NIOSH logo and tagline

Platinum

Related Pages
RTECS #
TP2160000
CAS #
7440-06-4
See: NMAM or OSHA Methods
Updated
March 2016
Molecular Weight
195.09
Molecular Formula
Pt
Synonyms
C.I. 77795
Liquid bright platinum
Platin (German)
Platinum (ACGIH)
Platinum Black
Platinum sponge

Tumorigenic Data and References

Route/OrganismDoseEffectReference
implant/mouse lowest published toxic dose: 23 gm/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application		NATWAY 42,75,1955
implant/rat lowest published toxic dose: 5250 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application		NATWAY 42,75,1955

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 17 mg/kgLiver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects

Biochemical: Metabolism (intermediary): Lipids including transport		EKFAE9 57,38,1994

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 9100 mg/kg/26W- intermittentBlood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Metabolism (intermediary): Other proteins		GTPZAB 23(9),4,1979

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 1 mg/m3DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWJJATDK 26,191,2006
TOXICOLOGY REVIEWENTOX* -,448,2005
TOXICOLOGY REVIEWHBTME* ,769,2007
TOXICOLOGY REVIEWNTAPM* -,629,1995
TOXICOLOGY REVIEWMUREAV 762,76,2014
TOXICOLOGY REVIEWTOLED5 207,42,2011

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.002 mg/m3DTLVS* 3,213,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 1 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 1 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.002 mg(Pt)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 1 mg/m3 (dust), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 1 mg/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 1 mg/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 1 mg/m3, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 1 mg/m3 (dust), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.002 mg/m3, 2006
Occupational Exposure Limit-KOREAtime-weighted average 1 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.002 mg(Pt)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 1 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.002 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 1 mg/m3, JUL2005
Occupational Exposure Limit-SWEDENtime-weighted average 1 mg/m3 (total dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 1 mg/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 1 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 5 mg/m3, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PLATINUM (as Pt), metal-air10H time-weighted average 1 mg/m3NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PLATINUM (as Pt), soluble salts-air10H time-weighted average 0.002 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code X4385; Number of Industries 1; Total Number of Facilities 7; Number of Occupations 1; Total Number of Employees Exposed 28; Total Number of Female Employees Exposed 7
National Occupational Exposure Survey 1983Hazard Code X5987; Number of Industries 1; Total Number of Facilities 23; Number of Occupations 1; Total Number of Employees Exposed 23
National Occupational Exposure Survey 1983Hazard Code X7504; Number of Industries 2; Total Number of Facilities 10; Number of Occupations 1; Total Number of Employees Exposed 428; Total Number of Female Employees Exposed 407
National Occupational Exposure Survey 1983Hazard Code 60125; Number of Industries 16; Total Number of Facilities 677; Number of Occupations 26; Total Number of Employees Exposed 22935; Total Number of Female Employees Exposed 3498
National Occupational Hazard Survey 1974Hazard Code 60125; Number of Industries 3; Total Number of Facilities 63; Number of Occupations 4; Total Number of Employees Exposed 680

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Elements by ICP, 7300
NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
NIOSH Analytical Method, 1994: Metals in urine, 8310
OSHA ANALYTICAL METHOD #ID121
Page last reviewed: November 16, 2018
Content source: National Institute for Occupational Safety and Health