 9.1 16.2 2.3
65+ 1,021 947 73 1 1.7 3.5 0.2
Unknown Age 2 2 0 0
TOTAL 53,007 39,188 13,763 56 15.8 23.6 8.1
* No population data are available for unknown sex and age; therefore, rates are not calculated.

NOTE: Cases and rates shown in this table include District of Columbia but exclude US territories. See Technical Notes for more information on syphilis case reporting. This report includes data from years that coincide with the COVID-19 pandemic, which introduced uncertainty and difficulty in interpreting case data. See Impact of COVID-19 on STIs for more information.
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Content Source:
National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention; About Division of STD Prevention