Aniline, N,N-dimethyl-p-phenylazo-
RTECS #
BX7350000
CAS #
Updated
September 2018
Molecular Weight
225.32
Molecular Formula
C14H15N3
Synonyms
4-(N,N-Dimethylamino)azobenzene
4-(Phenylazo)-N,N-dimethylaniline
4-Dimethylaminoazobenzene (OSHA)
4-Dimethylaminoazobenzol
4-Dimethylaminophenylazobenzene
Atul Fast Yellow R
Azobenzene, p-dimethylamino-
Benzenamine, N,N-dimethyl-4-(phenylazo)- (9CI)
Benzeneazodimethylaniline
Brilliant Fast Oil Yellow
Brilliant Fast Spirit Yellow
Brilliant Fast Yellow
Brilliant Oil Yellow
Butter Yellow
C.I. 11020
C.I. Solvent Yellow 2
Cerasine Yellow GG
DAB
DAB (carcinogen)
Dimethyl Yellow
Dimethyl Yellow Analar
Dimethyl Yellow N,N-dimethylaniline
DMAB
Enial Yellow 2G
Fast Oil Yellow B
Fast Yellow
Fat Yellow
Fat Yellow A
Fat Yellow AD OO
Fat Yellow ES
Fat Yellow ES Extra
Fat Yellow Extra Conc.
Fat Yellow R
Fat Yellow R (8186)
Grasal Brilliant Yellow
Iketon Yellow Extra
Jaune de beurre (French)
Methyl Yellow
N,N-Dimethyl-4-(phenylazo)benzamine
N,N-Dimethyl-4-(phenylazo)benzenamine
N,N-Dimethyl-4-aminoazobenzene
N,N-Dimethyl-p-aminoazobenzene
N,N-Dimethyl-p-azoaniline
N,N-Dimethyl-p-phenylazoaniline
Oil Yellow 20
Oil Yellow 2625
Oil Yellow 2G
Oil Yellow 7463
Oil Yellow BB
Oil Yellow D
Oil Yellow DN
Oil Yellow FF
Oil Yellow FN
Oil Yellow G
Oil Yellow G-2
Oil Yellow GG
Oil Yellow GR
Oil Yellow II
Oil Yellow N
Oil Yellow PEL
Oil Yellow S
Oleal Yellow 2G
Organol Yellow ADM
Orient Oil Yellow GG
P.D.A.B.
p-Dimethylaminoazobenzen (Czech)
p-Dimethylaminoazobenzene
p-Dimethylamino-azobenzol (German)
Petrol Yellow WT
RCRA waste number U093
Resinol Yellow GR
Resoform Yellow GGA
Silotras Yellow T2G
Somalia Yellow A
Stear Yellow JB
Sudan GG
Sudan Yellow
Sudan Yellow GG
Sudan Yellow GGA
Toyo Oil Yellow G
USAF EK-338
Waxoline Yellow AD
Waxoline Yellow ADS
Yellow G soluble in grease
Zlut maselna (Czech)
Zlut rozpoustedlova 2 (Czech)
4-(Phenylazo)-N,N-dimethylaniline
4-Dimethylaminoazobenzene (OSHA)
4-Dimethylaminoazobenzol
4-Dimethylaminophenylazobenzene
Atul Fast Yellow R
Azobenzene, p-dimethylamino-
Benzenamine, N,N-dimethyl-4-(phenylazo)- (9CI)
Benzeneazodimethylaniline
Brilliant Fast Oil Yellow
Brilliant Fast Spirit Yellow
Brilliant Fast Yellow
Brilliant Oil Yellow
Butter Yellow
C.I. 11020
C.I. Solvent Yellow 2
Cerasine Yellow GG
DAB
DAB (carcinogen)
Dimethyl Yellow
Dimethyl Yellow Analar
Dimethyl Yellow N,N-dimethylaniline
DMAB
Enial Yellow 2G
Fast Oil Yellow B
Fast Yellow
Fat Yellow
Fat Yellow A
Fat Yellow AD OO
Fat Yellow ES
Fat Yellow ES Extra
Fat Yellow Extra Conc.
Fat Yellow R
Fat Yellow R (8186)
Grasal Brilliant Yellow
Iketon Yellow Extra
Jaune de beurre (French)
Methyl Yellow
N,N-Dimethyl-4-(phenylazo)benzamine
N,N-Dimethyl-4-(phenylazo)benzenamine
N,N-Dimethyl-4-aminoazobenzene
N,N-Dimethyl-p-aminoazobenzene
N,N-Dimethyl-p-azoaniline
N,N-Dimethyl-p-phenylazoaniline
Oil Yellow 20
Oil Yellow 2625
Oil Yellow 2G
Oil Yellow 7463
Oil Yellow BB
Oil Yellow D
Oil Yellow DN
Oil Yellow FF
Oil Yellow FN
Oil Yellow G
Oil Yellow G-2
Oil Yellow GG
Oil Yellow GR
Oil Yellow II
Oil Yellow N
Oil Yellow PEL
Oil Yellow S
Oleal Yellow 2G
Organol Yellow ADM
Orient Oil Yellow GG
P.D.A.B.
p-Dimethylaminoazobenzen (Czech)
p-Dimethylaminoazobenzene
p-Dimethylamino-azobenzol (German)
Petrol Yellow WT
RCRA waste number U093
Resinol Yellow GR
Resoform Yellow GGA
Silotras Yellow T2G
Somalia Yellow A
Stear Yellow JB
Sudan GG
Sudan Yellow
Sudan Yellow GG
Sudan Yellow GGA
Toyo Oil Yellow G
USAF EK-338
Waxoline Yellow AD
Waxoline Yellow ADS
Yellow G soluble in grease
Zlut maselna (Czech)
Zlut rozpoustedlova 2 (Czech)
Mutation Data and Reference
System Test | Route/Organism/Tissue | Dose | Reference |
---|---|---|---|
body fluid assay | Salmonella typhimurium/rat | 600 mg/kg | NATUAS 249,850,1974 |
Cytogenetic Analysis | oral/rat | 756 mg/kg/3W | JNCIAM 54,1245,1975 |
Cytogenetic Analysis | oral/mouse | 4950 mg/kg/30D- intermittent | MUREAV 587,1,2005 |
Cytogenetic Analysis | oral/mouse | 4950 mg/kg/30D-continuous | FCTOD7 46,1474,2008 |
DNA adduct | oral/rat | 300 mg/kg | CNREA8 36,4647,1976 |
DNA adduct | intraperitoneal/rat | 150 mg/kg | NATUAS 213,1206,1967 |
DNA adduct | intraperitoneal/mouse | 120 mg/kg | CNREA8 40,2493,1980 |
DNA adduct | skin/mouse | 192 µmol/kg | CRNGDP 5,231,1984 |
DNA Damage | intraperitoneal/mouse | 200 mg/kg | MUREAV 493,39,2001 |
DNA Damage | oral/mouse | 500 mg/kg | MUREAV 493,39,2001 |
DNA inhibition | intraperitoneal/mouse | 20 gm/kg | ARGEAR 51,605,1981 |
DNA inhibition | oral/mouse | 100 mg/kg | MUREAV 46,305,1977 |
DNA inhibition | HeLa cell/human | 100 µmol/L | MUREAV 92,427,1982 |
DNA repair | /Escherichia coli | 80 mg/L | MUREAV 119,135,1983 |
DNA repair | /Saccharomyes cerevisiae | 600 mg/L | PMRSDJ 1,502,1981 |
gene conversion and mitotic recombination | /Saccharomyes cerevisiae | 5 mg/L | PMRSDJ 1,491,1981 |
gene conversion and mitotic recombination | oral/Drosophila melanogaster | 2.0 mmol/L/48H | MUTAEX 16,385,2001 |
host-mediated assay | Salmonella typhimurium/mouse | 255 mg/kg/3H | MUREAV 45,291,1977 |
micronucleus test | intraperitoneal/mouse | 6400 µg/kg | PMRSDJ 1,686,1981 |
micronucleus test | oral/mouse | 1155 mg/kg/7D-continuous | FCTOD7 46,1474,2008 |
micronucleus test | oral/rat | 150 mg/kg/2D- intermittent | MUREAV 698,24,2010 |
micronucleus test | oral/mouse | 9900 mg/kg/60D- intermittent | MUREAV 587,1,2005 |
micronucleus test | intraperitoneal/rat | 71 mg/kg | MUREAV 583,133,2005 |
micronucleus test | oral/rat | 120 mg/kg | MUREAV 583,133,2005 |
micronucleus test | oral/rat | 700 mg/kg/14D | MUREAV 780-781,2,2015 |
morphological transform | embryo/rat | 12 mg/L | JJIND8 67,1303,1981 |
morphological transform | embryo/mouse | 89 µmol/L | MUREAV 152,113,1985 |
morphological transform | other cell types/non-mammalian species | 250 µg/L | AOHYA3 20,297,1977 |
morphological transform | fibroblast/mouse | 1 mg/L/21D (-enzymatic activation step) | EMMUEG 35,300,2000 |
morphological transform | intraperitoneal/hamster | 500 mg/kg | ARPAAQ 95,380,1973 |
morphological transform | embryo/hamster | 50 µg/L | JJIND8 67,1303,1981 |
morphological transform | kidney/hamster | 25 mg/L | PMRSDJ 1,638,1981 |
mutation in mammalian somatic cells | lymphocyte/mouse | 89 µmol/L | MUREAV 110,147,1983 |
mutation in microorganisms | lymphocyte/mouse | 6250 µg/L (+enzymatic activation step) | EMMUEG 12(Suppl 13),103,1988 |
mutation in microorganisms | /Salmonella typhimurium | 5 mg/plate (+enzymatic activation step) | AEMIDF 42,641,1981 |
mutation in microorganisms | /Salmonella typhimurium | 33 µg/plate (-enzymatic activation step) | ENMUDM 9(Suppl 9),1,1987 |
mutation in microorganisms | /Escherichia coli | 200 mg/L (+enzymatic activation step) | PMRSDJ 1,396,1981 |
other mutation test systems | intraperitoneal/mouse | 100 mg/kg | MUREAV 747,164,2012 |
sex chromosome loss and nondisjunction | /Saccharomyes cerevisiae | 50 mg/L | PMRSDJ 1,468,1981 |
sister chromatid exchange | intraperitoneal/mouse | 29 mg/kg | MUREAV 108,225,1983 |
specific locus test | other cell types/human | 50 mg/L/3H (+enzymatic activation step) | MUTAEX 24,35,2009 |
sperm morphology | oral/mouse | 9900 mg/kg/60D-continuous | FCTOD7 46,1474,2008 |
sperm morphology | intraperitoneal/mouse | 3 gm/kg/5D- intermittent | PMRSDJ 1,712,1981 |
Unscheduled DNA Synthesis | liver/mouse | 1 µmol/L | GANNA2 72,930,1981 |
Unscheduled DNA Synthesis | liver/hamster | 1 µmol/L | ENMUDM 5,1,1983 |
Unscheduled DNA Synthesis | HeLa cell/human | 10 nmol/L | CNREA8 38,2621,1978 |
Unscheduled DNA Synthesis | fibroblast/human | 4 mg/L | PMRSDJ 1,528,1981 |
Unscheduled DNA Synthesis | liver/rat | 1 µmol/L | CNREA8 46,1654,1986 |
Unscheduled DNA Synthesis | liver/rat | 1 µmol/L | JJCREP 78,505,1987 |
Reproductive Effects Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
intraperitoneal/mouse | 3 gm/kg (5D male) | Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) | PMRSDJ 1,712,1981 |
subcutaneous/mouse | 200 mg/kg (10D pregnant) | Reproductive: Specific developmental abnormalities: Musculoskeletal system | OFAJAE 36,195,1960 |
Tumorigenic Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
intraperitoneal/mouse | lowest published toxic dose: 3830 µg/kg | Tumorigenic: Neoplastic by RTECS criteria Liver: Tumors | CNREA8 44,2540,1984 |
intraperitoneal/mouse | toxic dose: 11 mg/kg | Tumorigenic: Neoplastic by RTECS criteria Liver: Tumors | CNREA8 44,2540,1984 |
multiple/mouse | lowest published toxic dose: 400 mg/kg | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors Tumorigenic: Tumors at site of application | CNREA8 1,397,1941 |
oral/Dog | lowest published toxic dose: 9600 mg/kg/69W- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, and Bladder: Bladder tumors | JNCIAM 13,1497,1953 |
oral/hamster | lowest published toxic dose: 9600 mg/kg/42W- intermittent | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Change in gall bladder structure or function Blood: Other hemolysis with or without anemia | ARPAAQ 71,566,1961 |
oral/mouse | lowest published toxic dose: 9900 mg/kg/60D- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors | FCTOD7 46,1474,2008 |
oral/rat | lowest published toxic dose: 3.24 gm/kg/90D- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors | FCTOD7 48,3281,2010 |
oral/rat | toxic dose: 800 mg/kg/64D- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors | ZEKBAI 61,327,1956 |
oral/rat | lowest published toxic dose: 5426 mg/kg/17W- continuous | Tumorigenic: Carcinogenic by RTECS criteria Liver: Tumors | CBINA8 53,107,1985 |
oral/rat | toxic dose: 2600 mg/kg/13W- continuous | Tumorigenic: Neoplastic by RTECS criteria Liver: Tumors | CNREA8 17,387,1957 |
oral/rat | toxic dose: 13 gm/kg/53W- continuous | Tumorigenic: Neoplastic by RTECS criteria Liver: Tumors | MEXPAG 4,1,1961 |
oral/rat | toxic dose: 1920 mg/kg/14W- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors | CNREA8 5,235,1945 |
oral/rat | toxic dose: 1800 mg/kg/14W- continuous | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors | CNREA8 8,141,1948 |
oral/rat | toxic dose: 2331 mg/kg/7W- intermittent | Tumorigenic: Equivocal tumorigenic agent by RTECS criteria Liver: Tumors | KTUNAA 32,229,1979 |
oral/rat | toxic dose: 17200 mg/kg/17W- continuous | Tumorigenic: Neoplastic by RTECS criteria Liver: Tumors | ARPAAQ 81,162,1966 |
oral/rat | toxic dose: 8316 mg/kg/33W- continuous | Tumorigenic: Neoplastic by RTECS criteria Liver: Tumors | JPBAA7 59,1,1947 |
oral/rat | toxic dose: 3990 mg/kg/19W- continuous | Tumorigenic: Neoplastic by RTECS criteria Lung, Thorax, or Respiration: Consolidation Liver: Tumors | GANNA2 63,131,1972 |
skin/rat | lowest published toxic dose: 1440 mg/kg/90W- intermittent | Tumorigenic: Neoplastic by RTECS criteria Skin and Appendages: Tumors | CNREA8 26,2406,1966 |
subcutaneous/mouse | lowest published toxic dose: 4000 mg/kg (15-21D pregnant) | Tumorigenic: Carcinogenic by RTECS criteria Reproductive: Tumorigenic effects: Transplacental tumorigenesis Lung, Thorax, or Respiration: Tumors | BEXBAN 78,1402,1974 |
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
intraperitoneal/mouse | lethal dose (50 percent kill): 230 mg/kg | Lung, Thorax, or Respiration: Dyspnea Lung, Thorax, or Respiration: Cyanosis | CNREA8 34,2274,1974 |
intraperitoneal/mouse | lethal dose (50 percent kill): 230 mg/kg | ENTOX* -,356,2005 | |
intraperitoneal/mouse | lowest published lethal dose: 230 mg/kg | MUREAV 747,164,2012 | |
intraperitoneal/rat | lethal dose (50 percent kill): 230 mg/kg | Lung, Thorax, or Respiration: Dyspnea Lung, Thorax, or Respiration: Cyanosis | CNREA8 34,2274,1974 |
intraperitoneal/rat | lethal dose (50 percent kill): 230 mg/kg | ENTOX* -,356,2005 | |
oral/mouse | lethal dose (50 percent kill): 300 mg/kg | ENTOX* -,53,2005 | |
oral/rat | lethal dose (50 percent kill): 200 mg/kg | ENTOX* -,53,2005 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
oral/mouse | lowest published toxic dose: 20000 mg/kg/40D- continuous | Liver: Other changes Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation) Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects | BJCAAI 86,630,2002 |
oral/mouse | lowest published toxic dose: 9900 mg/kg/60D- intermittent | Liver: Tumors Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) | MUREAV 587,1,2005 |
oral/mouse | lowest published toxic dose: 1155 mg/kg/7D- intermittent | Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases | MUREAV 587,1,2005 |
oral/mouse | lowest published toxic dose: 1155 mg/kg/7D- continuous | Liver: Other changes Kidney, Ureter, and Bladder: Other changes Blood: Changes in spleen | FCTOD7 46,1474,2008 |
oral/mouse | lowest published toxic dose: 1.75 mg/kg/5W- intermittent | Liver: Other changes Nutritional and Gross Metabolic: Changes in: Other metals Biochemical: Metabolism (intermediary): Other | TOLED5 203,40,2011 |
oral/rat | lowest published toxic dose: 1400 mg/kg/14D- intermittent | Liver: Tumors Liver: Changes in liver weight | MUREAV 780-781,2,2015 |
Reviews
Organization | Standard | Reference |
---|---|---|
International Agency for Research on Cancer (IARC) | Cancer Review:Animal Sufficient Evidence | IMEMDT 8,125,1975 |
International Agency for Research on Cancer (IARC) | Cancer Review:Human No Adequate Data | IMEMDT 8,125,1975 |
International Agency for Research on Cancer (IARC) | Cancer Review:Group 2B | IMSUDL 7,56,1987 |
TOXICOLOGY REVIEW | ALLVAR 50,77,1962 | |
TOXICOLOGY REVIEW | BJCAAI 6,270,1952 | |
TOXICOLOGY REVIEW | ADCSAJ 13,271,1970 | |
TOXICOLOGY REVIEW | JONUAI 44,345,1951 | |
TOXICOLOGY REVIEW | BLFSBY 24,129,1983 | |
TOXICOLOGY REVIEW | MUREAV 567,347,2004 | |
TOXICOLOGY REVIEW | MUREAV 578,88,2005 | |
TOXICOLOGY REVIEW | ENTOX* -,356,2005 | |
TOXICOLOGY REVIEW | MUREAV 627,10,2007 | |
TOXICOLOGY REVIEW | ENTOX* -,53,2005 | |
TOXICOLOGY REVIEW | ENTOX* -,104,2005 | |
TOXICOLOGY REVIEW | MUREAV 584,1,2005 | |
TOXICOLOGY REVIEW | MUREAV 654,114,2008 | |
TOXICOLOGY REVIEW | MUREAV 681,51,2009 | |
TOXICOLOGY REVIEW | MUTAEX 26,223,2011 | |
TOXICOLOGY REVIEW | MUREAV 733,4,2012 | |
TOXICOLOGY REVIEW | MUREAV 769,34,2014 | |
TOXICOLOGY REVIEW | MUREAV 802,1,2016 | |
TOXICOLOGY REVIEW | FCTOD7 106,609,2017 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Occupational Exposure Limit-JAPAN | 2B carc, MAY2012 | |
Occupational Exposure Limit-SWEDEN | Group A Carcinogen, JUN2005 | |
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) | see Code of Federal Regulations (CFR) 29,1926.1115 | CFRGBR 29,1926.55,1994 |
Occupational Safety and Health Administration (OSHA)-cancer suspect agent | CFRGBR 29,1910.1015,1987 |
NIOSH Documentation and Surveillance
Organization | Standard | Reference |
---|---|---|
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO 4-DIMETHYLAMINOAZOBENZENE-air | Carcinogen use 29 Code of Federal Regulations (CFR) 1910.1015 | NIOSH* DHHS #92-100,1992 |
National Occupational Exposure Survey 1983 | Hazard Code 26175; Number of Industries 2; Total Number of Facilities 56; Number of Occupations 2; Total Number of Employees Exposed 1453; Total Number of Female Employees Exposed 996 | |
National Occupational Hazard Survey 1974 | Hazard Code 26175; Number of Industries 2; Total Number of Facilities 29; Number of Occupations 2; Total Number of Employees Exposed 42 |
Status in Federal Agencies
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health