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Zinc chloride

RTECS #
ZH1400000
CAS #
7646-85-7
See: NMAM or OSHA Methods
Updated
June 2018
Molecular Weight
136.27
Molecular Formula
Cl2Zn
Synonyms
Butter of zinc
Chlorure de zinc (French)
Zinc (chlorure de) (French)
Zinc butter
Zinc chloride fume
Zinc chloride fume (ACGIH:OSHA)
Zinc dichloride
Zinco (cloruro di) (Italian)
Zinkchlorid (German)
Zinkchloride (Dutch)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
skin /rabbit 1%/5D open irritation test severeHBTME* ,925,2007

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysislymphocyte/human300 µmol/LTXCYAC 10,67,1978
Cytogenetic AnalysisAscites tumor/rat700 mg/kgGANNA2 54,155,1963
Cytogenetic Analysisoral/mouse18 gm/kg/30D-continuousCRSBAW 176,563,1982
Cytogenetic Analysisintraperitoneal/mouse7.5 mg/kgHBTME* -,925,2007
DNA Damagefibroblast/human2 mmol/LMUREAV 193,237,1988
DNA inhibitionparenteral/mouse16 mg/kgCCCCAK 48,3020,1983
DNA inhibitionlymphocyte/human360 µmol/LIAAAAM 77,461,1985
host-mediated assaySalmonella typhimurium/mouse6 mg/kgSOGEBZ 13,1010,1977
micronucleus testlymphocyte/human100 mg/LTXAPA9 197,259,2004
micronucleus testother cell types/non-mammalian species170 µg/L/48HMUREAV 209,131,1988
morphological transformembryo/hamster100 nmol/L/7DARTODN 79,90,2005
morphological transformfibroblast/mouse10 mg/L/10DMUREAV 702,100,2010
morphological transformembryo/hamster180 µmol/LCNREA8 39,193,1979
mutation in microorganisms/Salmonella typhimurium25 mg/LTXAPA9 197,259,2004
mutation in microorganisms/Salmonella typhimurium90 mmol/L (-enzymatic activation step)SOGEBZ 13,1010,1977
other mutation test systemslymphocyte/human2 mgCRSBAW 176,563,1982
phage inhibition capacity/Escherichia coli3200 µmol/LENMUDM 6,59,1984
specific locus testoral/Drosophila melanogaster6 mmol/LMUREAV 320,133,1994
Unscheduled DNA Synthesislymphocyte/human180 µmol/LIAAAAM 77,461,1985

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse 20500 µg/kg (8D pregnant)Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
JPMSAE 66,1755,1977
intraperitoneal/mouse 12500 µg/kg (11D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemDABBBA 36,6103,1975
intraperitoneal/rat 30 gm/kg (7-8D pregnant)Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Effects on embryo or fetus: Fetal death
TJADAB 29(3),23A,1984
intraperitoneal/mouse 50 mg(Zn)/kg (8-11D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
HBTME* -,925,2007
intravaginal/rabbit 29184 µg/kg (1D prior to copulation)Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)CCPTAY 22,659,1980
oral/rat 1.8 gm/kg (98D male/98D pre-3W after birth)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)

Reproductive: Specific developmental abnormalities: Eye, ear
TOXID9 72,75,2003
oral/rat 7.1 gm/kg (98D male/98D pre-3W after birth)Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)TOXID9 72,75,2003
oral/mouse 186 mg/kg (98D male/98D pre-3W after birth)Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)

Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow)

Reproductive: Specific developmental abnormalities: Urogenital system
TOXID9 72,75,2003
oral/mouse 186 mg/kg (multigenerations)Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)TOXID9 72,75,2003
oral/rat 1.8 gm/kg (98D male/98D pre-3W after birth)Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)
TOXID9 72,76,2003
oral/mouse 456 mg/kg (70D male/70D pre-21D after birth)Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)

Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females)

Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)
TOXID9 1,110,2001
oral/mouse 456 mg/kg (70D male/70D pre-21D after birth)Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
TOXID9 1,110,2001
oral/rat 155 mg/kg (33D male)Reproductive: Other effects on male

Endocrine: Change in LH

Endocrine: Change in gonadotropins
JOENAK 79,151,1978
oral/rat 6 gm/kg (77D male/77D pre-21D after birth)Reproductive: Effects on newborn: Behavioral

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
TOXID9 54,369,2000
parenteral/rat 37500 µg/kg (10D pregnant)Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)56ZJAL 5,722,1998

Tumorigenic Data and References

Route/OrganismDoseEffectReference
parenteral/chicken lowest published toxic dose: 15 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Reproductive: Tumorigenic effects: Testicular tumors
CANCAR 6,464,1953
parenteral/hamster lowest published toxic dose: 17 mg/kgTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Gastrointestinal: Colon tumors
CNREA8 34,2612,1974

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/embryo Inhibitor Concentration Low: 184 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.

In Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.
TIVIEQ 40,256,2017
In Vitro/embryo Inhibitor Concentration Low: 369 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.TIVIEQ 40,256,2017
In Vitro/gtdInhibitor Concentration Low: 1 mg/L/72HIn Vitro Toxicity Studies: Other assaysTIVIEQ 29,1124,2015
In Vitro/Human, colon tumor Inhibitor Concentration Low: 20 mg/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 35,169,2016
In Vitro/Human, fibroblast Inhibitor Concentration Low: 10 mg/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TOLED5 207,197,2011
In Vitro/Human, leukemia cells Inhibitor Concentration Low: 100 µmol/L/1HImmunological Including Allergic: Decrease in cellular immune responseTXAPA9 254,245,2011
In Vitro/Human, liver tumor Inhibitor Concentration (50 percent kill): 0.329 mmol/L/24HIn Vitro Toxicity Studies: Cell protein synthesisTIVIEQ 3,189,1989
In Vitro/Human, liver tumor Inhibitor Concentration (10 percent kill): 75.7 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TOLED5 205,146,2011
In Vitro/Human, liver tumor Inhibitor Concentration (20 percent kill): >100 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TOLED5 205,146,2011
In Vitro/Human, lung Inhibitor Concentration (50 percent kill): 120 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.TIVIEQ 36,53,2016
In Vitro/Human, lung Inhibitor Concentration Low: 80 µmol/L/20HBiochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammationTIVIEQ 36,53,2016
In Vitro/kvxInhibitor Concentration Low: 200 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.TXCYAC 270,66,2010
In Vitro/kvxInhibitor Concentration Low: 500 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.

In Vitro Toxicity Studies: Other assays
TXCYAC 270,66,2010
In Vitro/Mouse, macrophage Inhibitor Concentration Low: 5 mg/L/24HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.TOLED5 199,389,2010
In Vitro/Mouse, macrophage Inhibitor Concentration (50 percent kill): 13.33 mg/L/24HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.TOLED5 199,389,2010
In Vitro/Mouse, macrophage Inhibitor Concentration Low: 5 mg/L/24HIn Vitro Toxicity Studies: Cell membrane integrity: Cytoplasmic enzymes leakage (lactate dehydrogenase, ATP enzymes etc.)TOLED5 199,389,2010
In Vitro/Mouse, macrophage Inhibitor Concentration Low: 5 mg/L/24HIn Vitro Toxicity Studies: Other assaysTOLED5 199,389,2010
In Vitro/Non-mammalian species, fibroblast Inhibitor Concentration Low: 200 µmol/L/66HIn Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.TXCYAC 270,66,2010
In Vitro/Non-mammalian species, fibroblast Inhibitor Concentration (50 percent kill): 0.12 mmol/L/24HIn Vitro Toxicity Studies: Cell countingTIVIEQ 7,537,1993
In Vitro/paaInhibitor Concentration Low: 50 µmol/L/8HIn Vitro Toxicity Studies: Cell membrane integrity: Cytoplasmic enzymes leakage (lactate dehydrogenase, ATP enzymes etc.)TOLED5 199,102,2010
In Vitro/paaInhibitor Concentration Low: 10 µmol/L/24HIn Vitro Toxicity Studies: Cell membrane integrity: Cytoplasmic enzymes leakage (lactate dehydrogenase, ATP enzymes etc.)TOLED5 199,102,2010
In Vitro/pzxInhibitor Concentration Low: 30 µmol/L/2HIn Vitro Toxicity Studies: Other assaysTXCYAC 276,27,2010
In Vitro/pzxInhibitor Concentration Low: 10 µmol/L/24HIn Vitro Toxicity Studies: Cell membrane integrity: Cytoplasmic enzymes leakage (lactate dehydrogenase, ATP enzymes etc.)TOLED5 204,108,2011
In Vitro/pzxInhibitor Concentration Low: 50 µmol/L/4HIn Vitro Toxicity Studies: Cell membrane integrity: Cytoplasmic enzymes leakage (lactate dehydrogenase, ATP enzymes etc.)TOLED5 204,108,2011
In Vitro/pzxInhibitor Concentration Low: 50 µmol/L/4HIn Vitro Toxicity Studies: Other assaysTOLED5 204,108,2011
In Vitro/pzxInhibitor Concentration Low: 50 µmol/L/4HIn Vitro Toxicity Studies: Apoptosis in vitroTOLED5 204,108,2011
In Vitro/pzxInhibitor Concentration Low: 50 µmol/L/1HIn Vitro Toxicity Studies: Other assaysTOLED5 204,108,2011
inhalation/man lowest published toxic concentration: 4800 mg/m3/30MLung, Thorax, or Respiration: Other changesFerJJ# 10JAN1974
inhalation/rat Lowest published lethal concentration: 1960 mg/m3/10MEye: Other eye effects

Behavioral: Excitement
ARTODN 59,160,1986
inhalation/rat lethal concentration (50 percent kill): 2000 mg/m3HBTME* -,925,2007
intraperitoneal/guinea pig lowest published lethal dose: 173 mg/kgAEHLAU 11,201,1965
intraperitoneal/mouse lethal dose (50 percent kill): 24 mg/kgTXAPA9 63,461,1982
intraperitoneal/rat lethal dose (50 percent kill): 58 mg/kgEye: Miosis (pupilliary constriction)

Vascular: BP elevation not characterized in autonomic section

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VHTODE 30,224,1988
intraperitoneal/rat lowest published toxic dose: 9.3 mg/kgEndocrine: Hyperglycemia

Blood: Other changes
TXAPA9 32,316,1975
intraperitoneal/rat lowest published toxic dose: 5 mg/kgEye: Retinal changes pigmentary deposition, retinitis, other)

Liver: Other changes

Biochemical: Metabolism (intermediary): Other proteins
TXAPA9 201,149,2004
intratracheal/rat Lethal dose: >1500 µL/kgLung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
ARDSBL 141(Suppl),A3-A937,1990
intravenous/mouse lethal dose (50 percent kill): 9090 µg/kgINJPD2 23,153,1991
intravenous/rabbit lowest published lethal dose: 11 mg/kgTXAPA9 9,269,1966
intravenous/rat lethal dose (50 percent kill): 3690 µg/kgINJPD2 23,153,1991
oral/child lowest published toxic dose: 169 mg/kgLung, Thorax, or Respiration: Dyspnea

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Skin: After systemic exposure: Dermatitis, other
AEMED3 23,1383,1994
oral/guinea pig lethal dose (50 percent kill): 200 mg/kgFOREAE 7,313,1942
oral/mouse lowest published toxic dose: 2.04 mg/kgNutritional and Gross Metabolic: Changes in: Other metalsFCTOD7 39,571,2001
oral/mouse lowest published toxic dose: 1.56 mg/kgBlood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)TOXID9 66,34,2002
oral/mouse lethal dose (50 percent kill): 329 mg/kgINJPD2 23,153,1991
oral/rat lethal dose (50 percent kill): 350 mg/kgFOREAE 7,313,1942
subcutaneous/mouse lethal dose (50 percent kill): 330 mg/kgOYYAA2 8,1067,1974

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat lowest published toxic dose: 15 mg/kg/3D- intermittentBehavioral: Alteration of classical conditioning

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases
TOSCF2 97,140,2007
oral/mammal (species unspecified) lowest published toxic dose: 6875 mg/kg/39W- intermittentCardiac: EKG changes not diagnostic of above

Vascular: BP elevation not characterized in autonomic section

Blood: Changes in erythrocyte (RBC) count
GISAAA 51(4),89,1986
oral/mouse lowest published toxic dose: 21504 mg/kg/12W- continuousReproductive: Paternal effects: Testes, epididymis, sperm duct

Related to Chronic Data: Changes in testicular weight
EOGRAL 95,92,2001
oral/mouse lowest published toxic dose: 13440 mg/kg/12W- intermittentBehavioral: Fluid intake

Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
BPBLEO 23,305,2000
oral/mouse lowest published toxic dose: 76.44 mg/kg/14W- intermittentBlood: Normocytic anemia

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TOXID9 72,75,2003
oral/mouse lowest published toxic dose: 109.2 mg/kg/20W- intermittentBehavioral: Euphoria

Blood: Normocytic anemia

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TOXID9 72,75,2003
oral/mouse lowest published toxic dose: 218.4 mg/kg/20W- intermittentBehavioral: Change in psychophysiological tests

Reproductive: Maternal effects: Breasts, lactation (prior to or during pregnancy)
TOXID9 72,75,2003
oral/mouse lowest published toxic dose: 49.42 gm/kg/3W- intermittentCardiac: Other changes

Nutritional and Gross Metabolic: Changes in: Na

Nutritional and Gross Metabolic: Changes in: Ca
CBCPAI 132,53,2002
oral/rat lowest published toxic dose: 284.4 mg/kg/13W- intermittentLiver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in kidney weight

Endocrine: Changes in spleen weight
TOXID9 1,109,2001
oral/rat lowest published toxic dose: 284.4 mg/kg/13W- intermittentEndocrine: Changes in thymus weightTOXID9 1,109,2001
oral/rat lowest published toxic dose: 5690 mg/kg/13W- intermittentBrain and Coverings: Changes in brain weight

Related to Chronic Data: Changes in testicular weight
TOXID9 54,37,2000
oral/rat lowest published toxic dose: 910 mg/kg/26W- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymesGISAAA 44(10),17,1979
oral/rat lowest published toxic dose: 1680 mg/kg/14D- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldTOXID9 48,334,1999
oral/rat lowest published toxic dose: 595 mg/kg/2W- continuousBehavioral: Fluid intakeFCTOD7 39,729,2001
oral/rat lowest published toxic dose: 3360 mg/kg/12W- continuousBehavioral: Fluid intakeFCTOD7 39,729,2001
oral/rat lowest published toxic dose: 900 mg/kg/30D- continuousBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effectsTOLED5 187,137,2009
oral/rat lowest published toxic dose: 1.68 mg/kg/4W- continuousNutritional and Gross Metabolic: Weight loss or decreased weight gainBJPCBM 158,442,2009
oral/rat lowest published toxic dose: 1.26 mg/kg/3W- continuousBehavioral: Food intake (animal)

Behavioral: Fluid intake
BJPCBM 158,442,2009
oral/rat lowest published toxic dose: 345.8 mg/kg/26W- continuousMusculoskeletal: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases
TXCYAC 237,89,2007
subcutaneous/mouse lowest published toxic dose: 40881 µg/kg/3D- intermittentLiver: Other changes

Biochemical: Metabolism (intermediary): Other proteins

Biochemical: Metabolism (intermediary): Other
TXAPA9 242,182,2010
subcutaneous/mouse lowest published toxic dose: 40.5 mg/kg/3D- intermittentLiver: Other changesTOXID9 -,235,2009
subcutaneous/rat lowest published toxic dose: 40 mg/kg/2D- intermittentCardiac: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects

Biochemical: Metabolism (intermediary): Other proteins
TXCYAC 179,85,2002
unreported route/mouse lowest published toxic dose: 437.5 mg/kg/70D- intermittentLiver: Other changes

Reproductive: Paternal effects: Testes, epididymis, sperm duct

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
TOXID9 1,110,2001
unreported route/mouse lowest published toxic dose: 109.2 mg/kg/70D- intermittentReproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct
TOXID9 1,110,2001

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 1 mg/m3;short term exposure limit 2 mg/m3 (fume)DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWANAEA3 35,165,1975
TOXICOLOGY REVIEWFOREAE 7,313,1942
TOXICOLOGY REVIEWFCTXAV 9,105,1971
TOXICOLOGY REVIEWPEXTAR 12,102,1969
TOXICOLOGY REVIEWENTOX* -,479,2005
TOXICOLOGY REVIEWHBTME* ,925,2007
TOXICOLOGY REVIEWHUTOX* -,515,1996
TOXICOLOGY REVIEWMUTAEX 26,205,2011
TOXICOLOGY REVIEWMUREAV 773,134,2017

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESRED CompletedRBREV* -,346,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 1 mg/m3 (fume)DTLVS* 3,283,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-ARAB Republic of Egypttime-weighted average 1 mg/m3 (fume), JAN1993
Occupational Exposure Limit-AUSTRALIAtime-weighted average 1 mg/m3, short term exposure limit 2 mg/m3 (fume), JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 1 mg/m3, short term exposure limit 2 mg/m3 (fume), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg(Zn)/m3 (fume), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 1 mg/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 1 mg/m3 (fume), FEB2006
Occupational Exposure Limit-GERMANYMAK 0.1 mg(Zn)/m3, resp, 2011
Occupational Exposure Limit-GERMANYMAK 2 mg(Zn)/m3, inhal, 2011
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 mg(Zn)/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 1 mg/m3, short term exposure limit 2 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 1 mg/m3;short term exposure limit 2 mg/m3 (fume), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 1 mg/m3, short term exposure limit 2 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 1 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 1 mg/m3; short term exposure limit 2 mg/m3, JUL2005
Occupational Exposure Limit-POLANDtime-weighted average 1 mg/m3, short term exposure limit 2 mg/m3, JAN1999
Occupational Exposure Limit-SWEDENtime-weighted average 1 mg/m3 (resp. dust), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.1 mg(Zn)/m3, KZG-week 0.4 mg(Zn)/m3, resp, JAN2011
Occupational Exposure Limit-SWITZERLANDMAK-week 1 mg/m3, smoke, resp, JAN2011
Occupational Exposure Limit-SWITZERLANDMAK-week 2 mg(Zn)/m3, KZG-week 4 mg(Zn)/m3, inhal, JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 1 mg/m3 (fume), JAN1993
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 1 mg/m3, 2003
Occupational Exposure Limit-TURKEYtime-weighted average 1 mg/m3 (fume), JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 1 mg/m3;short term exposure limit 2 mg/m3 (fume), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 1 mg/m3, fumeCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 1 mg/m3, fumeCFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 1 mg/m3, fumeCFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 1 mg/m3, fumeCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ZINC CHLORIDE FUME-air10H time-weighted average 1 mg/m3;short term exposure limit 2 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 77150; Number of Industries 172; Total Number of Facilities 22612; Number of Occupations 115; Total Number of Employees Exposed 353004; Total Number of Female Employees Exposed 87750
National Occupational Hazard Survey 1974Hazard Code 77150; Number of Industries 192; Total Number of Facilities 20416; Number of Occupations 84; Total Number of Employees Exposed 185570

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: B subtilis rec assay; Sperm morphology-mouse
EPA GENETOX PROGRAM 1988, Negative: In vitro cytogenetics-human lymphocyte
EPA GENETOX PROGRAM 1988, Positive: Cell transform.-SA7/SHE; Host-mediated assay
EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
OSHA ANALYTICAL METHOD #ID-125G
Page last reviewed: November 16, 2018