High-Resolution Mass Spectral Libraries for Opioid Analysis
Mass spectrometry is used by laboratories to confirm the presence of chemical compounds in clinical, toxicological, and environmental samples. Laboratories also use mass spectrometry to analyze the structure of a compound by breaking down the compound into its components and measuring their mass and intensity. Those data for a given compound are its mass spectrum.
Using high resolution mass spectrometry is an emerging practice in laboratory analysis that determines a compound’s mass spectrum to a higher degree of accuracy and precision. The collection of those data for an array of compounds can be organized into a high-resolution mass spectral library. This resource can provide reference data to increase confidence in compound identification when commercial standard reference material is unavailable.
The high-resolution mass spectral libraries for opioid analysis available below include data that enable identification of all the 200+ opioids and opioid-related compounds also covered by the TOM Kits® product line.
Multiple library formats are provided below for use on Agilent, Sciex, or Thermo mass spectrometry platforms. The NIST library format, created from data collected on an Agilent QTOF for the FAS Kit and on a Thermo Exploris 480 for the EDP Kit, enables this library to be used on these and other instrument platforms.
Available Libraries and Specifications
, TRACEABLE OPIOID MATERIAL®, and TOM Kits® are registered marks of HHS.
Disclaimer
Use of trade names and commercial sources is for identification only and does not constitute endorsement by the U.S. Department of Health and Human Services or the U.S. Centers for Disease Control and Prevention.
These libraries are a collection of product ion spectra and do not eliminate the need to meet analytical method requirements of other federal agencies.