Cyclohexanone, 2-methyl-
RTECS #
GW1750000
CAS #
Updated
September 2013
Molecular Weight
112.19
Molecular Formula
C7H12O
Synonyms
2-Methyl-cyclohexanon (German, Dutch)
alpha-Methylcyclohexanone
o-Methylcyclohexanone
alpha-Methylcyclohexanone
o-Methylcyclohexanone
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
inhalation/rat | Lowest published lethal concentration: 2800 ppm/4H | AIHAAP 30,470,1969 | |
intraperitoneal/mouse | lethal dose (50 percent kill): 200 mg/kg | NTIS** AD691-490 | |
intravenous/mouse | lowest published lethal dose: 270 mg/kg | Cardiac: Change in rate Vascular: BP lowering not characterized in autonomic section | COREAF 236,633,1953 |
oral/rat | lethal dose (50 percent kill): 2140 µL/kg | AIHAAP 30,470,1969 | |
skin/rabbit | lethal dose (50 percent kill): 1770 µL/kg | AIHAAP 30,470,1969 |
Reviews
Organization | Standard | Reference |
---|---|---|
American Conference of Governmental Industrial Hygienists (ACGIH) | Threshold Limit Value-time-weighted average 50 ppm;short term exposure limit 75 ppm (skin) | DTLVS* TLV/BEI,2013 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Mine Safety and Health Administration (MSHA) STANDARD-air | time-weighted average 50 ppm (230 mg/m3) (skin) | DTLWS* 3,23,1973 |
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV; | ||
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV | ||
Occupational Exposure Limit-AUSTRALIA | time-weighted average 50 ppm (229 mg/m3), short term exposure limit 75 ppm (344 mg/m3), JUL2008 | |
Occupational Exposure Limit-AUSTRIA | MAK-TMW 50 ppm (230 mg/m3);KZW 200 ppm (920 mg/m3), skin, 2007 | |
Occupational Exposure Limit-BELGIUM | time-weighted average 50 ppm (232 mg/m3), MAR2002 | |
Occupational Exposure Limit-BELGIUM | short term exposure limit 75 ppm (349 mg/m3), Skin, MAR2002 | |
Occupational Exposure Limit-DENMARK | time-weighted average 50 ppm (230 mg/m3), skin, MAY2011 | |
Occupational Exposure Limit-FINLAND | time-weighted average 50 ppm (230 mg/m3), short term exposure limit 75 ppm (350 mg/m3), skin, NOV2011 | |
Occupational Exposure Limit-FRANCE | VME 50 ppm (230 mg/m3), Skin, FEB2006 | |
Occupational Exposure Limit-ICELAND | time-weighted average 50 ppm (230 mg/m3), skin, NOV2011 | |
Occupational Exposure Limit-KOREA | time-weighted average 50 ppm (230 mg/m3), short term exposure limit 75 ppm (345 mg/m3), skin, 2006 | |
Occupational Exposure Limit-MEXICO | time-weighted average 50 ppm (230 mg/m3);short term exposure limit 75 ppm (skin), 2004 | |
Occupational Exposure Limit-NEW ZEALAND | time-weighted average 50 ppm (229 mg/m3); short term exposure limit 75 ppm (344 mg/m3), skin, JAN2002 | |
Occupational Exposure Limit-NORWAY | time-weighted average 25 ppm (115 mg/m3), JAN1999 | |
Occupational Exposure Limit-PERU | time-weighted average 50 ppm (229 mg/m3); short term exposure limit 75 ppm (344 mg/m3), JUL2005 | |
Occupational Exposure Limit-POLAND | MAC(time-weighted average) 50 mg/m3, MAC(short term exposure limit) 340 mg/m3, JAN1999 | |
Occupational Exposure Limit-RUSSIA | time-weighted average 50 ppm, JUN2003 | |
Occupational Exposure Limit-SWITZERLAND | MAK-week 50 ppm (230 mg/m3), KZG-week 100 ppm (460 mg/m3), skin, JAN2011 | |
Occupational Exposure Limit-THE NETHERLANDS | MAC-TGG 230 mg/m3, Skin, 2003 | |
Occupational Exposure Limit-THE PHILIPPINES | time-weighted average 100 ppm (460 mg/m3), Skin, JAN1993 | |
Occupational Exposure Limit-TURKEY | time-weighted average 100 ppm (460 mg/m3), Skin, JAN1993 | |
Occupational Exposure Limit-UNITED KINGDOM | time-weighted average 50 ppm (233 mg/m3);short term exposure limit 75 ppm (350 mg/m3), OCT2007 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | 8H time-weighted average 100 ppm (460 mg/m3) (skin) | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) | 8H time-weighted average 100 ppm (460 mg/m3) (skin) | CFRGBR 41,50-204.50,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) | 8H time-weighted average 100 ppm (460 mg/m3) (skin) | CFRGBR 29,1910.1000,1994 |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) | 8H time-weighted average 100 ppm (460 mg/m3) (skin) | CFRGBR 29,1915.1000,1993 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO THE CHEMICAL-air | 10H time-weighted average 50 ppm (Sk);short term exposure limit 75 ppm (Sk) | NIOSH* DHHS #92-100,1992 |
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
NIOSH Analytical Method, 1994: Methylcyclohexanone, 2521 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health