Volume 28, Number 2—February 2022
CME ACTIVITY - Research
Epidemiology of Hospitalized Patients with Babesiosis, United States, 2010–2016
, Jonathan R. Day, Peter J. Krause, Anne Kjemtrup, Sheila F. O’Brien, Aaron A.R. Tobian, and Ruchika Goel
Table 2
Disease severity, risk for death, and concurrent conditions in hospitalizations in which babesiosis was listed as an admitting diagnoses, United States, 2010–2016*
| Disease severity and conditions | All data, no. (%) | ICD 9 data, 2010–2015q3,† no. (%) | ICD10 data, 2015q4–2016,† no. (%) |
|---|---|---|---|
| APD-RG severity of illness | |||
| Minor | 376 (4.8) | 316 (5.0) | 60 (4.1) |
| Moderate | 2,863 (36.6) | 2,318 (36.4) | 545 (37.6) |
| Major | 3,660 (46.8) | 2,990 (47.0) | 670 (46.2) |
| Extreme |
914 (11.7) |
744 (11.7) |
170 (11.7) |
| APD-RG risk for death | |||
| Minor | 2,004 (25.6) | 1,639 (25.7) | 365 (25.2) |
| Moderate | 2,852 (36.5) | 2,377 (37.3) | 475 (32.8) |
| Major | 2,178 (27.9) | 1,718 (27.0) | 460 (31.7) |
| Extreme |
779 (10.0) |
634 (10.0) |
145 (10.0) |
| Concurrent conditions | |||
| Decreased splenic function or asplenia | 560 (7.2) | 475 (7.1) | 85 (5.9) |
| HIV‡ | 20 (0.3) | 15 (0.2) | ‡ |
| Sickle cell disease | 30 (0.4) | 30 (0.5) | ‡ |
| Lyme disease (any diagnosis) | 1,953 (25.0) | 1,573 (24.7) | 380 (26.2) |
| Lyme disease (primary diagnosis) | 276 (3.5) | 221 (3.5) | 55 (3.8) |
| Anaplasmosis and ehrlichiosis | 658 (8.4) | 548 (8.6) | 110 (7.6) |
| Malaria | 52 (0.7) | 32 (0.5) | 20 (1.4) |
| Rocky Mountain spotted fever/rickettsial illness | 25 (0.1) | 20 (0.3) | § |
| Powassan virus disease, other tick-borne viral encephalitis | § | § | § |
| Relapsing fever | § | § | § |
*Data are from the NIS, which offers a representative sampling of US-based hospitals. APR-DRG, All Patient Refined Diagnosis Related Group; HCUP, Healthcare Cost and Utilization Project; ICD-9, International Classification of Diseases, Ninth Revision; ICD-10, International Classification of Diseases, Tenth Revision; NIS, National Inpatient Sample. †Because of the transition from ICD-9-CM to ICD-10-CM in October 2015, the data represent 2 time periods. ICD-9 data reflect 2010 through the third quarter of 2015 (2015q3), and ICD-10 data represent the fourth quarter of 2015 (2015q4) through 2016. ‡Data from 2011–2014 not available. §Statistics that are based on estimates with a relative SE (SE/weighted estimate) >0.30 or a total cell count <10 in the NIS are not reliable. These statistics are suppressed per HCUP policies.