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Cyanamide, calcium salt (1:1)

RTECS #
GS6000000
CAS #
156-62-7
See: NMAM or OSHA Methods
Updated
September 2013
Molecular Weight
80.11
Molecular Formula
CN2·Ca
Synonyms
Alzodef
Calcium carbimide
Calcium cyanamid
Calcium cyanamide
Calcium cyanamide (ACGIH)
CCC
Cyanamid granular
Cyanamide calcique (French)
CY-L 500
Dormex
Lime-nitrogen
NCI-C02937
Nitrogen lime
Nitrolim
Nitrolime
USAF CY-2

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium1 mg/plate (+enzymatic activation step)ENMUDM 5(Suppl 1),3,1983

Tumorigenic Data and References

Route/OrganismDoseEffectReference
oral/mouse lowest published toxic dose: 170 gm/kg/2Y- continuousTumorigenic: Equivocal tumorigenic agent by RTECS criteria

Vascular: Tumors
NCITR* NCI-TR-163,1979

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): >150 mg/m3/4H85JFAN A053,1984
inhalation/rat lowest published toxic concentration: 3000 mg/m3/20MBehavioral: Somnolence (general depressed activity)VCVN1* -,346,1988
intraperitoneal/mouse lethal dose (50 percent kill): 100 mg/kgNTIS** AD277-689
intravenous/mouse lethal dose (50 percent kill): 282 mg/kgNIIRDN 6,304,1982
intravenous/rat lethal dose (50 percent kill): 125 mg/kgNIIRDN 6,304,1982
oral/guinea pig lethal dose (50 percent kill): 220 mg/kgBehavioral: Irritability

Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,346,1988
oral/human lowest published lethal dose: 571 mg/kg34ZIAG -,149,1969
oral/mouse lethal dose (50 percent kill): 334 mg/kgBehavioral: Irritability

Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,346,1988
oral/mouse lethal dose (50 percent kill): 334 mg/kgNIIRDN 6,304,1982
oral/rabbit lethal dose (50 percent kill): 350 mg/kgBehavioral: Irritability

Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,346,1988
oral/rabbit lethal dose (50 percent kill): 1400 mg/kgPCOC** -,174,1966
oral/rat lethal dose (50 percent kill): 158 mg/kgNIIRDN 6,304,1982
oral/rat lethal dose (50 percent kill): 250 mg/kgBehavioral: Irritability

Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea
VCVN1* -,346,1988
skin/rabbit lethal dose (50 percent kill): 590 mg/kg37ASAA 7,291,1979
unreported route/human lowest published lethal dose: 571.4 mg/kgVCVN1* -,346,1988
unreported route/rat lethal dose (50 percent kill): 1 gm/kgGUCHAZ 6,73,1973

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/rat lowest published toxic dose: 250 mg/kg/10D- intermittentBehavioral: Tremor

Lung, Thorax, or Respiration: Dyspnea

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
VCVN1* -,347,1988

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 mg/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWMUREAV 584,1,2005

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESCancelledRBREV* -,299,1998
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.5 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 0.5 mg/m3;KZW 5 mg/m3, inhal, skin, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.5 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg/m3, MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 0.5 mg/m3, short term exposure limit 1.5 mg/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 0.5 mg/m3, FEB2006
Occupational Exposure Limit-GERMANYMAK 1 mg/m3, inhal, skin, 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 1 mg/m3, short term exposure limit 4 mg/m3, Skin, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 0.5 mg/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.5 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg/m3;short term exposure limit 1 mg/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.5 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0.5 mg/m3, JUL2005
Occupational Exposure Limit-RUSSIAshort term exposure limit 1 mg/m3, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 0.5 mg/m3, KZG-week 1.0 mg/m3, resp, skin, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.5 mg/m3, 2003
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.5 mg/m3;short term exposure limit 1 mg/m3, OCT2007

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CALCIUM CYANAMIDE-air10H time-weighted average 0.5 mg/m3NIOSH* DHHS #95-121,1995
National Occupational Exposure Survey 1983Hazard Code 15730; Number of Industries 2; Total Number of Facilities 249; Number of Occupations 3; Total Number of Employees Exposed 4390
National Occupational Hazard Survey 1974Hazard Code 15730; Number of Industries 2; Total Number of Facilities 287; Number of Occupations 2; Total Number of Employees Exposed 12607

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
NCI Carcinogenesis Bioassay (feed);no evidence:mouse,ratNCITR* NCI-TR-163,1979
Page last reviewed: November 16, 2018