Propane, 2-methyl-
RTECS #
TZ4300000
CAS #
Updated
September 2013
Molecular Weight
58.14
Molecular Formula
C4H10
Synonyms
1,1-Dimethylethane
2-Methylpropane
A 31 (hydrocarbon)
R 600a
Trimethylmethane
2-Methylpropane
A 31 (hydrocarbon)
R 600a
Trimethylmethane
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/Dog | lowest published toxic concentration: 70000 ppm/5M | Cardiac: Arrythmias (indlucing changes in conduction) Cardiac: Other changes | HPV330 -,-,2000 |
inhalation/human | lowest published toxic concentration: 280 mg/m3 | Brain and Coverings: Changes in surface EEG | TOVEFN (3),38,2000 |
inhalation/mammal (species unspecified) | lowest published toxic concentration: 58600 mg/m3 | Lung, Thorax, or Respiration: Other changes Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects | TOVEFN (3),38,2000 |
inhalation/mouse | Lowest published lethal concentration: 1041 gm/m3/2H | Behavioral: Excitement | JPETAB 58,74,1936 |
inhalation/mouse | lowest published toxic concentration: 500000 mg/m3/2H | Behavioral: Ataxia | TOVEFN (3),38,2000 |
inhalation/mouse | lethal concentration (16 percent kill): 530000 mg/m3/2H | Behavioral: General anesthetic | TOVEFN (3),38,2000 |
inhalation/mouse | lethal concentration (50 percent kill): 680000 mg/m3/2H | TOVEFN (3),38,2000 | |
inhalation/rat | lethal concentration (16 percent kill): 537000 mg/m3/4H | Behavioral: General anesthetic | TOVEFN (3),38,2000 |
inhalation/rat | lethal concentration (50 percent kill): 658000 mg/m3/4H | TOVEFN (3),38,2000 | |
inhalation/rat | lethal concentration (50 percent kill): 570000 ppm/15M | Behavioral: General anesthetic Behavioral: Ataxia Lung, Thorax, or Respiration: Respiratory depression | HPV330 -,-,2000 |
inhalation/rat | lowest published toxic concentration: 200000 ppm/10M | Behavioral: Excitement | HPV330 -,-,2000 |
inhalation/rat | lethal concentration (50 percent kill): 57 pph/15M | Behavioral: Tremor Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Respiratory depression | HUTODJ 1,239,1982 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-short term exposure limit 1000 ppm | DTLVS* TLV/BEI,2013 |
TOXICOLOGY REVIEW | FAZMAE 18,365,1974 | |
TOXICOLOGY REVIEW | HUTOX* -,577,1996 | |
TOXICOLOGY REVIEW | NCLNA* 16,503,1998 |
Standards and Regulations
NIOSH Documentation and Surveillance
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
EPA TSCA Section 8(d) unpublished health/safety studies | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health