At a glance
Table 11 from the Guideline for Disinfection and Sterilization in Healthcare Facilities (2008).
Comparative evaluation of the microbicidal activity of low-temperature sterilization technology of carriers sterilized by various low-temperature sterilization technologies (based on tests of inoculated carriers in lab setting)
| Challenge | Ethylene Oxide 12/88 | 100% Ethylene Oxide | HCFC – Ethylene Oxide | Hydrogen Peroxide Gas Plasma 100 | Hydrogen Peroxide Gas Plasma 100S | Peracetic Acid | Reference |
|---|---|---|---|---|---|---|---|
| No salt or serum1 | 100% | 100% | 96% | 100% | No Data | No Data | Alfa 721 |
| 10% serum and 0.65% salt2 | 97% | 60% | 95% | 37% | No Data | No Data | Alfa 721 |
| Lumen (125 cm long × 3 mm wide) without serum or salt1 | No Data | 96% | 96% | No Data | No Data | No Data | Alfa 721 |
| Lumen (125 cm long × 3 mm wide) with 10% serum and 0.65% salt2 | 44% | 40% | 49% | 35% | No Data | 100%1 | Alfa 721 |
| Lumen (40 cm long × 3 mm wide)3 | ND | ND | 100% | 95% | 100% | 8% | Rutala 856 |
| Lumen (40 cm long × 2 mm wide)3 | ND | ND | 100% | 93% | 100% | No Data | Rutala 856 |
| Lumen (40 cm long × 1 mm wide)3 | ND | ND | 100% | 26% | 100% | No Data | Rutala 856 |
| Lumen (40 cm long × 3 mm wide)4 | ND | ND | 100% | 100% | 100% | No Data | Rutala 856 |
Modified from Rutala. 825
HCFC hydrochlorofluorocarbon
1 Test organisms included Enterococcus faecalis, Mycobacterium chelonae, and Bacillus atrophaeus spores.
2 Test organisms included E. faecalis, P. aeruginosa, E. coli, M. chelonae, B. atrophaeus spores, G. stearothermophilusspores, and B. circulans spores.
3 Test organism was G. stearothermophilus spores. The lumen test units had a removable 5 cm center piece (1.2 cm diameter) of stainless steel sealed to the narrower steel tubing by hard rubber septums.
4 Test organism was G. stearothermophilus spores. The lumen test unit was a straight stainless steel tube.
- Updates
- Authors
- Summary of Recommendations
- Introduction
- Rational Approach
- Healthcare Equipment
- Efficacy Factors
- Cleaning
- Disinfection
- Chemical Disinfectants
- Miscellaneous Inactivating Agents
- Regulatory Framework
- Neutralization of Germicides
- Sterilization
- Steam Sterilization
- Flash Sterilization
- Low-Temperature Sterilization
- Ethylene Oxide "Gas" Sterilization
- Hydrogen Peroxide Gas Plasma
- Peracetic Acid Sterilization
- Microbicidal Activity of Low-Temperature Sterilization
- Bioburden of Surgical Devices
- Cleaning Effect on Sterilization
- Other Sterilization Methods
- Sterilizing Practices
- Reuse of Single-Use Medical Devices
- Conclusion
- Performance Indicators
- Glossary
- References
- Executive Summary
- Tables and Figure
- Sterilization and Disinfection Methods
- Properties of an ideal disinfectant
- Epidemiologic Evidence
- Resistance of Microorganisms
- Comparison of Selected Chemicals
- Chemical Advantages and Disadvantages
- Sterilization Advantages & Disadvantages
- Minimum Steam Sterilization Cycle Times
- Flash Steam Sterilization Parameters
- Ideal Low-Temperature Sterilization
- Sterilization Efficacy
- Evaluation of Microbicidal Activity
- Positive Biological Indicator