Resources, Education & References for HPV Vaccination

Vaccine Recommendations

• Human Papillomavirus (HPV) ACIP Vaccine Recommendations

HPV Vaccine

• Markowitz LE, Gee J, Chesson H, Stokley S. Ten years of human papillomavirus vaccination in the United States. Acad Pediatr. 2018;18:S3-10.
• Markowitz LE, Schiller JT. Human Papillomavirus Vaccines. J Infect Dis. 2021;224(Supplement_4):S367-S378.
• Laprise JF, Chesson HW, Markowitz LE, et al. Effectiveness and Cost-Effectiveness of Human Papillomavirus Vaccination Through Age 45 Years in the United States. Ann Intern Med. 2020;172(1):22-29.

HPV Vaccine Safety

• For the most up-to-date information on HPV vaccine safety, visit HPV Vaccine Safety and Effectiveness Data.

HPV Vaccine Impact

• Rosenblum HG, Lewis RM, Gargano JW, et al. Declines in Prevalence of Human Papillomavirus Vaccine-Type Infection Among Females after Introduction of Vaccine – United States, 2003-2018. MMWR. 2021;70:415-20.

• Meites E, Stone L, Amiling R, et al. Significant Declines in Juvenile Onset Recurrent Respiratory Papillomatosis following HPV Vaccine Introduction in the United States. Clin Infect Dis. 2021;3(5):885-890.

• McClung NM, Gargano JW, Park IU, et al; HPV-IMPACT Working Group. Estimated number of cases of high-grade cervical lesions diagnosed among women – United States, 2008 and 2016. MMWR. 2019;68(15):337-343.
• McClung NM, Lewis RM, Gargano JW, et al. Declines in Vaccine-Type Human Papillomavirus Prevalence in Females Across Racial/Ethnic Groups: Data From a National Survey. J Adolesc Health. 2019;65:715-722.
• McClung NM, Gargano JW, Bennett NM, et al, HPV-IMPACT Working Group. Trends in Human Papillomavirus Types 16 and 18 in Cervical Precancers, 2008-2014. Cancer Epidemiol Biomarkers Prev. 2019;28(3):602-609.
• Gargano J, Park IU, Griffin MR et al. Trends in High-grade Cervical Lesions and Cervical Cancer Screening in Five States, 2008–2015. Clin Infect Dis. 2019;68(8):1282-91.
• Drolet M, Benard E, Perez N, Brisson M, on behalf of the HPV Vaccination Impact Study Group. Population-level impact and herd effects following human papillomavirus vaccination programs: updated systematic review and meta-analysis. The Lancet. 2019;394:497-509.
• Flagg EW, Torrone EA. Declines in Anogenital Warts Among Age Groups Most Likely to Be Impacted by Human Papillomavirus Vaccination, United States, 2006-2014. Am J Public Health. 2018;108(1):112-119.
• Oliver SE, Unger ER, Lewis R, et al. Prevalence of Human Papillomavirus Among Females After Vaccine Introduction-National Health and Nutrition Examination Survey, United States, 2003-2014. J Infect Dis. 2017;216:594-603.
• Benard VB, Castle PE, Jenison SA, et al. Population-based incidence rates of cervical intraepithelial neoplasia in the human papillomavirus vaccine era. JAMA Oncol. 2017;3(6):833-837.
• Flagg EW, Torrone EA, Weinstock H. Ecological association of human papillomavirus vaccination with cervical dysplasia prevalence in the United States, 2007–2014. Am J Public Health. 2016;106(12):2211–2218.

HPV Vaccine and Sexual Behavior

• Madhivanan P, Pierre-Victor D, Mukherjee S, et al. Human papillomavirus vaccination and sexual Disinhibition in females: a systematic review. Am J Prev Med. 2016;51(3):373–83.
• Hansen BT, Kjaer SK, Arnheim-Dahlstrom L, et al. Human papillomavirus (HPV) vaccination and subsequent sexual behaviour: evidence from a large survey of Nordic women. Vaccine. 2014;32:4945-53.
• Bednarczyk RA, Davis R, Ault K, et al. Sexual activity-related outcomes after human papillomavirus vaccination of 11- to 12-year-olds. Pediatrics. 2012;130(5):798-805.
• Forster AS, Marlow LA, Stephenson J, et al. Human papillomavirus vaccination and sexual behaviour: cross-sectional and longitudinal surveys conducted in England. Vaccine. 2012;30(33):4939-44.

HPV Vaccination Coverage Issues

• Pingali C, Yankey D, Elam-Evans LD, et al. National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13-17 Years – United States, 2020. MMWR. 2021;70(35):1183-1190.

• Special issue: Raising HPV Vaccination Coverage Rates in Academic Pediatrics,
• Brewer NT, Hall ME, Malo TL, et al.  Announcements versus conversations to improve HPV vaccination coverage: a randomized trial. Pediatrics. 2017;139(1):e20161764.
• Smulian EA, Mitchell KR, Stokley S. Interventions to increase HPV vaccination coverage: A systematic review. Hum Vaccin Immunother. 2016;12:1566-88.
• Perkins RB, Clark JA, Apte G, et al. Missed Opportunities for HPV Vaccination in Adolescent Girls: A Qualitative Study. Pediatrics. 2014;134(3):e666-74.

Materials for Healthcare Professionals

• Pink Book Chapter on Human Papillomavirus
• Ask the Experts: HPV
• Traveler’s Health (Yellow Book) Chapter on Sexually Transmitted Diseases
• HPV Vaccination Coverage Data
• Addressing Parents’ Top Questions About HPV Vaccine [1 page]
• Top 10 Ways to Improve HPV Vaccination Rates in Your Practice [1 page]
• Speaking About HPV Vaccine to Your Colleagues
• HPV Vaccine Tools and Materials for Your Office
• Child and Adolescent Immunization Schedule

Provider Education

• You Are The Key to HPV Cancer Prevention (CME/CE credit is available.)
• You Call the Shots: Web-Based Training Course (CME/CE credit is available.)

Resources for Patients

• HPV (Human Papillomavirus) Gardasil-9 Vaccine Information Statement (VIS)
  In English | Other languages
• HPV Vaccine Information for Parents
• Flyers/Posters for Preteens and Teens
• HPV Vaccine Safety
• HPV Vaccine | Human Papillomavirus (HPV) | CDCHPV Vaccine Information for Young Women
• What Parents Should Know About HPV Vaccine Safety and Effectiveness [1 page]
• HPV and Cancer
• Basic Information About Cervical Cancer
• Vaccines for Teens 11-12 Years | CDC
• HPV and Oropharyngeal Cancer

Other Resources

• HPV-associated Cancer Statistics
• 9vHPV (Gardasil-9) Package Insert [23 pages]
• TeenVax View