Demonstration Projects

Applicants can enhance their programs by requesting funding to implement one demonstration project to expand high-impact HIV prevention and surveillance interventions and strategies. This funding will support implementation and structured evaluations of innovative programs or activities that are particularly novel or require additional resources for evaluation that would not normally be a part of implementing the required strategies and activities of the FOA. Project proposals should describe activities that are primarily focused on improving program, surveillance, and policy outcomes.  Projects that are primarily research will not be eligible. Collaborations with local partners are encouraged (e.g., universities, CBO’s, hospitals, clinics). Proposed projects must address the goals of reducing new HIV infections, improving health outcomes of PLWH, or reducing HIV-related disparities and health inequities.

Applicants may submit one proposal. The proposal must address how the applicant will implement and evaluate activities over the project period (up to four years), with more detailed information for activities conducted during the first year of funding.

Examples shown below represent possible focus areas and are used for descriptive purposes only. Additional topics that are not listed are also welcome.

Examples may include, but are not limited to:

  • Using pharmaceutical data to: 1) identify persons out of care; 2) identify strategies for re-engaging PLWH not-in-care; and 3) assess PrEP implementation for persons at risk of HIV infection.
  • Using reflex clinical decision tools to reduce undiagnosed HIV infection and identify comorbidities (e.g., reflex testing for HIV and viral hepatitis C, age-based screening, inpatient settings).
  • Implementing and evaluating innovative interventions to improve PrEP uptake and adherence in specific populations (e.g., Black and/or Latino men) or geographic areas.
  • Implementing and evaluating interventions that address social and structural factors (e.g., homelessness, mental health, poverty, unemployment, education, stigma, discrimination, patient-provider relationships, etc.) on HIV prevention and care outcomes, including HIV testing, linkage to, retention in, and re-engagement with care, treatment, and prevention among racial/ethnic and sexual minorities.
  • Using a cohort review approach for systematically reviewing health outcomes of PLWH to increase retention in care and achieve and sustain viral load suppression.
  • Using innovative methods (e.g., peer-recruitment) and molecular epidemiology to evaluate the implementation of a combination of high impact prevention interventions and strategies to limit HIV cluster growth in populations at elevated risk of infection.
  • Expanding access to medical care services through the provision of telemedicine.

Note: Proposals for a demonstration project should be included with the full application and submitted to CDC by the deadline.