Preventing Bladder Cancer from Exposure to o-Toluidine and Aniline

WARNING! Workers exposed to o-toluidine or aniline may be at increased risk for developing bladder cancer.

The National Institute for Occupational Safety and Health (NIOSH) requests assistance in preventing bladder cancer in workers exposed to o-toluidine and aniline, both of which have been shown to induce tumors in experimental animals. This Alert presents significant new epidemiologic evidence that clearly associates o-toluidine and aniline with an increased risk of bladder cancer.

NIOSH requests employers, editors of appropriate trade journals, and all those responsible for occupational safety and health to bring this information to the attention of workers potentially exposed to o-toluidine and aniline. NIOSH further requests that employers and workers implement the recommendations in this Alert to reduce exposures to the lowest feasible concentration.

Preventing Bladder Cancer from Exposure to o-Toluidine and Aniline [PDF – 447 KB]