At a glance
Affiliates
Jane A. Parkin Kullmann1, Roger Pamphlett1,2
- The Stacey Motor Neuron Disease Laboratory, Discipline of Pathology, Brain and Mind Centre, The University of Sydney
- Department of Neuropathology, Royal Prince Alfred Hospital
Summary
Exposure to toxic heavy metals, like mercury, have been suggested to be risk factors for ALS. This study investigates the link between mercury exposure and ALS. Seafood is rich in mercury. Participants were asked about their seafood consumption in an online survey. This study found no evidence of an association between mercury exposures from eating seafood with risk of developing ALS. However, an exposure to mercury toxicity in ALS patients, such as genetic or epigenetic variations, multiple toxic metal interactions, or selenium deficiency, may be present.