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Ronnel
May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
CAS number: 299–84–3
NIOSH REL: 10 mg/m3 TWA
Current OSHA PEL: 15 mg/m3 TWA
1989 OSHA PEL: 10 mg/m3 TWA
1993-1994 ACGIH TLV: 10 mg/m3 TWA
Description of substance: White to light-tan, crystalline solid.
LEL:. . Noncombustible Solid
Original (SCP) IDLH: 5,000 mg/m3
Basis for original (SCP) IDLH: No useful data on acute inhalation toxicity are available on which to base the IDLH for ronnel. The chosen IDLH, therefore, has been estimated from the statement by ACGIH [1971] that the dog oral LD50 is greater than 500 mg/kg.
Short-term exposure guidelines: None developed
ACUTE TOXICITY DATA:
Lethal dose data:
| Species | Reference | Route | LD50(mg/kg) | LDLo(mg/kg) | Adjusted LD | Derived value |
|---|---|---|---|---|---|---|
| MouseRabbit
G. pig Dog Rat |
AAPCO 1966AAPCO 1966
AAPCO 1966 Klimmer 1971 Gig Sanit 1990 |
oraloral
oral oral oral |
2,000420
1,400 500 625 |
———-
—– —– —– |
7,000 mg/m32,940 mg/m3
9,800 mg/m3 3,500 mg/m3 4,375 mg/m3 |
700 mg/m3294 mg/m3
980 mg/m3 350 mg/m3 438 mg/m3 |
Human data: None relevant for use in determining the revised IDLH.
| Revised IDLH: 300 mg/m3Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ronnel. Therefore, the revised IDLH for ronnel is 300 mg/m3 based on acute oral toxicity in animals [AAPCO 1966; Klimmer 1971]. This may be a conservative value due to the lack of relevant acute toxicity data for workers. |
REFERENCES:
1. AAPCO [1966]. Pesticide chemicals official compendium. Topeka, KS: Association of American Pesticide Control Officials, Inc., p. 965.
2. ACGIH [1971]. Ronnel. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 222.
3. Klimmer OR [1971]. Pflanzenschutz-und schaedlingsbekaempfungsmittel: Abriss einer Toxikologie und Therapie von Vergiftungen. 2nd ed. Hattingen, Germany: Hundt-Verlag, p. 26.
4. Gig Sanit [1990]. Long-term effects from transformation products of pesticides and surfactants; 45(6):14-17 (in Russian).