o-Terphenyl
RTECS #
WZ6472000
CAS #
Updated
April 2012
Molecular Weight
230.32
Molecular Formula
C18H14
Synonyms
1,1':2',1''-Terphenyl (9CI)
1,2-Diphenylbenzene
1,2-Diphenylbenzene
Acute Toxicity Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/rat | lethal dose (50 percent kill): 1900 mg/kg | Gastrointestinal: Hypermotility, diarrhea Skin and Appendages: Other: Hair | AIHAAP 23,372,1962 |
| oral/rat | lethal dose (50 percent kill): 2000 mg/kg | Liver: Changes in liver weight | VCVGH* -,214,1990 |
| oral/rat | lethal dose (50 percent kill): 1900 mg/kg | Behavioral: Rigidity (includes catalepsy) Gastrointestinal: Hypermotility, diarrhea | HPV353 -,-,2003 |
Other Multiple Dose Data and References
| Route/Organism | Dose | Effect | Reference |
|---|---|---|---|
| oral/rat | lowest published toxic dose: 15 gm/kg/30D- continuous | Nutritional and Gross Metabolic: Weight loss or decreased weight gain | AIHAAP 23,372,1962 |
| oral/rat | lowest published toxic dose: 7500 mg/kg/30D- continuous | Liver: Changes in liver weight Kidney, Ureter, and Bladder: Changes in kidney weight Nutritional and Gross Metabolic: Weight loss or decreased weight gain | HPV353 -,,2003 |
| oral/rat | lowest published toxic dose: 1680 mg/kg/14D- continuous | Kidney, Ureter, and Bladder: Changes in kidney weight Endocrine: Changes in adrenal weight Nutritional and Gross Metabolic: Weight loss or decreased weight gain | HPV353 -,,2003 |
Standards and Regulations
| Organization | Standard | Reference |
|---|---|---|
| Mine Safety and Health Administration (MSHA) STANDARD-air | ceiling concentration 1 ppm (9 mg/m3) | DTLWS* 3,28,1973 |
| Occupational Exposure Limit-DENMARK | time-weighted average 0.5 ppm (5 mg/m3), MAY2011 | |
| Occupational Exposure Limit-ICELAND | time-weighted average 0.5 ppm (5 mg/m3), NOV2011 | |
| Occupational Exposure Limit-MEXICO | peak 0.5 ppm, 2004 | |
| Occupational Exposure Limit-UNITED KINGDOM | short term exposure limit 0.5 ppm (4.8 mg/m3), OCT2007 |
Status in Federal Agencies
| Organization | Reference |
|---|---|
| EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
| EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 | |
| NIOSH Analytical Method, 1994: o-Terphenyl, 5021 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health