Isocyanic acid, 1,5-naphthylene ester

RTECS #

NQ9600000

CAS #

3173-72-6
See: NMAM or OSHA Methods

Updated

July 2013

Molecular Weight

210.20

Molecular Formula

C₁₂H₆N₂O₂

Synonyms

1,5-Diisocyanatonaphthalene
1,5-Naphthalene diisocyanate
1,5-Naphthyl diisocyanate
Desmodur 15
Naphthalene, 1,5-diisocyanato- (9CI)

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
inhalation/rat	lethal concentration (50 percent kill): 270 mg/m³/4H	Lung, Thorax, or Respiration: Dyspnea Lung, Thorax, or Respiration: Cyanosis Nutritional and Gross Metabolic: Body temperature decrease	NTIS** OTS0572846
inhalation/rat	Lowest published lethal concentration: 281 mg/m³/4H		ARTODN 78,243,2004

Organization	Standard	Reference
International Agency for Research on Cancer (IARC)	Cancer Review:Animal No Adequate Data	IMEMDT 19,303,1979
International Agency for Research on Cancer (IARC)	Cancer Review:Animal No Adequate Data	IMEMDT 71,1515,1999
International Agency for Research on Cancer (IARC)	Cancer Review:Human No Adequate Data	IMEMDT 19,303,1979
International Agency for Research on Cancer (IARC)	Cancer Review:Human No Adequate Data	IMEMDT 71,1515,1999
International Agency for Research on Cancer (IARC)	Cancer Review:Group 3	IMEMDT 71,1515,1999

Organization	Standard	Reference
Occupational Exposure Limit-AUSTRALIA	time-weighted average 0.02 mg(NCO)/m³, short term exposure limit 0.07 mg(NCO)/m³, JUL2008
Occupational Exposure Limit-AUSTRIA	MAK-TMW 0.01 ppm (0.09 mg/m³);KZW 0.02 ppm (0.18 mg/m³), sen, 2007
Occupational Exposure Limit-DENMARK	time-weighted average 0.005 ppm (0.04 mg/m³), MAY2011
Occupational Exposure Limit-FRANCE	VME 0.01 ppm (0.095 mg/m³), VLE 0.02 ppm (0.19 mg/m³), FEB2006
Occupational Exposure Limit-HUNGARY	time-weighted average 0.09 mg/m³, short term exposure limit 0.09 mg/m³, SEP2000
Occupational Exposure Limit-ICELAND	time-weighted average 0.005 ppm (0.04 mg/m³), short term exposure limit 0.01 ppm (0.09 mg/m³), skin, sen, NOV2011
Occupational Exposure Limit-NORWAY	time-weighted average 0.005 ppm (0.04 mg/m³), JAN1999
Occupational Exposure Limit-PERU	time-weighted average 0,005 ppm (0,042 mg/m³), JUL2005
Occupational Exposure Limit-SWEDEN	time-weighted average 0.002 ppm (0.017 mg/m³), ceiling concentration 0.005 ppm (0.044 mg/m³), Sen, JUN2005
Occupational Exposure Limit-SWITZERLAND	ceiling concentration 0.02 mg(NCO)/m³, skin, sen, JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 0.04 mg/m³, 2003

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO NDI-air	10H time-weighted average 0.04 mg/m³;ceiling concentration 0.17 mg/m³/10M	NIOSH* DHHS #92-100,1992

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Isocyanates, monomeric, 5521

Page last reviewed: November 16, 2018