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Phenol, o-sec-butyl-

RTECS #
SJ8920000
CAS #
89-72-5
See: NMAM or OSHA Methods
Updated
December 2017
Molecular Weight
150.24
Molecular Formula
C10H14O
Synonyms
2-(1-Methylpropyl)phenol
2-(2-Butyl)phenol
2-sec.Butylfenol (Czech)
2-sec-Butylphenol
o-sec-Butylphenol
o-sec-Butylphenol (ACGIH)
Phenol, 2-(1-methylpropyl)- (9CI)

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 50 µg/24H severe85JCAE -,224,1986
skin /rabbit 2 mg/24H severe85JCAE -,224,1986

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): >290 ppm/4HNTIS** OTS0572448
intraperitoneal/mouse lethal dose (50 percent kill): 63 mg/kgJMCMAR 18,868,1975
intravenous/mouse lethal dose (50 percent kill): 60 mg/kgBehavioral: SleepJMCMAR 23,1350,1980
oral/guinea pig lethal dose (50 percent kill): 600 mg/kg85INA8 5,84,1986
oral/rat lethal dose (50 percent kill): 320 mg/kgBehavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression
NTIS** OTS0572448
skin/guinea pig lethal dose (50 percent kill): 600 mg/kg85INA8 5,84,1986
skin/rabbit lethal dose (50 percent kill): 5560 mg/kgSkin: After systemic exposure: Dermatitis, otherNTIS** OTS0572448

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 5 ppm (skin)DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWMUREAV 802,38,2016

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 5 ppm (31 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 5 ppm (30 mg/m3);KZW 10 ppm (60 mg/m3), skin, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 5 ppm (31 mg/m3), Skin, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 5 ppm (30 mg/m3), skin, MAY2011
Occupational Exposure Limit-FRANCEVME 5 ppm (30 mg/m3), Skin, FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 5 ppm (30 mg/m3), skin, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 5 ppm (30 mg/m3), skin, 2006
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 5 ppm (31 mg/m3), skin, JAN2002
Occupational Exposure Limit-PERUtime-weighted average 5 ppm (31 mg/m3), JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 5 ppm (30 mg/m3), skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 30 mg/m3, Skin, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 5 ppm (31 mg/m3), skin, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO o-sec-BUTYLPHENOL-air10H time-weighted average 5 ppm (Sk)NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974Hazard Code 83612; Number of Industries 2; Total Number of Facilities 41; Number of Occupations 2; Total Number of Employees Exposed 316

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
Page last reviewed: November 16, 2018