References and Resources

Overview

Fact Sheets

• RSV in Infants and Young Children (cdc.gov)
  • Spanish
• Older adults are at high risk for severe RSV disease (cdc.gov)
  • Spanish

RSV Global Surveillance

• Li Y, Wang, X, Blau DM, et al. Global, Regional, and National Disease Burden Estimates of Acute Lower Respiratory Infections Due to Respiratory Syncytial Virus in Children Younger Than 5 Years in 2019: A Systematic Analysis. Lancet. 2022 May–3 June 28 399(10340):2047-2064.
• Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus – associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis. 2020 Oct 7;222(supplement_7):S577-S583.
• Shi T, McAllister DA, O'Brien KL, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet. 2017 Sep 2;390(10098):946-985. Epub 2017 Jul 7.
• Surveillance for Respiratory Syncytial Virus in CDC's Global Disease Detection Network: Epidemiology, Disease Burden and Clinical Characteristics. J Infect Dis. 2013;208(S3):S165-246.

RSV Prophylaxis Guidelines

• American Academy of Pediatrics Committee on Infectious Diseases; American Academy of Pediatrics Bronchiolitis Guidelines Committee. Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. Pediatrics. 2014 Aug;134(2):415-20. Erratum in: Pediatrics. 2014 Dec;134(6):1221.
• Updated Guidance: Use of Palivizumab Prophylaxis to Prevent Hospitalization From Severe Respiratory Syncytial Virus Infection During the 2022-2023 RSV Season (aap.org)

RSV Hospitalizations

• Hall CB, Weinberg GA, Blumkin AK, et al. Respiratory syncytial virus-associated hospitalizations among children less than 24 months of age. Pediatrics. 2013;132(2):e341-348. Epub 2013 Jul 1522.
• Hall CB, Weinberg GA, Iwane MK, et al. The burden of respiratory syncytial virus infection in young children. N Engl J Med. 2009;360(6):588-598.
• Holmen JE, Kim L, Cikesh B, et al. Relationship between neighborhood census-tract level socioeconomic status and respiratory syncytial virus-associated hospitalizations in U.S. adults, 2015–2017. BMC Infectious Diseases. 2021; 21, 293.
• Kujawski SA, Whitaker M, Ritchey MD, et al. Rates of respiratory syncytial virus (RSV)-associated hospitalization among adults with congestive heart failure-United States, 2015-2017. PLoS One. 2022;17(3):e0264890.
• Lively JY, Curns AT, Weinberg GA, et al. Respiratory Syncytial Virus-Associated Outpatient Visits Among Children Younger Than 24 Months. J Pediatr Infect Dis Soc. 2019;8(3):284-
• McLaughlin JM, Khan F, Schmitt H-J, et al. Respiratory Syncytial Virus–Associated Hospitalization Rates among US Infants: A Systematic Review and Meta-Analysis. J Infect Dis. 2022;225(6):1100-1111.
• Rha B, Curns AT, Lively JY, et al. Respiratory Syncytial Virus–Associated Hospitalizations Among Young Children: 2015–2016. Pediatrics. 2020;146(1):e20193611

RSV Mortality

• Blau, DM, et al. CHAMPS Consortium. Deaths Attributed to Respiratory Syncytial Virus in Young Children in High-Mortality Rate Settings: Report from Child Health and Mortality Prevention Surveillance (CHAMPS). Clin infect Dis. 2021, 73(Suppl_3), S218–S228.
• Hansen CL, Chaves SS, Demont C, Viboud C. Mortality Associated With Influenza and Respiratory Syncytial Virus in the US, 1999-2018. JAMA Network Open. 2022 Feb 1;5(2):e220527.
• Thompson WW, Shay DK, Weintraub E, et al. Mortality Associated with Influenza and Respiratory Syncytial Virus in the United States. JAMA. 2003;289(2):179-86.

RSV Seasonality

• Midgley CM, Haynes AK, Baumgardner JL, et al. Determining the Seasonality of Respiratory Syncytial Virus in the United States: The Impact of Increased Molecular Testing. J Infect Dis. 2017;216(3):345-55.
• Mullins JA, LaMonte AC, Bresee JS, Anderson LJ. Substantial Variability in Community Respiratory Syncytial Virus Season Timing. Pediatr Infect Dis J. 2003;22:1-0.
• Olsen SJ, Winn AK, Budd AP, et al. Changes in Influenza and Other Respiratory Virus Activity During the COVID-19 Pandemic — United States, 2020–2021. MMWR Morb Mortal Wkly Rep. 2021; 70:1013–1019.
• Rose EB, Wheatley A, Langley G, et al. Respiratory Syncytial Virus Seasonality – United States, 2014-2017. MMWR Morb Mortal Wkly Rep. 2018;67(2):71-76.

RSV in Older Adults

• Branche AR, Saiman L, Walsh E, et al. Change in Functional Status Associated with Respiratory Syncytial Virus Infection in Hospitalized Older Adults, Influenza Other Respi Viruses. 2022;16:1151-1160.
• Falsey AR, Hennessey RN, Formica MA, et al. Respiratory Syncytial Virus Infection in Elderly and High-Risk Adults. New Engl J Med. 2005;352(17):1749-59.
• Falsey AR & Walsh EE. Respiratory Syncytial Virus Infection in Adults. Clin Microbiol Rev.2000;13(3):371-84.
• McLaughlin JM, Khan F, Begier E, et al. Rates of Medically Attended RSV among US Adults: A Systematic Review and Meta-analysis. Open Forum Infect Dis. 2022; 9(7): ofac300.

RSV in Special Populations

• Bruden DJ, Singleton R, Hawk CS, et al. Eighteen Years of Respiratory Syncytial Virus Surveillance: Changes in Seasonality and Hospitalization Rates in Southwestern Alaska Native Children. Pediatr Infect Dis J. 2015;34(9):945-950.
• Foote EM, Singleton RJ, Holman RC, et al. Lower respiratory tract infection hospitalizations among American Indian/Alaska Native children and the general United States child population. Int J Circumpolar Health. 2015 Nov 5; 74:29256.
• Holman RC, Curns AT, Cheek JE, Bresee JS, et al. Respiratory syncytial virus hospitalizations among American Indian and Alaska Native infants and the general United States infant population. Pediatrics. 2004 Oct;114(4):e437-44.
• Rose EB, Dahl, RM, Havers, FP, et al. Respiratory Syncytial Virus-Associated Hospitalizations in Children with Neurological Disorders, 2006-2015. Pediatr Infect Dis J.2021;10(10), 951–957.
• Singleton RJ, Bulkow LR, Miernyk K, et al. Viral Respiratory Infections in Hospitalized and Community Control Children in Alaska. J Med Virol. 2010; 82(7):1282-90.

RSV - Other

• Rainisch G, Adhikari B, Meltzer MI, Langley G. Estimating the impact of multiple immunization products on medically-attended respiratory syncytial virus (RSV) infections in infants. Vaccine. 2020;38(2):251-7. Epub 2019/11/20.

Podcast

Respiratory Syncytial Virus (RSV)

Dr. Eileen Schneider talks about a common cause of respiratory illness in young children. Running Time: 4:22 minutes