Barium(II) nitrate (1:2)

RTECS #

CQ9625000

CAS #

10022-31-8
See: NMAM or OSHA Methods

Updated

September 2013

Molecular Weight

261.36

Molecular Formula

N₂O₆·Ba

Synonyms

Barium dinitrate
Dusicnan barnaty (Czech)
Nitrate de baryum (French)
Nitric acid, barium salt

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /rabbit	100 mg/24H	moderate	28ZPAK -,10,1972
skin /rabbit	500 mg/24H	mild	28ZPAK -,10,1972

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
In Vitro/Chicken, neurons	Inhibitor Concentration (50 percent kill): 4810 µmol/L/21H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	TIVIEQ 7,653,1993
In Vitro/Chicken, neurons	Inhibitor Concentration (10 percent kill): 2681 µmol/L/21H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	TIVIEQ 7,653,1993
In Vitro/Chicken, neurons	Inhibitor Concentration (50 percent kill): 4630 µmol/L/20H	In Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.	TIVIEQ 7,653,1993
In Vitro/Chicken, neurons	Inhibitor Concentration (10 percent kill): 2600 µmol/L/20H	In Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.	TIVIEQ 7,653,1993
intraperitoneal/mouse	lethal dose (50 percent kill): 293 mg/kg	Autonomic Nervous System: Other (direct) parasympathomimetic Behavioral: Muscle weakness Gastrointestinal: Nausea or vomiting	GTPZAB 28(6),45,1984
intraperitoneal/rat	lethal dose (50 percent kill): 293 mg/kg	Behavioral: Somnolence (general depressed activity) Behavioral: Tetany	VCVN1* -,136,1988
intravenous/mouse	lethal dose (50 percent kill): 16 mg/kg		TXAPA9 22,150,1972
oral/Dog	lowest published lethal dose: 800 mg/kg		YKYUA6 31,1247,1980
oral/mammal (species unspecified)	lethal dose (50 percent kill): 390 mg/kg	Autonomic Nervous System: Other (direct) parasympathomimetic Behavioral: Muscle weakness Gastrointestinal: Nausea or vomiting	GTPZAB 28(6),45,1984
oral/man	lowest published toxic dose: 83 mg/kg	Peripheral Nerve and Sensation: Paresthesia Behavioral: Muscle weakness Nutritional and Gross Metabolic: Changes in: K	JTCTDW 38,254,2000
oral/mouse	lethal dose (50 percent kill): 266 mg/kg		EVHPAZ 106(Suppl 2),497,1998
oral/rabbit	lowest published lethal dose: 150 mg/kg		YKYUA6 31,1247,1980
oral/rat	lethal dose (50 percent kill): 355 mg/kg		28ZPAK -,10,1972
oral/rat	lethal dose (50 percent kill): 390 mg/kg	Behavioral: Somnolence (general depressed activity) Behavioral: Tetany	VCVN1* -,136,1988
parenteral/rabbit	lowest published lethal dose: 30 mg/kg	Gastrointestinal: Hypermotility, diarrhea Kidney, Ureter, and Bladder: Urine volume increased	MELAAD 30,44,1939
subcutaneous/mouse	lowest published lethal dose: 10 mg/kg		NTIS** AEC-TR-6710

Reviews

Organization	Standard	Reference
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-time-weighted average 0.5 mg(Ba)/m3	DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)	Threshold Limit Value-Not classifiable as a human carcinogen	DTLVS* TLV/BEI,2013

Standards and Regulations

Organization	Standard	Reference
Mine Safety and Health Administration (MSHA) STANDARD-air	time-weighted average 0.5 mg(Ba)/m³	DTLVS* 3,21,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIA	time-weighted average 0.5 mg(Ba)/m³, JUL2008
Occupational Exposure Limit-BELGIUM	time-weighted average 0.5 mg(Ba)/m³, MAR2002
Occupational Exposure Limit-DENMARK	time-weighted average 0.5 mg(Ba)/m³, MAY2011
Occupational Exposure Limit-EC	time-weighted average 0.5 mg(Ba)/m³, FEB2006
Occupational Exposure Limit-FINLAND	time-weighted average 0.5 mg(Ba)/m³, NOV2011
Occupational Exposure Limit-FRANCE	VME 0.5 mg(Ba)/m³, FEB2006
Occupational Exposure Limit-HUNGARY	time-weighted average 0.5 mg(Ba)/m³, short term exposure limit 2 mg(Ba)/m³, SEP2000
Occupational Exposure Limit-KOREA	time-weighted average 0.5 mg(Ba)/m³, 2006
Occupational Exposure Limit-MEXICO	time-weighted average 0.5 mg(Ba)/m³, 2004
Occupational Exposure Limit-NEW ZEALAND	time-weighted average 0.5 mg(Ba)/m³, JAN2002
Occupational Exposure Limit-NORWAY	time-weighted average 0.5 mg(Ba)/m³, JAN1999
Occupational Exposure Limit-POLAND	time-weighted average 0.5 mg(Ba)/m³, short term exposure limit 1.5 mg(Ba)/m³, JAN1999
Occupational Exposure Limit-RUSSIA	time-weighted average 0.5 mg/m³, short term exposure limit 1.5 mg/m³, JUN2003
Occupational Exposure Limit-SWEDEN	time-weighted average 0.5 mg(Ba)/m³, JUN2005
Occupational Exposure Limit-SWITZERLAND	MAK-week 0.5 mg(Ba)/m³, KZG-week 1 mg(Ba)/m³, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDS	MAC-TGG 0.5 mg(Ba)/m³, 2003
Occupational Exposure Limit-THE PHILIPPINES	time-weighted average 0.5 mg(Ba)/m³, JAN1993
Occupational Exposure Limit-TURKEY	time-weighted average 0.5 mg(Ba)/m³, JAN1993
Occupational Exposure Limit-UNITED KINGDOM	time-weighted average 0.5 mg(Ba)/m³, sen, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	8H time-weighted average 0.5 mg(Ba)/m³	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	8H time-weighted average 0.5 mg(Ba)/m³	CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)	8H time-weighted average 0.5 mg(Ba)/m³	CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)	8H time-weighted average 0.5 mg(Ba)/m³	CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Occupational Exposure Survey 1983	Hazard Code 81720; Number of Industries 23; Total Number of Facilities 600; Number of Occupations 26; Total Number of Employees Exposed 19320; Total Number of Female Employees Exposed 5165
National Occupational Hazard Survey 1974	Hazard Code 81720; Number of Industries 12; Total Number of Facilities 542; Number of Occupations 13; Total Number of Employees Exposed 2705

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health