Toxicological Outbreak Investigation Course and Toolkit

At a glance

The goal of the Toxicological Outbreak Investigation Course is to provide information, resources, and learning activities to impart the knowledge and skills needed to investigate a toxicological outbreak.

Three nuclear reactors with the CDC logo and text that says "Toxicological Outbreak Investigation."

Toxicological Outbreak Investigation online training

Module 1. Course introduction and overview

In this module, we will:

  • Define what a toxic agent is
  • Provide a brief overview of the course
  • Describe the contents of the Toxicological Outbreak Investigation Toolkit

Launch Module 1 or download Module 1 slides.

Module 2. Toxicological principles

In this module, we will:

  • Consider what a toxic agent outbreak looks like and the characteristics to look for when determining whether one is taking place
  • Define toxidromes
  • Discuss the various factors that affect toxicity
  • Examine two key concepts used by toxicologists

Launch Module 2 or download Module 2 slides

Module 3. Toxicological laboratory principles

In this module, we will:

  • Explain the importance of early sample collection
  • Discuss laboratory testing considerations
  • Identify information needed in sample collection protocols
  • Discuss the collection of comparison samples

Launch Module 3 or download Module 3 slides

Module 4. Analyzing and interpreting laboratory results

In this module, we will:

  • Discuss how to analyze and interpret laboratory results
  • Define "limit of detection" (LOD)
  • Identify constant values that can be substituted for values lower than the LOD
  • Provide examples of how adjustments may be made to laboratory results
  • Discuss log-normal distribution data
  • Describe information needed to interpret laboratory results

Launch Module 4 or download Module 4 slides

Module 5. Steps of a toxicological outbreak investigation

This module includes the steps in an outbreak investigation.

Launch Module 5 Part 1, Part 2, and Part 3 or download Module 5 slides

Module 6. Domestic case study

In this module, you will practice what you have learned in Modules 1-5 by completing a domestic case study.

Launch Module 6 or download Module 6 slides

Module 7. International case study

In this module, you will practice what you have learned in Modules 1-5 by completing an international case study.

Launch Module 7 or download Module 7 slides.

Toxicological Outbreak Investigation Toolkit

The Toxicological Outbreak Investigation Toolkit is a collection of sample customizable documents that can be used during an outbreak investigation, including:

  • Qualitative epidemiological questions
  • Sample line list
  • Sample log
  • Sample medical record abstraction form
  • Sample questionnaire
  • Toxidrome chart

Download the toolkit.