Vaccine Adverse Reaction Images
This information is about preventing or responding to smallpox. For the latest information about the current mpox outbreak, including information on symptoms, prevention, and vaccines, please visit CDC’s Mpox site.
The images below show examples of autoinoculation sites and adverse reactions to the smallpox vaccine. Find images of normal reactions on the “major takes” page.
Pictures labeled from CDC are in the public domain. All other pictures are posted with the permission of the copyright holders and may be downloaded for personal use but may not be reproduced without the express permission of the copyright holder.
![who_vn.jpg Fatal progressive vaccinia in a child with an immunodeficiency.](/smallpox/images/vaccine-reactions/who_vn.jpg?_=03127)
![bt2.jpg Child with auto-inoculation of cheek and arm with vaccinia virus.](/smallpox/images/vaccine-reactions/bt2-200.jpg?_=03128)
![who_ai.jpg Woman with accidental auto-inoculation of lower eyelid with vaccinia virus.](/smallpox/images/vaccine-reactions/who_ai.jpg?_=03123)
![bt5.jpg Accidental auto-inoculation of eyelid with vaccinia virus with concurrent cellulitis.](/smallpox/images/vaccine-reactions/bt5-200.jpg?_=03126)
![bt4.jpg Generalized vaccinia in child.](/smallpox/images/vaccine-reactions/bt4-200.jpg?_=03129)
![bt9.jpg Eczema vaccinatum on the face of a child.](/smallpox/images/vaccine-reactions/bt9-200.jpg?_=03126)
![bt10.jpg Eczema vaccinatum on the arms, torso, and legs of a child.](/smallpox/images/vaccine-reactions/bt10-500.jpg?_=03124)
![bt14.jpg Eczema vaccinatum in contact to recently vaccinated child.](/smallpox/images/vaccine-reactions/bt14.jpg?_=03131)
![who_ev.jpg Eczema vaccinatum in an unvaccinated contact to a vaccinated sibling.](/smallpox/images/vaccine-reactions/who_ev.jpg?_=03133)
![bt11.jpg Progressive vaccinia in patient with chronic granulocytic leukemia.](/smallpox/images/vaccine-reactions/bt11-500.jpg?_=03130)
![bt15.jpg Another view of progressive vaccinia lesion in patient with chronic granulocytic leukemia.](/smallpox/images/vaccine-reactions/bt15-500.jpg?_=03130)