Stoddard solvent

RTECS #

WJ8925000

CAS #

8052-41-3
See: NMAM or OSHA Methods

Updated

September 2013

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

Naphtha, solvent
Organic solvents, Stoddard solvent
Petroleum distillate fractions
Solvents, naphthas
Stoddard solvent (ACGIH:OSHA)
White spirits

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /human	100 ppm	mild	ENTOX* -,100,2005
eye /rabbit	500 mg/24H	moderate	ATDAEI 1,32,1990

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
inhalation/cat	Lowest published lethal concentration: 1700 ppm/7H	Behavioral: Tremor Behavioral: Convulsions or effect on seizure threshold	TXAPA9 32,282,1975
inhalation/Dog	Lethal concentration: >8 gm/m³/8H-continuous	Behavioral: Tremor Behavioral: Convulsions or effect on seizure threshold	TXAPA9 32,282,1975
inhalation/Dog	Lowest published lethal concentration: 8000 mg/m³/3H	Behavioral: Alteration of classical conditioning	VCVPS* -,80,1998
inhalation/rat	lethal concentration (50 percent kill): >1400 ppm/8H		ENTOX* ,100,2005
inhalation/rat	Lowest published lethal concentration: 8200 mg/m³/8H	Behavioral: Tremor	VCVPS* -,80,1998
inhalation/rat	Lethal concentration: >5500 mg/m³/4H	Behavioral: Somnolence (general depressed activity)	ATDAEI 1,32,1990
oral/rat	Lethal dose: >5 gm/kg	Behavioral: Somnolence (general depressed activity)	ATDAEI 1,32,1990
skin/rabbit	Lethal dose: >3 gm/kg		ATDAEI 1,32,1990

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	lowest published toxic concentration: 330 ppm/65D- intermittent	Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) Blood: Other changes	TXAPA9 32,282,1975
inhalation/rat	lowest published toxic concentration: 480 mg/m³/65D- intermittent	Blood: Normocytic anemia	VCVPS* -,81,1998
inhalation/rat	lowest published toxic concentration: 1100 mg/m³/65D- intermittent	Kidney, Ureter, and Bladder: Renal function tests depressed Blood: Normocytic anemia	VCVPS* -,81,1998
skin/rabbit	lowest published toxic dose: 2 gm/kg/4W- intermittent	Skin: After systemic exposure: Dermatitis, other	NTIS** OTS0533989

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 100 ppm	DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEW		TOLED5 128,85,2002
TOXICOLOGY REVIEW		ENTOX* -,100,2005
TOXICOLOGY REVIEW		NTAPM* -,711,1995
TOXICOLOGY REVIEW		NTAPM* -,727,1995
TOXICOLOGY REVIEW		NTAPM* -,747,1995
TOXICOLOGY REVIEW		NTAPM* -,753,1995

Standards and Regulations

Organization	Standard	Reference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 790 mg/m³, JUL2008
Occupational Exposure Limit-BELGIUM	time-weighted average 100 ppm (533 mg/m³), MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 25 ppm (145 mg/m³), MAY2011
Occupational Exposure Limit-ICELAND	time-weighted average 25 ppm (145 mg/m³), skin, sen, NOV2011
Occupational Exposure Limit-KOREA	time-weighted average 100 ppm (525 mg/m³), 2006
Occupational Exposure Limit-MEXICO	time-weighted average 100 ppm (523 mg/m³);short term exposure limit 200 ppm (1050 mg/m³), 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 100 ppm (525 mg/m³), JAN2002
Occupational Exposure Limit-RUSSIA	time-weighted average 300 mg(C)/m³, short term exposure limit 900 mg(C)/m³, JUN2003
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 575 mg/m³, 2003
Occupational Exposure Limit-THE PHILIPPINES	time-weighted average 200 ppm (1150 mg/m³), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	8H time-weighted average 200 ppm (1150 mg/m³)	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	8H time-weighted average 500 ppm (2900 mg/m³)	CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)	8H time-weighted average 500 ppm (2900 mg/m³)	CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)	8H time-weighted average 200 ppm (1150 mg/m³)	CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO STODDARD SOLVENT-air	time-weighted average 350 mg/m³;ceiling concentration 1800 mg/m³/15M	NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983	Hazard Code 69855; Number of Industries 404; Total Number of Facilities 142653; Number of Occupations 222; Total Number of Employees Exposed 1922235; Total Number of Female Employees Exposed 230356
National Occupational Hazard Survey 1974	Hazard Code 69855; Number of Industries 250; Total Number of Facilities 43857; Number of Occupations 135; Total Number of Employees Exposed 483167

Status in Federal Agencies

Organization	Reference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/264263)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Naphthas, 1550
OSHA ANALYTICAL METHOD #48

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health