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Table 29. Early Non-Primary Non-Secondary Syphilis — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States and Territories, 2018–2022

Table 29. Early Non-Primary Non-Secondary Syphilis — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States and Territories, 2018–2022
State/Territory Cases Rates per 100,000 Population
2018 2019 2020 2021 2022 2018 2019 2020 2021 2022
Alabama 447 540 479 676 881 9.1 11.0 9.5 13.4 17.4
Alaska 41 78 130 132 116 5.6 10.7 17.7 18.0 15.8
Arizona 898 1,179 1,249 1,476 1,581 12.5 16.2 17.5 20.3 21.5
Arkansas 364 267 234 527 454 12.1 8.8 7.8 17.4 14.9
California 7,708 8,284 7,673 8,504 8,859 19.5 21.0 19.4 21.7 22.7
Colorado 362 453 519 519 606 6.4 7.9 9.0 8.9 10.4
Connecticut 77 159 207 284 275 2.2 4.5 5.7 7.9 7.6
Delaware 36 65 70 89 55 3.7 6.7 7.1 8.9 5.4
District of Columbia 336 414 369 233 494 47.8 58.7 53.5 34.8 73.5
Florida 3,939 4,142 4,423 5,731 6,035 18.5 19.3 20.5 26.3 27.1
Georgia 1,517 1,733 1,719 1,804 1,814 14.4 16.3 16.0 16.7 16.6
Hawaii 87 95 90 105 106 6.1 6.7 6.2 7.3 7.4
Idaho 33 40 36 61 65 1.9 2.2 2.0 3.2 3.4
Illinois 1,464 1,345 1,227 1,167 1,265 11.5 10.6 9.6 9.2 10.1
Indiana 359 326 471 624 612 5.4 4.8 6.9 9.2 9.0
Iowa 85 100 163 216 293 2.7 3.2 5.1 6.8 9.2
Kansas 291 282 234 239 271 10.0 9.7 8.0 8.1 9.2
Kentucky 294 395 352 576 667 6.6 8.8 7.8 12.8 14.8
Louisiana 576 576 614 798 884 12.4 12.4 13.2 17.3 19.3
Maine 43 53 28 40 30 3.2 3.9 2.1 2.9 2.2
Maryland 857 991 891 NR 734 14.2 16.4 14.4 11.9
Massachusetts 620 625 548 626 780 9.0 9.1 7.8 9.0 11.2
Michigan 407 558 566 732 749 4.1 5.6 5.6 7.3 7.5
Minnesota 286 367 368 415 535 5.1 6.5 6.4 7.3 9.4
Mississippi 937 1,222 1,275 592 429 31.4 41.1 43.1 20.1 14.6
Missouri 546 647 556 787 781 8.9 10.5 9.0 12.8 12.6
Montana 25 25 21 22 84 2.4 2.3 1.9 2.0 7.5
Nebraska 37 46 50 78 98 1.9 2.4 2.5 4.0 5.0
Nevada 512 522 496 723 829 16.9 16.9 16.0 23.0 26.1
New Hampshire 41 49 32 39 33 3.0 3.6 2.3 2.8 2.4
New Jersey 788 827 790 1,134 1,167 8.8 9.3 8.5 12.2 12.6
New Mexico 161 203 243 215 267 7.7 9.7 11.5 10.2 12.6
New York 4,097 4,376 4,770 5,524 5,672 21.0 22.5 23.6 27.8 28.8
North Carolina 797 989 1,105 1,331 1,711 7.7 9.4 10.6 12.6 16.0
North Dakota 13 10 12 22 22 1.7 1.3 1.5 2.8 2.8
Ohio 481 519 555 874 1,083 4.1 4.4 4.7 7.4 9.2
Oklahoma 342 339 380 568 608 8.7 8.6 9.6 14.2 15.1
Oregon 299 357 304 478 523 7.1 8.5 7.2 11.3 12.3
Pennsylvania 1,192 1,138 1,166 1,478 1,661 9.3 8.9 9.0 11.4 12.8
Rhode Island 71 109 97 119 107 6.7 10.3 8.8 10.9 9.8
South Carolina 732 681 796 972 995 14.4 13.2 15.6 18.7 18.8
South Dakota 9 8 38 353 730 1.0 0.9 4.3 39.4 80.2
Tennessee 472 639 686 839 888 7.0 9.4 9.9 12.0 12.6
Texas 4,245 4,065 5,411 7,283 8,534 14.8 14.0 18.6 24.7 28.4
Utah 101 120 81 131 181 3.2 3.7 2.5 3.9 5.4
Vermont 18 11 11 4 2 2.9 1.8 1.7 0.6 0.3
Virginia 668 679 646 642 790 7.8 8.0 7.5 7.4 9.1
Washington 599 721 617 866 1,044 7.9 9.5 8.0 11.2 13.4
West Virginia 55 83 111 99 103 3.0 4.6 6.2 5.6 5.8
Wisconsin 163 193 230 375 401 2.8 3.3 3.9 6.4 6.8
Wyoming 11 10 6 10 9 1.9 1.7 1.0 1.7 1.5
US TOTAL 38,539 41,655 43,145 51,830 56,913 11.8 12.7 13.0 15.6 17.1
    Northeast 6,947 7,347 7,649 9,248 9,727 12.4 13.1 13.3 16.2 17.1
    Midwest 4,141 4,401 4,470 5,882 6,840 6.1 6.4 6.5 8.5 9.9
    South 16,614 17,820 19,561 23,458 26,076 13.3 14.2 15.5 18.4 20.3
    West 10,837 12,087 11,465 13,242 14,270 13.9 15.4 14.6 16.8 18.1
American Samoa 0 0 0 0 0 0.0 0.0 0.0 0.0 0.0
Commonwealth of the Northern Mariana Islands 0 0 0 0 3 0.0 0.0 0.0 0.0 5.8
Guam 3 5 0 5 2 1.8 3.0 0.0 3.0 1.2
Puerto Rico 577 458 332 400 524 17.5 14.3 10.1 12.3 16.3
US Virgin Islands NR NR 9 12 8 8.5 11.3 7.6
TERRITORIES TOTAL 580 463 341 417 537 16.3 13.4 9.3 11.5 14.9
TOTAL 39,119 42,118 43,486 52,247 57,450 11.8 12.7 13.0 15.6 17.1
NR = No report.
NOTE: See Technical Notes for more information on syphilis case reporting and on interpreting case counts and rates in US territories. This report includes data from years that coincide with the COVID-19 pandemic, which introduced uncertainty and difficulty in interpreting case data. See Impact of COVID-19 on STIs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STI case notification data. Although 2021 data from Maryland are included in national and regional case counts and rates displayed in this table, state-specific data have been suppressed.
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