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Time-Varying Effects of Parental Alcoholism on Depression

CME ACTIVITY — Volume 14 — December 14, 2017

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Figure 1.
Age-varying effects of parental alcoholism on lifetime major depressive disorder for respondents aged 18–90 years, National Epidemiologic Survey on Alcohol and Related Conditions, Wave III, 2012–2013. Age-varying effects are presented as odds ratios (ORs) across ages; the solid line represents the OR point estimates, and the surrounding shading represents 95% confidence intervals. The horizontal line represents an OR of 1.00.

Age, y Parental Alcoholism Lower Limit Parental Alcoholism Upper Limit Parental Alcoholism Estimate (Odds Ratio)
18.0 1.195427179 2.272260309 1.648126734
18.7272727 1.260284189 2.275778416 1.69355471
19.4545455 1.323772899 2.280927531 1.737650728
20.1818182 1.385351709 2.287849951 1.780302458
20.9090909 1.444477368 2.296690058 1.821405175
21.6363636 1.500622699 2.307580984 1.860862275
22.3636364 1.553300166 2.320625326 1.898585711
23.0909091 1.60209056 2.335870551 1.934496358
23.8181818 1.646673787 2.353282051 1.968524287
24.5454545 1.686856114 2.37271941 2.000608968
25.2727273 1.722586815 2.393922902 2.030699393
26.0 1.753958399 2.416515995 2.05875412
26.7272727 1.781188888 2.440025357 2.084741244
27.4545455 1.804590073 2.463914416 2.108638304
28.1818182 1.824529489 2.487622715 2.130432116
28.9090909 1.841394202 2.510602989 2.150118552
29.6363636 1.85556197 2.532350392 2.167702259
30.3636364 1.867381868 2.552421807 2.183196327
31.0909091 1.877163724 2.570445928 2.196621918
31.8181818 1.885174314 2.586126186 2.208007849
32.5454545 1.891638012 2.599238875 2.217390145
33.2727273 1.896739946 2.609628446 2.224811569
34.0 1.900630285 2.617201424 2.230321118
34.7272727 1.903428782 2.621919841 2.23397352
35.4545455 1.905229075 2.623794732 2.235828708
36.1818182 1.906102546 2.622879964 2.235951291
36.9090909 1.906101639 2.619266515 2.234410033
37.6363636 1.905262677 2.613077218 2.231277324
38.3636364 1.903608223 2.604461965 2.226628666
39.0909091 1.901149081 2.593593312 2.220542173
39.8181818 1.897886019 2.580662423 2.213098084
40.5454545 1.893811306 2.565875303 2.204378293
41.2727273 1.888910167 2.549449243 2.194465902
42.0 1.883162224 2.531609402 2.183444799
42.7272727 1.876543032 2.512585464 2.17139926
43.4545455 1.869025779 2.492608297 2.158413575
44.1818182 1.8605832 2.471906558 2.144571709
44.9090909 1.851189775 2.45070322 2.129956981
45.6363636 1.840824171 2.429212002 2.114651785
46.3636364 1.829471908 2.40763378 2.098737326
47.0909091 1.817128103 2.386153072 2.082293401
47.8181818 1.803800135 2.364934788 2.065398192
48.5454545 1.789509965 2.344121462 2.048128101
49.2727273 1.774295891 2.323831223 2.030557606
50.0 1.758213466 2.304156723 2.012759145
50.7272727 1.741335442 2.285165178 1.994803027
51.4545455 1.723750686 2.266899561 1.976757363
52.1818182 1.705562128 2.249380853 1.958688029
52.9090909 1.686883971 2.232611154 1.940658643
53.6363636 1.667838406 2.216577355 1.922730569
54.3636364 1.648552156 2.201255072 1.904962938
55.0909091 1.629153115 2.186612553 1.887412687
55.8181818 1.609767297 2.17261433 1.87013462
56.5454545 1.590516228 2.159224489 1.853181478
57.2727273 1.571514848 2.146409484 1.836604033
58.0 1.552869893 2.134140499 1.820451189
58.7272727 1.534678724 2.122395428 1.804770098
59.4545455 1.517028509 2.111160516 1.789606295
60.1818182 1.499995669 2.100431798 1.775003831
60.9090909 1.4836455 2.090216384 1.761005432
61.6363636 1.468031882 2.08053371 1.74765266
62.3636364 1.453197003 2.07141681 1.734986081
63.0909091 1.439171043 2.062913685 1.723045455
63.8181818 1.42597177 2.055088813 1.711869923
64.5454545 1.413604026 2.048024841 1.701498211
65.2727273 1.402059091 2.041824467 1.69196884
66.0 1.391313947 2.03661252 1.683320351
66.7272727 1.381330494 2.032538193 1.675591533
67.4545455 1.372054796 2.029777369 1.668821672
68.1818182 1.363416488 2.028534933 1.663050803
68.9090909 1.355328512 2.029046931 1.658319981
69.6363636 1.347687402 2.031582382 1.654671563
70.3636364 1.340374316 2.036444577 1.652149511
71.0909091 1.333257058 2.043971681 1.650799706
71.8181818 1.326193189 2.054536565 1.650670288
72.5454545 1.319034267 2.068545902 1.651812013
73.2727273 1.311631011 2.086438791 1.654278641
74.0 1.303839047 2.10868534 1.658127342
74.7272727 1.295524668 2.135785855 1.663419147
75.4545455 1.286570012 2.168271365 1.670219421
76.1818182 1.276877083 2.206706168 1.678598384
76.9090909 1.266370228 2.25169296 1.688631673
77.6363636 1.254996934 2.303880859 1.700400957
78.3636364 1.242727071 2.363976434 1.713994606
79.0909091 1.229550899 2.432757678 1.729508424
79.8181818 1.21547627 2.511090838 1.747046458
80.5454545 1.200525457 2.599950042 1.766721884
81.2727273 1.184731956 2.700439852 1.788657985
82.0 1.168137532 2.813821052 1.812989238
82.7272727 1.150789662 2.941540212 1.839862513
83.4545455 1.132739419 3.085263815 1.869438403
84.1818182 1.11403981 3.246917982 1.901892713
84.9090909 1.094744514 3.42873509 1.937418109
85.6363636 1.07490697 3.633308915 1.976225968
86.3636364 1.054579739 3.86366024 2.01854844
87.0909091 1.03381408 4.123315369 2.064640764
87.8181818 1.012659698 4.416400501 2.114783865
88.5454545 0.991164591 4.747755626 2.16928727
89.2727273 0.969375 5.123072466 2.228492399
90.0 0.947335398 5.549062135 2.292776262

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Figure 2.
Age-varying effects of parental alcoholism on lifetime persistent depressive disorder for respondents aged 18–90 years, National Epidemiologic Survey on Alcohol and Related Conditions, Wave III, 2012–2013. Age-varying effects are presented as odds ratios (ORs) across ages; the solid line represents the OR point estimates, and the surrounding shading represents 95% confidence intervals. The horizontal line represents an OR of 1.00.

Age Parental Alcoholism Lower Limit Parental Alcoholism Upper Limit Parental Alcoholism Estimate (Odds Ratio)
18.0 2.121333968 6.551176806 3.727899394
18.7272727 2.075574017 5.860781704 3.487762352
19.4545455 2.029848789 5.283819956 3.274958861
20.1818182 1.984035647 4.800238575 3.086072657
20.9090909 1.938049696 4.39400751 2.91818521
21.6363636 1.891863229 4.052213687 2.768796503
22.3636364 1.84552654 3.764360941 2.635759478
23.0909091 1.799186017 3.521828612 2.517225614
23.8181818 1.753093756 3.317455994 2.411599342
24.5454545 1.707603271 3.145230146 2.317499792
25.2727273 1.663149306 3.000060743 2.233729828
26.0 1.620212854 2.877621024 2.159249539
26.7272727 1.579278657 2.774236703 2.093153796
27.4545455 1.540794475 2.686804367 2.034653121
28.1818182 1.505138875 2.612721855 1.98305553
28.9090909 1.4726045 2.549829007 1.937753769
29.6363636 1.443395174 2.496351313 1.898215329
30.3636364 1.417631989 2.450842872 1.86397244
31.0909091 1.395365259 2.412132959 1.834613456
31.8181818 1.376588712 2.379277958 1.80977545
32.5454545 1.361253018 2.351518978 1.789137308
33.2727273 1.349275107 2.328241584 1.77241034
34.0 1.34054929 2.308950615 1.759335701
34.7272727 1.334956119 2.293250066 1.749682316
35.4545455 1.332367535 2.280824388 1.74324306
36.1818182 1.332650157 2.271423676 1.739831348
36.9090909 1.335667115 2.264852012 1.739278112
37.6363636 1.341277836 2.260956984 1.741428003
38.3636364 1.349333336 2.259616451 1.746131668
39.0909091 1.359678241 2.260738268 1.753247453
39.8181818 1.372151379 2.264258285 1.76264152
40.5454545 1.386584443 2.270136172 1.77418587
41.2727273 1.402800706 2.278351648 1.787756499
42.0 1.420613986 2.288900855 1.803231701
42.7272727 1.439825989 2.301790321 1.820488266
43.4545455 1.46021974 2.3170262 1.839393214
44.1818182 1.481565837 2.334616571 1.859808634
44.9090909 1.503626278 2.354567875 1.881592446
45.6363636 1.52615736 2.376878206 1.904597114
46.3636364 1.548913488 2.401529913 1.928668471
47.0909091 1.571651669 2.428481794 1.953644662
47.8181818 1.594132997 2.457658161 1.979351907
48.5454545 1.616121257 2.488935549 2.005597579
49.2727273 1.637394377 2.522142752 2.032176755
50.0 1.657749164 2.557057044 2.058873278
50.7272727 1.677002996 2.593401109 2.085459525
51.4545455 1.694993838 2.630842419 2.111696401
52.1818182 1.711578621 2.668995055 2.13733359
52.9090909 1.726627828 2.707421364 2.162107553
53.6363636 1.740019732 2.745634607 2.185739782
54.3636364 1.751641031 2.783109656 2.20794227
55.0909091 1.761383135 2.819292424 2.228419648
55.8181818 1.769137897 2.853610183 2.246871139
56.5454545 1.774793588 2.885483038 2.262992884
57.2727273 1.778231237 2.914336455 2.276480643
58.0 1.779321666 2.939615161 2.28703322
58.7272727 1.777923295 2.960796734 2.294356007
59.4545455 1.773879747 2.977405156 2.298164203
60.1818182 1.767017848 2.989025971 2.298186729
60.9090909 1.757146192 2.995321497 2.294170386
61.6363636 1.74405449 2.996045392 2.285884165
62.3636364 1.727514047 2.99105584 2.273123617
63.0909091 1.70727983 2.980326367 2.255715207
63.8181818 1.683095655 2.963954754 2.233521741
64.5454545 1.65470297 2.942168241 2.206448396
65.2727273 1.621849546 2.915316254 2.174443456
66.0 1.584304069 2.883859212 2.13750085
66.7272727 1.541875679 2.848350404 2.095662715
67.4545455 1.494437512 2.809410365 2.049021287
68.1818182 1.441952684 2.767695097 1.997720044
68.9090909 1.384500016 2.723860792 1.941953993
69.6363636 1.322295886 2.678528746 1.881969059
70.3636364 1.255708302 2.632254659 1.818060513
71.0909091 1.18525999 2.585505937 1.750570405
71.8181818 1.111619045 2.538649444 1.679884243
72.5454545 1.035577447 2.491949854 1.606426801
73.2727273 0.958018876 2.445576339 1.530656165
74.0 0.879880702 2.399616068 1.453057422
74.7272727 0.802113889 2.35409105 1.374135775
75.4545455 0.725644318 2.308975503 1.294409113
76.1818182 0.651338299 2.264211802 1.214400208
76.9090909 0.579974061 2.219723938 1.134628709
77.6363636 0.512220104 2.175428095 1.055603148
78.3636364 0.448620673 2.13124046 0.977813137
79.0909091 0.389588073 2.087082647 0.901721968
79.8181818 0.335401273 2.042885183 0.827759803
80.5454545 0.286210024 1.99858954 0.756317632
81.2727273 0.242043585 1.954149091 0.687742141
82.0 0.202823099 1.909529338 0.62233163
82.7272727 0.168376606 1.864707633 0.560333063
83.4545455 0.138455714 1.819672597 0.501940305
84.1818182 0.112752985 1.774423347 0.44729356
84.9090909 0.090919169 1.728968626 0.396479999
85.6363636 0.07257957 1.683325891 0.349535504
86.3636364 0.057348922 1.637520403 0.306447434
87.0909091 0.044844346 1.591584332 0.267158301
87.8181818 0.034696095 1.545555889 0.231570192
88.5454545 0.026555975 1.499478512 0.199549778
89.2727273 0.020103438 1.453400077 0.170933726
90.0 0.015049499 1.407372163 0.145534345

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