Decaborane(14)

RTECS #

HD1400000

CAS #

17702-41-9; 1304-02-5
See: NMAM or OSHA Methods

Updated

September 2013

Molecular Weight

122.24

Molecular Formula

B₁₀H₁₄

Synonyms

Boron hydride (B10H14)
Decaborane
Decaborane (ACGIH:OSHA)
Decaborane(14) fumes
nido-Decaborane(14)
Tetradecahydrodecaborane

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
eye/rabbit	lowest published toxic dose: 0.01 mg/kg/5M	Eye: Conjunctiva irritation Eye: Corneal damage	VCVN1* -,201,1988
inhalation/mouse	lethal concentration (50 percent kill): 12 ppm/4H	Eye: Other eye effects Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia	NTIS** AD224-006
inhalation/mouse	lethal concentration (50 percent kill): 30 mg/m³		VCVN1* -,199,1988
inhalation/rat	lethal concentration (50 percent kill): 110 mg/m³/4H		VCVN1* -,199,1988
inhalation/rat	lethal concentration (50 percent kill): 46 ppm/4H	Behavioral: Convulsions or effect on seizure threshold Liver: Other changes Kidney, Ureter, and Bladder: Other changes	AMIHAB 17,362,1958
intraperitoneal/mouse	lethal dose (50 percent kill): 33 mg/kg	Behavioral: Convulsions or effect on seizure threshold Behavioral: Ataxia Lung, Thorax, or Respiration: Cyanosis	AMIHAB 11,132,1955
intraperitoneal/mouse	lethal dose (50 percent kill): 33 mg/kg	Behavioral: Coma	VCVN1* -,199,1988
intraperitoneal/rabbit	lethal dose (50 percent kill): 28 mg/kg	Behavioral: Coma	VCVN1* -,199,1988
intraperitoneal/rabbit	lethal dose (50 percent kill): 28 mg/kg		AMIHBC 8,335,1953
intraperitoneal/rat	lethal dose (50 percent kill): 23 mg/kg		AMIHBC 8,335,1953
intraperitoneal/rat	lethal dose (50 percent kill): 23 mg/kg	Behavioral: Coma	VCVN1* -,199,1988
oral/mouse	lethal dose (50 percent kill): 41 mg/kg	Eye: Corneal damage Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Cyanosis	AMIHAB 11,132,1955
oral/rat	lethal dose (50 percent kill): 64 mg/kg		MLSR** #8,1951
oral/rat	lethal dose (50 percent kill): 64 mg/kg	Behavioral: Coma	VCVN1* -,199,1988
skin/cat	lethal dose (50 percent kill): 126 mg/kg	Behavioral: Convulsions or effect on seizure threshold Liver: Fatty liver degeneration Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)	STGNBT -,60,1999
skin/cat	lethal dose (50 percent kill): 126 mg/kg/4H		VCVN1* -,201,1988
skin/guinea pig	lethal dose (50 percent kill): 158 mg/kg/4H		VCVN1* -,201,1988
skin/guinea pig	lethal dose (50 percent kill): 158 mg/kg	Behavioral: Convulsions or effect on seizure threshold Liver: Fatty liver degeneration Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)	STGNBT -,60,1999
skin/mouse	lethal dose (50 percent kill): 317 mg/kg	Behavioral: Convulsions or effect on seizure threshold Liver: Fatty liver degeneration Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)	STGNBT -,60,1999
skin/mouse	lethal dose (50 percent kill): 317 mg/kg/4H		VCVN1* -,201,1988
skin/rabbit	lethal dose (50 percent kill): 57 mg/kg/4H		VCVN1* -,201,1988
skin/rabbit	lethal dose (50 percent kill): 71 mg/kg	Behavioral: Altered sleep time (including change in righting reflex) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	AMIHAB 11,132,1955
skin/rat	lethal dose (50 percent kill): 740 mg/kg	Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Dyspnea	AMIHAB 11,132,1955
skin/rat	lethal dose (50 percent kill): 740 mg/kg/4H		VCVN1* -,201,1988

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
inhalation/mouse	lowest published toxic concentration: 22 mg/m³/5H/10D- intermittent	Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	VCVN1* -,199,1988
inhalation/rat	lowest published toxic concentration: 22 mg/m³/5H/135D- intermittent	Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	VCVN1* -,199,1988
oral/rabbit	lowest published toxic dose: 1050 µg/kg/21D- intermittent	Brain and Coverings: Other degenerative changes Vascular: Other changes Lung, Thorax, or Respiration: Other changes	STGNBT -,60,1999
oral/rat	lowest published toxic dose: 9100 µg/kg/26W- intermittent	Brain and Coverings: Other degenerative changes Behavioral: Somnolence (general depressed activity) Blood: Pigmented or nucleated red blood cells	STGNBT -,60,1999

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 0.05 ppm;short term exposure limit 0.15 ppm (skin)	DTLVS* TLV/BEI,2013

Standards and Regulations

Organization	Standard	Reference
Mine Safety and Health Administration (MSHA) STANDARD-air	time-weighted average 0.05 ppm (0.3 mg/m³) (skin)	DTLVS* 3,68,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 005 ppm (0.25 mg/m³), short term exposure limit 0.15 ppm (0.75 mg/m³), JUL2008
Occupational Exposure Limit-AUSTRIA	MAK-TMW 0.05 ppm (0.3 mg/m³);KZW 0.1 ppm (0.6 mg/m³), skin, 2007
Occupational Exposure Limit-BELGIUM	time-weighted average 0.05 ppm (0.25 mg/m³), MAR2002
Occupational Exposure Limit-BELGIUM	short term exposure limit 0.15 ppm (0.76 mg/m³), Skin, MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 0.05 ppm (0.3 mg/m³), skin, MAY2011
Occupational Exposure Limit-FINLAND	time-weighted average 0.05 ppm (0.25 mg/m³), short term exposure limit 0.15 ppm (0.76 mg/m³), skin, NOV2011
Occupational Exposure Limit-FRANCE	VME 0.05 ppm (0.3 mg/m³), Skin, FEB2006
Occupational Exposure Limit-GERMANY	MAK 0.05 ppm (0.25 mg/m³), 2011
Occupational Exposure Limit-HUNGARY	time-weighted average 0.3 mg/m³, short term exposure limit 0.3 mg/m³, Skin, SEP2000
Occupational Exposure Limit-ICELAND	time-weighted average 0.05 ppm (0.3 mg/m³), skin, NOV2011
Occupational Exposure Limit-KOREA	time-weighted average 0.05 ppm (0.3 mg/m³), short term exposure limit 0.15 ppm (0.9 mg/m³), skin, 2006
Occupational Exposure Limit-MEXICO	time-weighted average 0.05 ppm (0.3 mg/m³);short term exposure limit 0.15 ppm (skin), 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 0.05 ppm (0.25 mg/m³), skin, JAN2002
Occupational Exposure Limit-NORWAY	time-weighted average 0.05 ppm (0.3 mg/m³), JAN1999
Occupational Exposure Limit-PERU	time-weighted average 0.05 ppm (0.25 mg/m³); short term exposure limit 0.15 ppm (0.75 mg/m³), JUL2005
Occupational Exposure Limit-SWITZERLAND	MAK-week 0.05 ppm (0.25 mg/m³), KZG-week 0.1 ppm (0.5 mg/m³), skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 0.3 mg/m³, 2003
Occupational Exposure Limit-THE PHILIPPINES	time-weighted average 0.05 ppm (0.3 mg/m³), Skin, JAN1993
Occupational Exposure Limit-TURKEY	time-weighted average 0.05 ppm (0.3 mg/m³), Skin, JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	8H time-weighted average 0.05 ppm (0.3 mg/m³) (skin)	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	8H time-weighted average 0.05 ppm (0.3 mg/m³) (skin)	CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)	8H time-weighted average 0.05 ppm (0.3 mg/m³) (skin)	CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)	8H time-weighted average 0.05 ppm (0.3 mg/m³) (skin)	CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DECABORANE-air	10H time-weighted average 0.05 ppm (Sk);short term exposure limit 0.15 ppm (Sk)	NIOSH* DHHS #95-121,1995

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health