About Global HPV Vaccination

Key points

  • Human papillomavirus (HPV) is a vaccine-preventable infection that can lead to cervical cancer and other cancers
  • Cervical cancer claims the lives of more than 340,000 women globally each year and is the 4th most common cancer among women worldwide
  • Increasing HPV vaccine coverage in girls will prevent more deaths per person vaccinated than any other immunization activity, according to estimates

Why it's an issue

Human Papillomavirus (HPV) is an infection that can lead to cervical cancer. This common female cancer claims the lives of more than 340,000 women worldwide every year.

A healthcare worker vaccinating a girl.
A nurse vaccinates a girl in Peru against HPV. ©UNICEF/U.S.CDC/UN0724532/Goupil.

CDC works with partners to help protect those most at risk from cervical cancer. Vaccination at ages 9-14 is an effective way to prevent HPV infection, cervical cancer, and other HPV-related cancers.

Facts

About 90% of cervical cancer cases and deaths occur in low- and middle-income countries.‎

In 2020, about 90% of new cases and deaths from cervical cancer occurred in low- and middle-income countries with limited access to HPV vaccination, preventative screenings, and treatment.

More than 25% (51 out of 194) of the world's countries do not include HPV vaccination in their national immunization programs. do not include HPV vaccination in their national immunization programs.

Prevention

HPV vaccination is a cost-effective and feasible public health intervention that saves lives.‎

It is estimated that increasing HPV coverage in girls will avert more deaths per person vaccinated than any other immunization activity.


The Cervical Cancer Elimination Initiative calls for vaccinating 90% of girls worldwide by age 15, as well as setting targets for screening and treatment.

In addition to preventing cervical cancer, the HPV vaccine has other benefits, including preventing genital warts and other forms of cancer caused by HPV.

What CDC is doing

Without changes to prevention and control, annual cervical cancer deaths may rise to over 400,000 by the year 2030. CDC works with partners to increase HPV vaccination coverage to protect women around the world from cervical cancer.

CDC supports:

  • Developing evidence-based HPV vaccination policy and guidelines
  • Sharing best practices, such as multi-country, peer-to-peer HPV learning workshops
  • Equipping country programs and decision-making bodies with information on HPV program sustainability, feasibility, impact, and cost
  • Conducting operational HPV research and improving understanding among key stakeholders
  • Evaluating HPV programs, like the national HPV vaccination programs in Zimbabwe, Senegal, and Tanzania