miRNA extracted from extracellular vesicles is a robust biomarker of amyotrophic lateral sclerosis
Affiliates | Sandra A. Banack [1], Rachael A. Dunlop [1], Elijah Stommel [2] ,Paul Mehta [3], Paul A. Cox [1]
[1] Brain Chemistry Labs, Jackson, WY, USA |
Journal | Journal of the Neurological Sciences |
Summary | This research paper describes a methodology of using miRNA extracted from extracellular blood vesicles as viable biomarkers to identify ALS in a population sample. Blood plasma was obtained from the National ALS Biorepository and compared with non-ALS controls. Eight miRNA biomarkers were investigated and five out of those eight were found to significantly discriminate ALS samples from the controls. The paper proposes further research and development into these eight miRNA pre-symptomatic identifying biomarkers. |
Link to paper | Read the paper here! |