Potential Effects of a Moderate or Severe TBI

A moderate or severe TBI may result in an extended period of unconsciousness (coma) or amnesia. The effects of a moderate or severe TBI are different for each person and may change during recovery. Most people will have one or more health problems after the injury that may include:

  • Physical symptoms
  • Problems with thinking and learning, and
  • Changes in motor skills, hearing, vision, emotions/mood, or behavior1

Symptoms of moderate or severe TBI

Thinking and Learning

Thinking and Learning

Thinking and Learning

Motor Skills, Hearing, and Vision

Motor Skills, Hearing, and Vision

Motor Skills, Hearing, and Vision

Emotion/Mood

Emotion/Mood

Emotion/Mood

Behavior

Behavior

Behavior

Difficulty understanding and thinking clearly

Thinking and Learning

Difficulty understanding and thinking clearly

Weakness in arms and legs

Motor Skills, Hearing, and Vision

Weakness in arms and legs

Feeling more emotional than usual

Emotion/Mood

Feeling more emotional than usual

Trouble controlling behavior

Behavior

Trouble controlling behavior

Trouble communicating and learning skills

Thinking and Learning

Trouble communicating and learning skills

Problems with coordination and balance

Motor Skills, Hearing, and Vision

Problems with coordination and balance

Nervousness or anxiety

Emotion/Mood

Nervousness or anxiety

Personality changes

Behavior

Personality changes

Problems concentrating

Thinking and Learning

Problems concentrating

Problems with hearing and vision

Motor Skills, Hearing, and Vision

Problems with hearing and vision

Feeling more angry or aggressive than usual

Emotion/Mood

Feeling more angry or aggressive than usual

More impulsive than usual

Behavior

More impulsive than usual

Difficulty remembering information

Thinking and Learning

Difficulty remembering information

Changes in sensory perception, such as touch

Motor Skills, Hearing, and Vision

Changes in sensory perception, such as touch

Sadness, depression

Emotion/Mood

Sadness, depression

Behavior

Long-term negative effects of TBI are significant

Even after surviving a moderate or severe TBI and receiving inpatient rehabilitation services, a person’s life expectancy is 9 years shorter. TBI increases the risk of dying from several causes. Compared to people without TBI, people with TBI are more likely to die from:

Seizures 50 times, Accidental drug poisoning 11 times, Infections 9 times, and Pneumonia 6 times more likely.

After inpatient rehabilitation for TBI, the following groups are more likely to die sooner:

  • Older adults
  • Men
  • Unemployed
  • People who are not married
  • People with fewer years of education
  • People with more severe TBI
  • People with fall-related TBI

In addition, people with moderate to severe TBI typically face a variety of chronic health problems. These issues add costs and burdens to people with TBI, their families, and society. Among those still alive 5 years after injury:

  • 57% are moderately or severely disabled.
  • 55% do not have a job (but were employed at the same time of their injury)
  • 50% return to a hospital at least once
  • 33% rely on others for help with everyday activities
  • 29% are not satisfied with life
  • 29% use illicit drugs or misuse alcohol
  • 12% reside in nursing homes or other institutions
References
  1. Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. Report to Congress on traumatic brain injury in the United States: Epidemiology and rehabilitation. Atlanta (GA): Centers for Disease Control and Prevention; 2015.
  2. Corrigan JD, Cuthbert JP, Harrison-Felix C, et al. US population estimates of health and social outcomes 5 years after rehabilitation for traumatic brain injury. J Head Trauma Rehabil. 2014;29(6):E1-9.
  3. Centers for Disease Control and Prevention, National Institutes of Health. Moderate to Severe Traumatic Brain Injury is a Lifelong Condition. Available at: https://www.cdc.gov/traumaticbraininjury/pdf/Moderate_to_Severe_TBI_Lifelong-a.pdf.
  4. Goldman SM, Kamel F, Ross GW, et al. Head injury, alpha-synuclein Rep1, and Parkinson’s disease. Ann Neurol 2012;71:40–8.