National Diabetes Statistics Report

• Total: 38.4 million people have diabetes (11.6% of the U.S. population)
• Diagnosed: 29.7 million people, including 29.4 million adults
• Undiagnosed: 8.7 million people (22.8% of adults with diabetes are undiagnosed)

• Total: 97.6 million people aged 18 years or older have prediabetes (38.0% of the adult U.S. population)
• 65 years or older: 27.2 million people aged 65 years or older (48.8%) have prediabetes

• During 2001–2020, the age-adjusted prevalence of total diabetes significantly increased among adults aged 18 years or older (Figure 1).
• Prevalence estimates for total diabetes were 10.3% in 2001–2004 and 13.2% in 2017–2020 (Appendix Table 2).
• During this period, the age-adjusted prevalence significantly increased for diagnosed diabetes. No significant change in undiagnosed diabetes prevalence was found (Figure 1; Appendix Table 2).

Figure 1. Trends in age-adjusted prevalence of diagnosed diabetes, undiagnosed diabetes, and total diabetes among adults aged 18 years or older, United States, 2001–2020

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Notes: Diagnosed diabetes was based on self-report. Undiagnosed diabetes was based on fasting plasma glucose and A1C levels among people self-reporting no diabetes. Time period 2017–2020 covers January 2017 through March 2020 only.

Among U.S. adults aged 20 years or older, age-adjusted, county-level data indicated:

• In 2021, estimates of diagnosed diabetes prevalence varied across U.S. counties, ranging from 4.4% to 17.9% (Figure 3).
• Median county-level prevalence of diagnosed diabetes increased from 6.3% in 2004 to 8.3% in 2021.

Figure 3. Age-adjusted, county-level prevalence of diagnosed diabetes among adults aged 20 years or older, United States, 2004 and 2021

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Among U.S. adults aged 18 years or older, crude estimates for 2021 were:

• 1.2 million new cases of diabetes—or 5.9 per 1,000 people—were diagnosed (Table 3).
• Compared to adults aged 18 to 44 years, incidence rates of diagnosed diabetes were higher among adults aged 45 to 64 years and those aged 65 years and older (Table 3).

Among U.S. adults aged 18 years or older, age-adjusted data for 2019–2021 indicated:

• Compared to non-Hispanic White adults and Asian adults, incidence estimates were higher for non-Hispanic Black adults and Hispanic adults (Appendix Table 4).
• Incidence rates of diagnosed diabetes were higher among those with less than high school education and those with high school education only compared to adults with more than high school education (Appendix Table 4).
• Incidence was similar among adults living in metropolitan and nonmetropolitan areas (Appendix Table 4).

Table 3. Estimated crude incidence of diagnosed diabetes among adults aged 18 years or older, United States, 2019–2021

CI = confidence interval.

^a Population estimates for 2021 were derived from rates for 2019–2021 applied to July 1, 2021 U.S. resident population estimates from the U.S. Census Bureau (See Appendix B: Detailed Methods).

^b Rates were calculated using 2021 data only.

Data sources: 2019–2021 National Health Interview Survey and 2021 U.S. Census Bureau data.

• Among adults aged 18 years or older, the age-adjusted incidence of diagnosed diabetes was similar in 2000 (6.2 per 1,000 adults) and 2021 (5.8 per 1,000 adults). A significant decreasing trend in incidence was detected after 2008 (8.4 per 1,000 adults) through 2021. (Figure 4).

Figure 4. Trends in age-adjusted incidence of diagnosed diabetes among adults aged 18 years or older, United States, 2000–2021

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Notes: Data shown are estimated incidence rates (solid blue line) and 95% confidence intervals (shaded). Joinpoint identified in 2008 (see Appendix B: Detailed Methods and Data Sources). Because of changes to the survey design and survey instruments after 2018, comparisons of the 2000–2018 and 2019–2021 data should be examined with caution.

Among US adults aged 20 years or older, age-adjusted, county-level data indicated:

• Estimates of diagnosed diabetes incidence varied across U.S. counties, ranging from 2.2 to 53.5 per 1,000 people in 2020 (for more detail, see U.S. Diabetes Surveillance System).
• Median county-level incidence of diagnosed diabetes was 9.7 and 9.0 per 1,000 people in 2004 and 2020, respectively (for more detail, see U.S. Diabetes Surveillance System).

Data from the SEARCH for Diabetes in Youth study indicated that, during 2017–2018, the estimated annual number of newly diagnosed cases in the United States included:

• 18,169 children and adolescents younger than age 20 years with type 1 diabetes.
• 5,293 children and adolescents aged 10 to 19 years with type 2 diabetes.

Among U.S. children and adolescents aged younger than 20 years, modeled data in Figure 5 showed:

• For the period 2002–2018, overall incidence of type 1 diabetes significantly increased.
• Non-Hispanic Asian or Pacific Islander children and adolescents had the largest significant increases in incidence of type 1 diabetes, followed by Hispanic and non-Hispanic Black children and adolescents.
• Non-Hispanic White children and adolescents had the highest incidence of type 1 diabetes across all years.

Among U.S. children and adolescents aged 10 to 19 years, modeled data in Figure 5 showed:

• For the entire period 2002–2018, overall incidence of type 2 diabetes significantly increased.
• Incidence of type 2 diabetes significantly increased for all racial and ethnic groups, especially Asian or Pacific Islander, Hispanic, and non-Hispanic Black children and adolescents.
• Non-Hispanic Black children and adolescents had the highest incidence of type 2 diabetes across all years.

Figure 5. Trends in incidence of type 1 and type 2 diabetes in children and adolescents, overall and by race and ethnicity, 2002–2018

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Note: Adapted from Wagenknecht LE et al1. Data are model-adjusted incidence estimates (see Appendix B: Detailed Methods and Data Sources).

• There were no significant changes in age-adjusted prevalence of prediabetes from 2005–2008 to 2017–2020 (Appendix Table 7). About one-third of U.S. adults had prediabetes over the entire period.
• Among adults with prediabetes, the age-adjusted percentage aware that they had this condition increased from 6.5% in 2005–2008 to 17.4% in 2017–2020 (Appendix Table 7).

• 22.1% were tobacco users based on self-report or levels of serum cotinine.
• 14.6% reported current cigarette smoking.
• 36.0% had quit smoking but had a history of smoking at least 100 cigarettes in their lifetime.

• 89.8% were overweight or had obesity, defined as a body mass index (BMI) of 25 kg/m² or higher. Specifically
  • 26.9% were overweight (BMI of 25.0 to 29.9 kg/m²).
  • 47.1% had obesity (BMI of 30.0 to 39.9 kg/m²).
  • 15.7% had extreme obesity (BMI of 40.0 kg/m² or higher).

• 31.9% were physically inactive, defined as getting less than 10 minutes a week of moderate or vigorous activity in each physical activity category of work, leisure time, and transportation.

• 47.4% had an A1C value of 7.0% or higher. Specifically:
  • 22.9% had an A1C value of 7.0% to 7.9%.
  • 11.5% had an A1C value of 8.0% to 9.0%.
  • 13.0% had an A1C value higher than 9.0%.
• 10.4% of adults aged 18–44 years had A1C levels of 10% or higher, compared to 9.4% of those aged 45–64 years and 2.6% of those aged 65 years or older (Appendix Table 9).

• 80.6% had a systolic blood pressure of 130 mmHg or higher or diastolic blood pressure of 80 mmHg or higher or were on prescription medication for their high blood pressure (Appendix Table 8).
• 70.8% had a systolic blood pressure of 140 mmHg or higher or diastolic blood pressure of 90 mmHg or higher or were on prescription medication for their high blood pressure (Appendix Table 8).

• 39.5% had a non-HDL level of 130 mg/dL or higher. Specifically:
  • 19.9% had a non-HDL level of 130 to 159 mg/dL.
  • 11.5% had a non-HDL level of 160 to 189 mg/dL.
  • 8.0% had a non-HDL level of 190 mg/dL or higher.

* Non-high-density lipoprotein cholesterol (non-HDL) contains all the atherogenic lipoproteins, including low-density lipoprotein cholesterol (LDL), very-low-density lipoprotein, lipoprotein(a), and others. Growing evidence supports non-HDL as a better predictor of cardiovascular disease risk than LDL2.

• 78.8% reported having at least one usual source of diabetes care, such as a doctor or other health care professional.

• 24.1% met the recommended goal of at least 150 minutes per week of leisure-time physical activity.

• 73.1% reported managing or losing weight to lower their risk for developing certain diseases.

• 57.8% of adults aged 40–75 years were on statin therapy.

• 11.1% met all these criteria: A1C value <7.0%, blood pressure <130/80 mmHg, non-HDL cholesterol <130 mg/dL, and being a nonsmoker (Table 5).
• 36.8% met all these criteria: A1C value <8.0%, blood pressure <140/90 mmHg, non-HDL cholesterol <160 mg/dL, and being a nonsmoker (Table 5).

Table 5. Crude percentage of adults aged 18 years or older with diagnosed diabetes meeting all ABCs goals, United States, 2017–202034

Notes: ABCs = A1C, blood pressure, cholesterol, and smoking. CI = confidence interval. Estimates are crude percentages and 95% confidence intervals.

Data source: 2017–2020 National Health and Nutrition Examination Survey.

Among U.S. adults aged 18 years or older with diagnosed diabetes, crude data for 2021 indicated:

• 87.9% (95% CI, 86.4–89.3) received all three recommended ABC tests by a health professional in the past year.
  • 94.2% (95% CI, 93.0–95.2) received a blood test for A1C.
  • 96.8% (95% CI, 95.8–97.5) had their blood pressure checked.
  • 93.0% (95% CI, 91.8–94.1) had their cholesterol checked.

Among U.S. adults aged 18 years or older with diagnosed diabetes, crude data for 2021 indicated:

• 65.9% (95% CI, 63.8–68.0) had received an influenza vaccination in the past year.
• 81.5% (95% CI, 79.4–83.4) had ever received a COVID-19 vaccination.
  • 8.9% (95% CI, 7.6–10.4) had received one COVID-19 vaccination.
  • 63.8% (95% CI, 61.5–66.1) had received two COVID-19 vaccinations.
  • 8.7% (95% CI, 7.6–10.1) had received more than two COVID-19 vaccinations.
• 26.2% (95% CI, 24.2–28.3) had ever received a hepatitis B vaccination.
  • 35.9% (95% CI, 32.2–39.8) of adults aged 18–59 years had ever received a hepatitis B vaccination.
• 50.7% (95% CI, 48.6–52.9) had ever received a pneumococcal vaccination.

In 2020, about 16.8 million emergency department visits were reported with diabetes as any listed diagnosis among adults aged 18 years or older (Table 6), including:

• 267,000 for hyperglycemic crisis (11.4 per 1,000 adults with diabetes).
• 202,000 for hypoglycemia (8.6 per 1,000 adults with diabetes).

Table 6. Number and rate of emergency department visits per 1,000 adults aged 18 years or older with diabetes for selected causes, United States, 2019 and 2020

Note: CI = confidence interval. Numbers rounded to the nearest thousand. Data sources: 2019 and 2020 National Emergency Department Sample; 2019 and 2020 National Health Interview Survey.

In 2020, of the emergency department visits with diabetes as any listed diagnosis among U.S. adults aged 18 years or older, disposition data (see Appendix B: Detailed Methods and Data Sources) indicated:

• 54.9% were treated and released; 38.4% were admitted to the hospital; 2.5% were transferred to another hospital; 2.6% were transferred to a skilled nursing facility, an intermediate care facility, or home with home health care; 1.3% left against medical advice; 0.3% died; and <0.1% had unknown disposition but were not admitted to a hospital.
• Of those ED visits involving hypoglycemia, 66.8% were treated and released, 25.1% were admitted to the hospital, and <0.1% died.
• Of the ED visits involving hyperglycemic crisis, 8.4% were treated and released, 84.4% were admitted to the hospital, and <0.1% died.

In 2020, a total of 7.86 million hospital discharges were reported with diabetes as any listed diagnosis among U.S. adults aged 18 years or older (335.4 per 1,000 adults with diabetes) (Table 7). These discharges included:

• 1.68 million for major cardiovascular diseases (71.6 per 1,000 adults with diabetes), including:
  • 368,000 for ischemic heart disease (15.7 per 1,000 adults with diabetes).
  • 321,000 for stroke (13.7 per 1,000 adults with diabetes).
• 160,000 for a lower-extremity amputation (6.8 per 1,000 adults with diabetes).
• 232,000 for hyperglycemic crisis (9.9 per 1,000 adults with diabetes).
• 51,000 for hypoglycemia (2.2 per 1,000 adults with diabetes).

Table 7. Number and rate of hospitalizations per 1,000 adults aged 18 years or older with diabetes for selected causes, United States, 2019 and 2020

Notes: CI = confidence interval. Numbers rounded to the nearest thousand. Data sources: 2019 and 2020 National Inpatient Sample; 2019 and 2020 National Health Interview Survey.

Among U.S. adults aged 18 years or older with diagnosed diabetes, crude data for 2017–2020 shown in Appendix Table 11 indicated:

• 39.2% had chronic kidney disease (CKD, stages 1–4), based on the updated 2021 CKD Epidemiology Collaboration (CKD-EPI) equation for estimated glomerular filtration rate (eGFR).
  • 15.7% had moderate to severe CKD (stage 3 or 4).
  • 23.1% of non-Hispanic Black adults, 17.2% of non-Hispanic White adults, and 8.9% of Hispanic adults had moderate to severe CKD (stage 3 or 4).
  • 32.5% with moderate to severe CKD (stage 3 or 4) were aware of their kidney disease.
• 40.9% had chronic kidney disease (CKD, stages 1–4), based on the 2009 CKD-EPI eGFR equation, which included a factor for non-Hispanic Black race.

In 2019:

• A total of 61,522 people developed end-stage kidney disease with diabetes as the primary cause.
• Crude incidence of end-stage kidney disease with diabetes as the primary cause was 192.7 per 1 million population (61,522 new cases). Adjusted for age group, sex, and racial or ethnic group, the rate was 179.5 per 1 million people.
• The proportion of end-stage kidney disease with diabetes listed as the primary cause was 39.2% (307,385 out of 783,594 people). As a result, diabetes was the leading cause of end-stage kidney disease, followed by high blood pressure (26.7%), glomerulonephritis (14.6%), and cystic kidney disease (5.0%).

• Diabetes is the leading cause of new cases of blindness among adults aged 18–64 years.
• Among US adults aged 18 years or older with diagnosed diabetes, crude data for 2021 indicated:
  • 10.1% (95% CI, 9.6%–11.3%) reported severe vision difficulty or blindness.

• In 2021, diabetes was the eighth leading cause of death in the United States. This finding is based on 103,294 death certificates in which diabetes was listed as the underlying cause of death (crude rate, 31.1 per 100,000 people).
• In 2021, there were 399,401 death certificates with diabetes listed as the underlying or contributing cause of death (crude rate, 120.3 per 100,000 people).

• The total direct and indirect estimated costs* of diagnosed diabetes in the United States in 2022 was $413 billion.
• Total direct estimated costs of diagnosed diabetes increased from $227 billion in 2012 to $307 billion in 2022 (2022 dollars). Total indirect costs increased from $89 billion to $106 billion in the same period (2022 dollars).
• From 2012 to 2022, excess medical costs per person associated with diabetes increased from $10,179 to $12,022 (2022 dollars).

* Direct costs = medical costs; indirect costs = lost productivity from work-related absenteeism, reduced productivity at work and at home, unemployment from chronic disability, and premature mortality.