At a glance
Poliovirus grows in nearly all human and monkey cell lines, in addition to mouse L cells (L20B, Lα) that express the human poliovirus receptor (CD155). The lists below highlights some, but not all, cell lines susceptible to poliovirus.
Poliovirus Sensitive Cell Lines
Cell Line
Origin
A-549
Human
CaCo-2
Human
HEK
Human
HeLA
Human
HEp-2
Human
MRC-5
Human
PERC-6
Human
RD
Human
WI-38
Human
Various neuroblastoma (e.g. IMR-32, SK-N-MC)
Human
BGMK (sometimes referred to as BGM or GMK)
African green monkey
LLC-MK2
Rhesus macaque
MA-104 (Vero derivative)
African green monkey
Primary monkey kidney cells
Old world monkeys
Vero
African green monkey
L20B
Transgenic mouse cell line
la
Transgenic mouse cell line
E-MX
Hybrid; mixture of cell lines
R-MX
Hybrid; mixture of cell lines
Content Source:
Office of Readiness and Response