Smallpox Specimen Packaging and Shipping

What to know

  • High-risk specimens must be packaged, labeled, and shipped as Category A infectious substances affecting humans (UN 2814).
  • Low- and moderate-risk specimens must be packaged, labeled, and shipped as Category B infectious substances affecting humans (UN 3373).
  • Specimens require CDC Form 50.34 and the Poxvirus Human Specimen Submission Form.

Forms to include

Complete and submit CDC Form 50.34 and the Poxvirus Human Specimen Submission Form (provided at time of consultation) with the shipment.

Specimen packaging

Category A infectious substance

Package, label, and ship high-risk specimens as a Category A infectious substance affecting humans (UN 2814) in accordance with the U.S. Department of Transportation's Hazardous Materials Regulations and the International Air Transport Association Dangerous Goods Regulations.

Diagram showing how to securely package Category A infectious substances for shipping
High-risk specimens are shipped as Category A infectious substances.

All persons packing and shipping infectious materials must be trained and certified every two years in compliance with the Department of Transportation or the International Air Transport Association.

  • Triple pack all specimens in:
    • Leakproof primary receptacle; multiple primary receptacles should be individually wrapped or separated
    • Leakproof secondary receptacle, and
    • Rigid outer packaging
  • If specimen is a liquid, place absorbent material between the primary and secondary receptacle.
  • Place a list of contents and paperwork between the secondary receptacle and outer packaging.
  • Label outer packaging with:
    • Infectious substance (diamond shaped label)
    • Proper shipping name and UN 2814 certification mark
    • Shipper and consignee identification (name, address, and telephone)
    • Package orientation arrows if primary receptacle exceeds 50 mL or more

Category B infectious substance

Package, label, and ship low- or moderate-risk specimens as a Category B infectious substance (UN 3373) in accordance with the U.S. Department of Transportation's Hazardous Materials Regulations and the International Air Transport Association Dangerous Goods Regulations.

Diagram showing how to securely package Category B infectious substances for shipping
Low- or moderate-risk specimens are shipped as Category B infectious substances.
  • Triple pack the specimens in:
    • Leakproof primary receptacle; multiple primary receptacles should be individually wrapped or separated
    • Leakproof secondary receptacle
    • Rigid or strong outer packaging
  • If specimen is a liquid, place absorbent material between the primary and secondary receptacle.
  • Place a list of contents and paperwork between the secondary receptacle and outer packaging.
  • Label outer package with:
    • Proper shipping name and UN 3373 certification mark
    • Shipper and consignee identification (name, address, and telephone)
    • Package orientation arrows if primary receptacle exceeds 50 mL or more

Specimen shipping

Ship to the following address

Centers for Disease Control and Prevention

Attn: STAT Lab / Poxvirus Program

1600 Clifton Road NE

Atlanta, GA 30329

Phone: 404.639.4129