2022 Project: University of Wisconsin-Madison

Impact of local differences in vaccine uptake on SARS-CoV-2 evolution and spread across three Upper Midwestern states

What to know

The researchers will perform genomic surveillance in Wisconsin, Minnesota, and Michigan and analyze that data along with vaccination and demographic data. In addition, they are building and deploying systems to improve local health department integration with statewide public health data.

Decorative image with words "2022" and "SARS-CoV-2"

Findings on SARS-CoV-2 Surveillance and Investigations

Awarded in 2022, the project included the development of two models.

  • One model illustrated transmission within and between geographic subdivisions.
  • The second model was used to understand the impacts of factors such as vaccination, population density, and socioeconomic indices on viral diversity and transmission patterns.

This project is developing strategies to pivot from other sources of sampling for genomic surveillance as individual PCR tests decline. This includes novel approaches such as development of partnerships with local libraries to pilot collection of rapid antigen tests for sequencing from library patrons for community genomic surveillance. Additionally, researchers are leveraging existing partnerships with local public health department partners to incorporate research data in respiratory virus dashboards.

Awarded in 2022, this project is still in progress.