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Volume 29, Number 8—August 2023
Dispatch

Emerging Corynebacterium diphtheriae Species Complex Infections, Réunion Island, France, 2015–2020

Thomas Garrigos1Comments to Author , Anais Grimal1, Edgar Badell, Nicolas Traversier, Sandrine Picot, Anne Lignereux, Mahery Ramiandrisoa, Céline Ben Cimon, Marie-Christine Jaffar-Bandjee, Houssein Gbaguidi-Haore, Julie Toubiana, Sylvain Brisse, Guillaume Miltgen2, and Olivier Belmonte2
Author affiliations: Félix Guyon University Hospital Center, Saint-Denis, Réunion Island, France (T. Garrigos, A. Grimal, N. Traversier, M.-C. Jaffar-Bandjee, G. Miltgen, O. Belmonte); Processus Infectieux en Milieu Insulaire Tropical, University of La Réunion, Inserm, CNRS, IRD, Saint-Denis, Réunion Island, France (T. Garrigos, G. Miltgen); Institut Pasteur University of Paris Cité, Paris, France (E. Badell, J. Toubiana, S. Brisse); Institut Pasteur National Reference Center for Corynebacteria of the Diphtheriae Complex, Paris (E. Badell, J. Toubiana, S. Brisse); University Hospital of La Réunion, Saint Pierre, Réunion Island, France (S. Picot); Hospital Center West Réunion, Saint Paul, Réunion Island, France (A. Lignereux); Cerballiance Laboratory, Le Port, Réunion Island, France (M. Ramiandrisoa); Inovie RéuniLAB Laboratory, Sainte-Clotilde (C. Ben Cimon); University Hospital Center and University of Bourgogne Franche-Comté, Besançon, France (H. Gbaguidi-Haore); Necker-Enfants malades Hospital, Paris (J. Toubiana).

Main Article

Table 1

Demographic and clinical features of 26 patients in study of emerging Corynebacterium diphtheriae species complex infections, Réunion Island, France, 2015–2020*

Patient no. Isolates Year Age, y/Sex Animal contact Country Travel Immunized Comorbidities/living conditions Symptoms
1
 CD1/FRC0304 2015 9/M
 None
 Mayotte, France
 No
 Yes
 Disadvantaged priority district
 Bullous pemphigoid
CD2/FRC0316
 2015
 Pneumonia
2
 CD3/FRC0314
 2015
 71/M
 None
 Mainland France
 Madagascar
 No
 Diabetic
 Left lower limb ulceration
3
 CD4/FRC0376
 2015
 13/M
 None
 Mayotte, France
 No
 Yes
 Disadvantaged district, autoimmune hepatitis
 Left lower limb ulceration
4
 CD5/FRC0383 2016 78/M
 None
 Réunion Island
Madagascar
 No
 Diabetic, heart failure, COPD
 Right lower limb ulceration
CD6/FRC0393
 2016
 Phlyctenule, right leg
5
 CD7/FRC0385
 2016
 64/M
 None
 Mainland France
 Madagascar
 No
 High blood pressure
 Left lower limb ulceration
6
 CU1/FRC0391
 2016
 67/F
 Dogs, cats
 Réunion Island
No
 Unknown
 Alcoholism, obesity, high blood pressure
 Left lower limb ulceration
7
 CD8/FRC0402
 2016
 67/M
 None
 Réunion Island
Madagascar
 Yes
 High blood pressure
 Left lower limb ulceration
8
 CD9/FRC0410
 2016
 54/M
 None
 Réunion Island
Madagascar
 Unknown
 Unspecified
 Ankle wound
9
 CD10/FRC0423
 2016
 5/F
 None
 Comoros
 No
 Yes
 Disadvantaged district
 Lower limb ulceration
10
 CD11/FRC0477
 2017
 74/M
 None
 Madagascar
 No
 Yes
 Unspecified
 Ulceration of right toe
11
 CD12/FRC0501
 2017
 66/M
 None
 Madagascar
 No
 No
 Diabetic, COPD
 Left lower limb ulceration
12
 CD13/FRC0624
 2018
 60/M
 None
 Mayotte (France)
 No
 No
 Unspecified
 Ulceration of right toe
13
 CD14/FRC0630
 2018
 68/M
 None
 Mainland France
 Madagascar
 Yes
 Diabetic, heart failure
 Wound, right tibia
14
 CD15/FRC0733
 2019
 2/M
 None
 Comoros
 No
 Yes
 Disadvantaged district
 Ulceration of right toe
15
 CD16/FRC0782 2019 38/M
 None
 Réunion Island
No
 Yes
 Homelessness, alcoholism
 Lower limb ulceration
CD17/FRC0809
 2019
16
 CD18/FRC0819
 2019
 27/M
 None
 Réunion Island
Mayotte
 No
 Alcoholism, hepatitis B
 Right ankle ulceration
17
 CU2/FRC0820
 2019
 76/M
 Dogs
 Réunion Island
No
 Unknown
 Alcoholism, diabetic
 Metatarsus damage, left foot
18
 CD19/FRC0849
 2019
 39/F
 None
 Comoros
 No
 Yes
 Lupus
 Lower limb ulceration
19
 CD20/FRC0865
 2020
 59/M
 None
 Réunion Island
No
 Unknown
 Unspecified
 Lower limb ulceration
20
 CD21/FRC0875
 2020
 55/M
 None
 Réunion Island
No
 Unknown
 Unspecified
 Left malleolar ulceration
21
 CD22/FRC0893
 2020
 17/M
 None
 Mainland France
 No
 Unknown
 Unspecified
 Foot ulceration
22
 CD23/FRC0928
 2020
 33/M
 None
 Réunion Island
No
 Unknown
 Homelessness, alcoholism
 Foot ulceration
23
 CD24/FRC0970
 2020
 59/M
 None
 Réunion Island
No
 Yes
 Homelessness, alcoholism
 Elbow abscess
24
 CD25/FRC0975
 2020
 32/M
 None
 Réunion Island
No
 Yes
 Homelessness, alcoholism
 Ulcerations of feet
25
 CD26/FRC1050
 2020
 53/M
 None
 Réunion Island
No
 Yes
 Homelessness, alcoholism
 Metatarsus damage, left foot
26 CD27/FRC1065 2020 67/M None Réunion Island No Yes High blood pressure, frontal squamous cell carcinoma Frontal sinus damage

*CD, Corynebacterium diphtheriae; COPD, chronic obstructive pulmonary disease; CU, C. ulcerans.

Main Article

1These first authors contributed equally to this article.

2These authors contributed equally to this article.

Page created: May 31, 2023
Page updated: July 25, 2023
Page reviewed: July 25, 2023
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