Early life metal dysregulation in amyotrophic lateral sclerosis

At a glance

This study looks to determine the association of childhood metal consumption with later ALS development

Affiliates

Claudia Figueroa-Romero1, Kristen A. Mikhail1, Chris Gennings2, Paul Curtin2, Ghalib A. Bello2, Tatiana M. Botero3, Stephen A. Goutman1, Eva L. Feldman1, Manish Arora2, Christine Austin2

  1. Department of Neurology, University of Michigan
  2. Department of Environmental Medicine and Public Health, and Senator Frank Lautenberg Laboratory for Environmental Health Sciences, Icahn School of Medicine at Mount Sinai
  3. Department of Cariology, Restorative Sciences and Endodontics, School of Dentistry University of Michigan

Journal

Annals of Clinical and Translational Neurology

Summary

Deficiencies and excess of essential elements and toxic metals are implicated in amyotrophic lateral sclerosis (ALS), but the age when metal dys-regulation appears remains unknown. This study aims to determine whether metal uptake is dysregulated during childhood in individuals eventually diag-nosed with ALS.

Link to paper

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Content Source:
Agency for Toxic Substances and Disease Registry