Psychosocial Pathways
Indicator Profile
Psychosocial pathways are the ways in which social, cultural, and environmental factors influence an individual’s mind and behavior.1,2 This concept focuses on the intersection and interaction of individual-level factors such as mental well-being and stress, with social factors such as social networks and support systems.
Psychosocial factors, such as occupational stress, social support or isolation, sleep quality, and mental health, are shaped by racial, economic, and other societal structures. For example, unemployment and loss of income may lead to increased stress and feelings of worthlessness, which then affect health through lifestyle or behavioral changes (e.g., less healthy eating, increased drinking or smoking) or through neurological changes. Psychosocial pathways refer to both the indirect influence of psychosocial factors on health through behavior modifications and the direct impact on health via psychoneuroendocrine changes.3
Indicators
This document provides guidance for measuring seven indicators related to psychosocial pathways that influence risk for developing or the ability to manage cardiovascular disease (CVD). The seven psychosocial pathway indicators are measured at different levels of analysis, including individual, census tract, county, and state.
Access to Mental Health Care
Why is this indicator relevant?
Health care access is a public health issue, because many Americans lack the physical or financial resources to receive the health care services they need. Mental health care access is challenging due to the scarcity of mental health services and the social stigma associated with mental health.4 One indicator of mental health care access is the extent to which mental health care is available in a geographic area.
In the United States, more than half of Americans are diagnosed with a mental illness or disorder during their lifetime, yet nearly 30% of the population live in a county designated as a Mental Health Professional Shortage Area (MHPSA).5,6 MHPSAs are areas where the ratio of mental health providers (e.g., psychiatrists, clinical social workers, therapists) to residents is 1 to 30,000 or less.7 A National Violent Death Reporting System study between 2005 and 2010 (n = 57,877 suicides) compared adult decedents who received any or no mental health treatment within 2 months before death. Results suggest that having access to mental health services improves diagnosis and may prevent deaths by suicide.8 Low availability of mental health services at the county level is also linked to negative health outcomes. Mental health shortage areas have higher county-level suicide rates, and individuals with serious mental illnesses living in shortage areas are more likely to be admitted to the hospital.9,10
Mental disorders play a role in multiple aspects of the pathogenesis of CVD and other chronic noncommunicable diseases. They independently confer an adverse prognosis for CVD mortality and death from all causes and directly impair quality of life.11
This indicator can be assessed by the following measure. Click on the measure to learn more:
Adverse Childhood Experiences (ACEs)
Why is this indicator relevant?
Research over the past decade has pointed to the cumulative and long-lasting impact of childhood experiences and early life factors on adult health status. ACEs refer to traumatic events and severe or chronic stress occurring during childhood (ages 0–17), including abuse (physical, emotional, and sexual), neglect (emotional and physical), and household dysfunction (parental mental health illnesses, household substance abuse, violence between parents or caregivers, incarcerated family member, and parental separation or divorce).12 Exposure to stressful and traumatic events during childhood disrupts normal psychosocial development and may lead to the development of mental health disorders and negative coping strategies such as smoking, overeating, and physical inactivity, all of which are risk factors for CVD.13,14 Moreover, prolonged stress in childhood alters biological functioning in stress regulatory pathways, leading to negative stress responsivity in adulthood.15
Low social economic status, early life stress, and ACEs are linked to the development of poor health behaviors, hypertension, and increased risk for ischemic heart disease and CVD.16,17,18,19 A seminal CDC-Kaiser Permanente study on ACEs found a strong dose–response relationship between childhood exposure to abuse, neglect, and dysfunction and multiple risk factors for several of the leading causes of death, including alcoholism, smoking, drug abuse, severe obesity, and physical inactivity.20 The study also found a graded relationship between ACEs and conditions such as ischemic heart disease, cancer, chronic lung disease, and liver disease.21
The life course perspective has been increasingly incorporated into cardiovascular health strategies. In a scientific advisory, the American Heart Association stated that “cardiovascular health is being lost from childhood through young adulthood” and declared that “we must improve the distribution of cardiovascular health levels across the population by preserving cardiovascular health from childhood and by treating health risk behaviors to help more individuals improve their cardiovascular health into older ages.”22
Adverse childhood experiences (ACEs) are traumatic events and severe or chronic stress that occur during childhood (ages 0–17), including abuse (physical, emotional, and sexual), neglect (emotional and physical), and household dysfunction (parental mental health illnesses, household substance abuse, violence between parents or caregivers, incarcerated family member, and parental separation or divorce). This indicator can be assessed by the following measure. Click on the measure to learn more:
Mental Health Disorders
Why is this indicator relevant?
Mental health refers to emotional, psychological, and social well-being; mental health disorders refers to conditions affecting cognition, emotion, and behavior (e.g., schizophrenia, depression, autism).25
Certain racial/ethnic groups, women, and individuals who identify as lesbian, gay, bisexual, transgender, queer, intersex, asexual, or other sexual orientations (LGBTQIA+) are disproportionately affected by mental health issues due to greater exposure to several risk factors, including lack of access to mental health care services, discrimination, poverty, and unemployment. Although the prevalence of clinical depression is lower among Black/African American persons (24.6%) and Hispanic/Latino persons (19.6%) than among White persons (34.7%), depression is more likely to be persistent and debilitating in these groups.26,27 Furthermore, these differences are partially due to Black/African American and Hispanic/Latino American persons being less likely to seek clinical help, and providers being less likely to identify and diagnose culturally different presentations of mental health disorders. Therefore, it is speculated that clinical prevalence of depression is underestimated for these groups and the true depression prevalence is higher for Black/African American and Hispanic/Latino persons than for White persons.28 Moreover, people who identify as multiracial are most likely to report mental illness within the past year compared with other racial/ethnic groups. American Indians/Alaskan Native persons report higher prevalence of post-traumatic stress disorder (PTSD) and substance use disorders than any other group.29 LGBTQIA+ youth are four times more likely to attempt suicide than their heterosexual/cisgender counterparts.30
Mental health and cardiovascular health have a well-established relationship. Specifically, studies show that depression, anxiety, and PTSD are associated with negative CVD outcomes.31 Patients with CVD are three times more likely to be depressed than those without CVD. The American Heart Association recommends that depression be recognized as a major risk factor for heart disease and heart disease mortality. Despite this, many patients are rarely assessed for mental health problems, and mental health disorders are often undiagnosed.32
Mental health refers to emotional, psychological, and social well-being; mental health disorders refer to conditions affecting cognition, emotion, and behavior (e.g., schizophrenia, depression, autism). This indicator can be assessed by the following measures. Click on each measure to learn more:
Sleep Health
Why is this indicator relevant?
Sleep health is commonly recognized as comprising several measurable dimensions, including sleep duration (total amount of sleep per 24-hour day), sleep continuity or efficiency (ease of falling asleep and returning to sleep), timing (placement of sleep within the 24-hour day), alertness/sleepiness (ability to maintain attentive wakefulness), and satisfaction/quality (subjective assessment of “good” or “poor” sleep).37 These dimensions are associated with physical, mental, and neurobehavioral well-being. Moreover, sleep is an important modulator of cardiovascular health; sleep deprivation is linked to hypertension, congestive heart failure, and stroke.38,39
Historically, sleep duration in the United States has declined steadily from the 1960s onward, plateauing in the early 21st century to an average of 6 hours, which is below CDC’s and National Sleep Foundation’s minimum recommendation of at least 7 hours per day. Certain racial/ethnic groups, including Black/African American persons, multiracial persons, Native Hawaiian persons, Pacific Islander persons, American Indians/Alaska Native persons, and immigrant groups have worse sleep outcomes, averaging less sleep and lower quality of sleep than their White person counterparts.40,41 For instance, the CDC Behavioral Risk Factor Surveillance System (BRFSS) found that 46.3% of Native Hawaiian and Pacific Islander persons, 45.8% of Black/African American persons, 44.3% of multiracial persons, and 40.4% of American Indians/Alaska Native persons reported getting less than 7 hours of sleep per day, compared with 33.4% of White persons.42 Other studies found significantly less slow-wave sleep and more self-reported daytime fatigue among Black/African American persons compared to White persons.43 Hypothesized contributors to racial/ethnic sleep inequities include competing demands (e.g., occupational and financial considerations), environmental exposures (e.g., air pollution), and psychosocial stressors (e.g., perceived discrimination and acculturation).44,45
Current sleep research studies have an increased focus on investigating the relationship between sleep and other disparities certain groups experience. Many researchers consider sleep health indicators, including sleep duration, sleep-disordered breathing, and insomnia, as prominent contributing factors to CVD outcome disparities.46 Increasing awareness of sleep-mediated causes of disease risk, funding for research into underlying sleep disparity causes, and public education on the importance of sleep health, may lead to cardiovascular and overall health improvements.
Sleep health is commonly recognized as comprising several measurable dimensions, including sleep duration (total amount of sleep per 24-hour day), sleep continuity or efficiency (ease of falling asleep and returning to sleep), timing (placement of sleep within the 24-hour day), alertness/sleepiness (ability to maintain attentive wakefulness), and satisfaction/quality (subjective assessment of “good” or “poor” sleep). This indicator can be assessed by the following measure. Click on the measure to learn more:
Social Support
Why is this indicator relevant?
Social support refers to the benefits provided through relationships with family members, friends, spouses, colleagues, and acquaintances (e.g., emotional, instrumental, and informational support). Social support and social integration are predictive of mortality for a number of conditions, including CVD.48,49,50,51,52 Lack of social support and poor social integration are linked to increased inflammation, which is a risk factor for CVD.53,54 Social support also buffers the negative effects of discrimination on health outcomes. Specifically, social support mitigates the adverse health consequences of discrimination. Researchers posit that emotionally supportive environments allow people to better cope with unfair treatment.55 For instance, a study in California showed that Hispanic/Latino immigrants who reported discriminatory experiences and low social support were more likely to report poor health than those who reported discriminatory experiences and high levels of social support.56 Another study found that peer support interventions that community health workers delivered, including barbershop and beauty parlor interventions, were associated with decreases in CVD risk factors.57 Other studies, however, found no association between social support and CVD outcomes overall, or detected effects in only one gender after adjusting for age and other characteristics.58,59,60,61 Therefore, further research is warranted to elucidate the effect of social support on CVD risk and whether it may serve as a buffer for the negative health consequences of discrimination.
Social support refers to the benefits provided through relationships with family members, friends, spouses, colleagues, and acquaintances (e.g., emotional, instrumental, and informational support). This indicator can be assessed by the following measure. Click on the measure to learn more:
Stigma
Why is this indicator relevant?
Social stigmatization is the experience of being discredited or rejected due to a characteristic or attribute that is considered undesirable and can lead to prejudice, stereotyping, and/or discrimination.65 Stigma-consciousness refers to the extent to which a person anticipates discrimination or prejudice.66 Chronic exposure to stigma and chronic self-consciousness of stigmatized status may affect CVD risk by negatively affecting physiological response to stress and increasing the risk of physiological dysregulation.65,67
The experience of stigma and the anticipatory vigilance of stigma-consciousness are social stressors that may result in heightened acute or chronic stress. Acute stress can cause increased heart rate, blood pressure, and secretion of stress hormones.68 Chronic stress can cause constantly elevated heart rate and blood pressure and vasoconstriction, which may lead to higher likelihood of developing myocardial ischemia, atherosclerosis, and thrombosis.69 Several attributes of stigma, including race, weight, gender, and sexual orientation, are associated with negative cardiovascular risk factors and health outcomes.70 One study found that weight-related stigma and perceived discrimination was associated with a two-fold risk of high allostatic load.71 Another study found that racial discrimination and stigma-consciousness was associated with higher blood pressure and hypertension in Black/African American and Hispanic/Latino men.72
Social stigmatization is the experience of being discredited or rejected due to a characteristic or attribute that is considered undesirable and can lead to prejudice, stereotyping, and/or discrimination. This indicator can be assessed by the following measure. Click on the measure to learn more:
Stress
Why is this indicator relevant?
Stress is the physiological or psychological response to internal or external stressors.76 Perceived stress, or how an individual experiences stress, may include stressors experienced throughout the life course, including during childhood, adolescence, and adulthood.77,78,79 Although experiencing stress can be normal and some stress can be a motivating factor, chronic stress, or stress that remains constant and persists over an extended period, can be debilitating and overwhelming, affecting an individual’s physical and psychological well-being. Chronic stress can cause a variety of problems, including anxiety, insomnia, muscle pain, high blood pressure, and a weakened immune system.80 Furthermore, research shows stress contributes to “the development of major illnesses, such as heart disease, depression, and obesity.”81 Many of the indicators covered elsewhere in these profiles, such as racial/ethnic discrimination, sexism, genderism, heterosexism, unemployment, and poverty, are contributing factors to both acute and chronic stress, which have well-established connections to CVD.82,83,84,85,86
Stress management, and accompanying coping resources, offer a range of strategies to help individuals better handle stress and adversity. Coping, which is defined as cognitive and behavioral efforts made in order to manage internal or external stimuli, include task-oriented (problem solving and taking direct action to address a stressor), emotion-oriented (regulating distressing emotions), and avoidance-oriented (engaging in other activities and distancing oneself from stressor) strategies.87 By managing stress and utilizing coping resources, individuals can lead a more balanced and healthier life.88 External stress management and coping resources include general wellness programs, psychiatrists, counselors, therapists, and social workers. Community resources include connections to local businesses, community organizations, and various social networks, as well as neighborhood greenspaces and opportunities for physical activity.89,90,91
Stress is a strong predictor of CVD risk: Epidemiologic data show that chronic stress predicts coronary heart disease (CHD) occurrence.92 Positive and adaptive coping can be used as a behavioral intervention across the prevention, treatment, and rehabilitation stages of CVD. Studies show that coping strategies can reduce CVD risk, as well as manage stress and improve outcomes among CVD patients.93,94
Stress is the physiological or psychological response to internal or external stressors. Perceived stress, or how an individual experiences stress, may include stressors experienced throughout the life course, including during childhood, adolescence, and adulthood. This indicator can be assessed by the following measures. Click on each measure to learn more:
Case Example
This case example was developed from the Health Equity Indicators (HEI) Pilot Study. Seven health care organizations participated in the HEI Pilot Study from January 2022 to April 2022 to pilot-test a subset of HEIs in order to assess the feasibility of gathering and analyzing data on these indicators within health care settings. The pilot case examples document participating sites’ experiences with data collection and lessons learned from piloting the HEIs.
References
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- Dong M, Giles WH, Felitti VJ, Dube SR, Williams JE, Chapman DP, et al. Insights into causal pathways for ischemic heart disease: Adverse childhood experiences study. Circulation. 2004;110(13):1761–6. doi:10.1161/01.CIR.0000143074.54995.7F
- Su S, Jimenez MP, Roberts CT, Loucks EB. The role of adverse childhood experiences in cardiovascular disease risk: A review with emphasis on plausible mechanisms. Curr Cardiol Rep. 2015;17(10):88. doi:10.1007/s11886-015-0645-1
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- Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998;14(4):245–58. doi:10.1016/s0749-3797(98)00017-8
- Spring B, Ockene JK, Gidding SS, Mozaffarian D, Moore S, Rosal MC, et al. Better population health through behavior change in adults: A call to action. Circulation. 2013;128(19):2169–76. doi:10.1161/01.cir.0000435173.25936.e1
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