Volume 29, Number 11—November 2023
CME ACTIVITY - Synopsis
Group A Streptococcus Primary Peritonitis in Children, New Zealand
Amanda Taylor
, Brodie M. Elliott, John Atkinson, Sally Roberts, Lesley Voss, Emma J. Best, and Rachel Webb
, Brodie M. Elliott, John Atkinson, Sally Roberts, Lesley Voss, Emma J. Best, and Rachel Webb
Table
Comparison of characteristics of cases of pediatric GAS primary peritonitis at Starship Children’s Hospital, New Zealand, 2010–2022, to previously described cases*
| Pediatric GAS primary peritonitis | Cases from literature review, 1980–2022, n = 26 [3,4,14–30] | Cases from Starship Hospital, Jan 1, 2010–Jun 30, 2022, n = 20 |
|---|---|---|
| Median age (range) |
7 y (2 wk–16 y) |
2 y (3 wk–13 y) |
| Sex | ||
| F | 16/19 (84) | 11/20 (55) |
| M |
3/19 (16) |
9/20 (45) |
| Preceding throat or skin infection | ||
| Pharyngitis | 4/18 (22) | 1/20 (5) |
| Skin |
3/18 (17) |
5/20 (25) |
| STSS |
7/18 (39) |
6/20 (30) |
| Microbiology | ||
| Peritoneal fluid or tissue | 25/26 (96) | 17/20 (85) |
| Blood culture | 5/26 (19) | 9/20 (45) |
| Other | 1/26† | 4/20 (20)‡ |
| Molecular method (16S) | 3/25 (12) | 0/20 |
| Culture |
22/25 (88) |
19/20 (95) |
| Surgery | , | |
| Laparoscopy or laparotomy | 21/25 (84%)§ | 19/20 (95) |
| VATS only |
NA |
1/20 (5) |
| Median antibiotic duration (range), d |
14 (10–61) |
21 (14–42) |
| Clindamycin treatment | 4/14 (29) | 4/20 (20) |
| IVIG treatment |
3/14 (21) |
1/20 (5) |
| Median length of hospital stay (range), d |
10 (4–47) |
13 (5–31) |
| Deaths |
0/19 |
0/20 |
| emm types | 3.1 (n = 1) | 88 (n = 1), 65/69 (n = 1), 114 (n = 2), 118 (n = 1)§ |
| M-type | M3 (n = 1), M81 (n = 1), M2 (n = 1) | NA |
*Values are no. (%) except as indicated. IVIG, intravenous immunoglobulin; NA, not available; STSS, streptococcal toxic shock syndrome; VATS, video-assisted thoracoscopic surgery. †From pleural aspirate. ‡From skin swab samples; 3/4 GAS-positive skin swabs also had a positive blood or intraoperative peritoneal culture. §5/20 isolates were sent for emm typing.
Page created: August 31, 2023
Page updated: October 16, 2023
Page reviewed: October 16, 2023
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